- Atherosclerosis and Cardiovascular Diseases
- Metabolomics and Mass Spectrometry Studies
- Systemic Lupus Erythematosus Research
- Monoclonal and Polyclonal Antibodies Research
- Pericarditis and Cardiac Tamponade
- Lipoproteins and Cardiovascular Health
- Leprosy Research and Treatment
- SARS-CoV-2 detection and testing
- Cardiac tumors and thrombi
- Adipokines, Inflammation, and Metabolic Diseases
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Myasthenia Gravis and Thymoma
- Vasculitis and related conditions
- Autoimmune Bullous Skin Diseases
- Mental Health Research Topics
- Hemoglobinopathies and Related Disorders
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Chronic Lymphocytic Leukemia Research
- Vascular anomalies and interventions
- Sepsis Diagnosis and Treatment
- Poisoning and overdose treatments
- Urologic and reproductive health conditions
- Methemoglobinemia and Tumor Lysis Syndrome
- Chemotherapy-related skin toxicity
Hospital Prof. Dr. Fernando Fonseca
2015-2024
Universitario Francisco de Asís
2024
Universidade Nova de Lisboa
2024
BackgroundLocalized stress and cell death in chronic inflammatory diseases may release tissue-specific lipids into the circulation causing blood plasma lipidome to reflect type of inflammation. However, deep lipid profiles major have not been compared.MethodsPlasma lipidomes patients suffering from two etiologically distinct diseases, atherosclerosis-related vascular disease, including cardiovascular (CVD) ischemic stroke (IS), systemic lupus erythematosus (SLE), were screened by a top-down...
A 40-year-old man presented to the emergency department with dyspnoea and fatigue after bupropion popper consumption. Clinical examination was remarkable for central cyanosis not responding supplementary oxygen. Arterial blood gas analysis showed a methaemoglobin value of 30.3%. Methaemoglobinemia diagnosed patient treated methylene blue. However, during blue administration, developed generalized tonic-clonic seizure that successfully managed diazepam. Combined intoxications can be critical...
Background Adults are being vaccinated against SARS-CoV-2 worldwide, but the longitudinal protection of these vaccines is uncertain, given ongoing appearance variants. Children remain largely unvaccinated and susceptible to infection, with studies reporting that they actively transmit virus even when asymptomatic, thus affecting community. Methods We investigated if saliva an effective sample for detecting RNA antibodies in children, associated viral levels infectivity. For that, we used a...
Introduction Treatment Resistant Depression is a challenging condition with poor outcome and limited therapeutic options. Esketamine the enantiomer of Ketamine has recently been approved marketed for treating depression. Questions remain about its short- long-term benefit, as well usefulness in suicide risk. Hopelessness one symptoms most closely associated Objectives The aim this paper to evaluate effect drug on hopelessness after month treatment Esketamine. Methods Beck Scale (BHS) was...
Objetivo: Relatar a experiência de acadêmicos enfermagem em uma qualificação para equipe Saúde da Família Ribeirinha sobre primeiros socorros básicos comunidade integrada ao município Belém do Pará. Relato experiência: Trata-se um relato experiência, descritivo, com abordagem qualitativa vivenciado no mês outubro 2023 por curso encontro profissional temática noções básicos, o qual foi fundamentado arco Charles Maguerez suas cinco etapas. A incluiu apresentação das manobras desengasgo, bem...
<h3>Background:</h3> Giant Cell Arteritis (GCA) is the most frequent vasculitis in patients older than 50 years-old. Increasing use of imaging tools for diagnosis GCA led to recognition extracranial Large-Vessel (LV-GCA) involvement a significant proportion patients. Around two-thirds with are reported have LV-GCA [1,2]. phenotypes may vary according age at diagnosis, cranial manifestations being more prominent and younger 65 years-old [3]. Atherosclerosis highly prevalent among an advanced...
Objetivo: Relatar a experiência de acadêmicos do curso enfermagem frente uma ação educativa acerca noções básicas primeiros socorros. Relato experiência: Desenvolvido por discentes 5° e 6° durante disciplina “Projeto Integrador IV”. Na análise da amostra constatou-se que 90% dos servidores não obtinham conhecimento geral sobre prática Nesse sentido, quando os questionaram noção imobilização, 100% trabalhadores sabiam se tratava, em contrapartida, 30% alunos também participaram social,...
<h3>Background</h3> Systemic Lupus Erythematosus (SLE) is considered an independent risk factor for cardiovascular disease and patients with SLE have increased burden of atherosclerotic vascular disease<sup>1</sup>. High-density lipoproteins (HDL) are the plasma responsible reverse cholesterol transport<sup>2</sup>. HDL protective effect on attributed to efflux capacity as well its anti-oxidant anti-inflammatory properties<sup>3</sup>. Dyslipidemia frequent amongst SLE, characteristically...
(1) Background: Treatment of patients with rheumatoid arthritis (RA) an anti-IL-6 receptor (anti-IL-6R) monoclonal antibody (tocilizumab) has been found to influence iron metabolism. The objective the present study was ascertain whether changes in metabolism induced by anti-IL-6R biologic therapy were independently associated increased infection risk. (2) Methods: A prospective longitudinal RA treated tocilizumab conducted. antitumor necrosis factor α also included as a control group....
Introdução: A pericardite aguda é uma síndrome frequente caracterizada pela inflamação do pericárdio e usualmente atribuído a etiologia viral/idiopática. Apesar dos avanços no tratamento, existe informação limitada em relação prognóstico. O objetivo nosso trabalho foi identificar prevalência de com especifica avaliar marcadores clínicos prognóstico.
 Material Métodos: Estudo retrospetivo doentes hospitalizados por entre 2012-2016. população quanto etiologia, apresentação clínica,...
Aims: Inflammation impacts several acute and chronic diseases causing localized stress cell death, releasing tissue-specific lipids into the circulation from inflamed cells tissues. The plasma lipidome may be expected to reflect type of inflammation. However, deep lipid profiles major inflammatory have not been compared.Methods Results: We compared lipidomes patients suffering two etiologically distinct diseases, atherosclerosis-related cardiovascular disease (CVD) including ischemic stroke...
Structured abstract IMPORTANCE Adults are being vaccinated against SARS-CoV-2 worldwide, but the longitudinal protection of these vaccines is uncertain, given ongoing appearance variants. Children susceptible to infection, and some studies reported that they actively transmit virus even when asymptomatic, thus affecting community. Methods easily test infected children track carry in demand. OBJECTIVE To determine if saliva an effective sample for detecting RNA antibodies aged 10 years under,...
Mixed connective tissue disease (MCTD) is a rare autoimmune disorder that characterized by overlapping clinical features of systemic lupus erythematosus (SLE), scleroderma, and myositis. Both SLE mixed patients are more prone to have acute endocarditis, immunosuppression risk factor for recurrence infective endocarditis. We present the case 53-year-old female with presenting interstitial lung precapillary pulmonary hypertension. The patient was chronically medicated prednisolone,...
Sanchez, A. Y.; Suria, S.; Riaño, M.; Esparza, N.; Garcia-Canton, C.; Batista, F.; Auyanet, I.; Garcia-Nieto, V.; Checa, M. D. Author Information
<h3>Background and aims</h3> Systemic Lupus Erythematosus (SLE) is considered an independent risk factor for cardiovascular disease. ATP-binding cassette transporter ABCA1, also known as the cholesterol efflux regulator protein, a ubiquitous that highly expressed in macrophages. Its main function to donate apolipoproteinA-I lipid-poor HDL particles. As such, ABCA1 closely influences levels its role atherosclerosis has been increasingly studied. This study was undertaken determine if...