A5017666348- Systemic Lupus Erythematosus Research
- Pregnancy and Medication Impact
- Pregnancy and preeclampsia studies
- Reproductive System and Pregnancy
- Cardiovascular Issues in Pregnancy
- Blood Coagulation and Thrombosis Mechanisms
- Iron Metabolism and Disorders
- Parvovirus B19 Infection Studies
- Eosinophilic Esophagitis
- Atherosclerosis and Cardiovascular Diseases
- Venous Thromboembolism Diagnosis and Management
- Hemoglobinopathies and Related Disorders
- Renal Diseases and Glomerulopathies
- Gestational Diabetes Research and Management
- Maternal and Neonatal Healthcare
- Herpesvirus Infections and Treatments
- Software Engineering Techniques and Practices
- Vasculitis and related conditions
- Muscle and Compartmental Disorders
- Maternal and fetal healthcare
- Dialysis and Renal Disease Management
- Electrolyte and hormonal disorders
- Cancer Risks and Factors
- Platelet Disorders and Treatments
- Nutritional Studies and Diet
Universidade do Estado do Rio de Janeiro
2015-2025
Hospital Universitário Pedro Ernesto
2018-2023
Universidade Federal do Rio de Janeiro
2008-2022
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2008
Hospital Universitário Antônio Pedro
2006
Objective This study analyzed longitudinal trajectories of soluble fms‐like tyrosine kinase‐1 (sFlt‐1) and placental growth factor (PlGF) sFlt‐1/PlGF ratio in a cohort pregnant patients with systemic lupus erythematosus (SLE). Methods Blood samples were collected (14‐18, 24‐26, 30‐32, 34‐36 38‐40 weeks), stored at ‐80°C evaluated for serum levels sFlt‐1, PlGF sFlt1/PlGF ratios. Patients classified as inactive SLE (SLEPDAI < 4), active disease > or preeclampsia (PE). Medians...
To analyze the impact of different classes lupus nephritis as risk variables for maternal and fetal adverse outcomes in a cohort pregnant patients.This is study with retrospective prospective data collection, conducted at University Hospital State Rio de Janeiro, Brazil, from 2011 to 2016. A total 147 pregnancies 137 systemic erythematosus patients whom 66 had were included. Demographic clinical features, well observed each histological class among compared those without nephritis....
<i>Background:</i> Oxidative modification of low-density lipoprotein (LDL) has been demonstrated in patients with end-stage renal disease, where it is associated oxidative stress and plays a key role the pathogenesis atherosclerosis. In this context, generation minimally oxidized LDL, also called electronegative LDL [LDL(–)], active detectable sign atherogenic tendencies. The purpose study was to evaluate serum LDL(–) levels anti-LDL(–) IgG autoantibodies disease on dialysis,...
Objective To evaluate mean serum levels of vascular endothelial growth factor (VEGF), placental (PlGF), and soluble Flt‐1 (sFlt‐1) in pregnant patients with systemic lupus erythematosus (SLE) inactive disease, active nephritis, preeclampsia for differential diagnosis between these conditions. Methods Pregnant women SLE, singleton pregnancies no other autoimmune diseases, were classified according to disease activity (inactive SLE nephritis) the presence preeclampsia. Serum samples collected...
A anemia carencial é um problema nutricional comum, e sua prevalência alta entre mulheres em idade reprodutiva. O ginecologista-obstetra que atua como médico de atenção primária pode desempenhar papel fundamental na detecção tratamento por deficiência ferro. Além disso, o a profilaxia da durante período gestacional funcionam forma prevenir distúrbios podem repercutir infância, parto prematuro, baixo peso ao nascimento dificuldades cognitivas do recém-nascido. gravidez aproximadamente 40%,...
This study analyzed maternal and fetal outcomes of pregnancies neuropsychiatric systemic lupus erythematosus patients followed in a reference unit. retrospective cohort included 26 seen between 2011 2015 with history and/or active among 135 pregnancies. Three had at conception, but only one remained neurological activity during gestation, characteristically related to the inadvertent suspension medications. Twenty six percent newborns were small for gestational age 40% live births premature,...
This study was designed to determine the seroprevalence of herpes simplex virus type 2 (HSV-2) and evaluate its association with age, sex as well other demographic behavioural factors in 150 human immunodeficiency (HIV) positive adults patients attending general medical outpatient ward for routine care Niterói, state Rio de Janeiro, Brazil. Serum samples were screened HSV-2 antibodies using an indirect ELISA. Eighty-three men (mean age: 38.8) 67 women 35.4). The estimated prevalence 52% (95%...
This article describes three complicated cases in rheumatology and pregnancy. The first case elucidates the challenges treating SLE conjunction with pulmonary arterial hypertension, while second features an SLE-affected pregnancy development of portal hypertension secondary to vein thrombosis related APS. third is a pregnant woman stable who developed thrombotic microangiopathy caused by atypical haemolytic uraemic syndrome, failed improve despite multiple measures including biopsy elective...
SUMMARY OBJECTIVE: The aim of this study was to analyze the occurrence and risk factors associated with infections during pregnancy in patients systemic lupus erythematosus. METHODS: This is a retrospective cohort using data pregnant women who were followed up between 2011 2018 at university hospital. RESULTS: 221 erythematosus analyzed. incidence 22.6% (50/221), urinary tract being most frequent site infection (32/221, 14.5%) by respiratory (15/221, 6.8%). bivariate analysis showed that...
The objective of this study was to evaluate the potential impact irreversible damage accrual in women with systemic lupus erythematosus (SLE) and adverse maternal and/or fetal/neonatal outcomes.Retrospective cohort SLE pregnant patients carried out from January 2011 2020 at Hospital University Pedro Ernesto (HUPE) State Rio de Janeiro, Brazil. Irreversible defined according SLICC/ACR index (SDI). association SDI on pregnancy outcomes established by univariate multivariate regression models...
Pre-eclampsia is a leading cause of maternal morbidity and mortality, perinatal death, premature birth intrauterine growth restriction. Although most women present good outcome, the delay in diagnosis may contribute to evolution more severe form, eclampsia. A large number studies have been published on this subject, yet etiology pre-eclampsia remains unknown. The study angiogenic factors, such as vascular endothelial factor (VEGF) placental (PlGF), antiangiogenic soluble fms-like tyrosine...
As mudanças anatômicas e hormonais que ocorrem no organismo da mulher tornam as gestantes suscetíveis, expostas aos riscos de novo evento trombótico durante a gravidez. Dessa forma, é importante sabermos atuar na profilaxia termos conhecimento do uso anticoagulação em situações especiais patologias onde trombose pode ocorrer ausência um manejo adequado. Nessas ocasiões escolha anticoagulante se transforma grande desafio. Os cumarínicos são drogas atuam inibição síntese dos fatores...
A morbidade gestacional é uma forma bem reconhecida de apresentação da síndrome antifosfolipídeo (SAF), que parte do critério classificação. SAF obstétrica responsável por causar grandes impactos emocionais devido às perdas gestacionais ocasiona e financeiros em virtude aumento gestacional. Depois diagnóstico apropriado, o tratamento pacientes com gera um significativo na taxa nascidos vivos, embora risco outras morbidades obstétricas como pré-eclâmpsia, restrição crescimento fetal (CIUR)...
Introdução: A amamentação é uma prática de suma importância para a saúde materna e neonatal. O aleitamento materno exclusivo recomendado por, pelo menos, 4 meses está associado, acordo com Organização Mundial Saúde (OMS), redução 13% na mortalidade infantil até os 5 anos. Apesar dos benefícios, muitas pacientes portadoras doenças crônicas, como o caso do lúpus eritematoso sistêmico (LES), são desencorajadas mal orientadas sobre realização materno. Objetivo: Descrever forma tempo LES...
Introdução: A anemia falciforme (AF) é uma doença hematológica que causa deformidade estrutural da hemoglobina. O curso na gestação imprevisível devido à alta variabilidade dos fenótipos clínicos AF. Embora a maioria das gestações em mulheres com diagnóstico de resulte nascimentos fetos saudáveis, essas apresentam risco aumentado complicações materno-fetais, além maior chance descompensação subjacente. Objetivo: Avaliar os desfechos gestacionais pacientes (DF), analisando as potenciais...