A5084308807- EEG and Brain-Computer Interfaces
- Intensive Care Unit Cognitive Disorders
- Respiratory Support and Mechanisms
- Cardiac Arrest and Resuscitation
- Palliative Care and End-of-Life Issues
- Anesthesia and Pain Management
- Neonatal and fetal brain pathology
- Attention Deficit Hyperactivity Disorder
- Family and Patient Care in Intensive Care Units
- Airway Management and Intubation Techniques
- Spine and Intervertebral Disc Pathology
- Anesthesia and Sedative Agents
- Neuroscience and Neural Engineering
- Pregnancy and preeclampsia studies
- Ultrasound in Clinical Applications
- Intraoperative Neuromonitoring and Anesthetic Effects
- Pleural and Pulmonary Diseases
- Maternal and Perinatal Health Interventions
- Pneumothorax, Barotrauma, Emphysema
- Axon Guidance and Neuronal Signaling
- COVID-19 and healthcare impacts
- Anesthesia and Neurotoxicity Research
- Angiogenesis and VEGF in Cancer
- Cardiac, Anesthesia and Surgical Outcomes
- Central Venous Catheters and Hemodialysis
Massachusetts General Hospital
2010-2025
Harvard University
2013-2021
Harvard–MIT Division of Health Sciences and Technology
2018
Massachusetts Institute of Technology
2018
Brigham and Women's Hospital
2017
Preliminary reports suggest that critically ill patients with coronavirus disease 2019 (COVID-19) infection requiring mechanical ventilation may have markedly increased sedation needs compared ill, mechanically ventilated without COVID-19. We conducted a study to examine sedative use for this patient population within multiple intensive care units (ICUs) of large academic medical center. A retrospective, single-center cohort practices COVID-19 during the first 10 days was in 8 ICUs at...
Do-not-resuscitate (DNR) orders instruct medical personnel to forego cardiopulmonary resuscitation in the event of arrest, but they do not preclude surgical management. Several studies have reported that DNR status is an independent predictor 30-day mortality; however, etiology increased mortality remains unclear. We hypothesized patients would demonstrate postoperative mortality, morbidity, relative non-DNR undergoing same procedures.Using American College Surgeons National Surgical Quality...
Patients with autism spectrum disorder (ASD) often require sedation or general anesthesia. ASD is thought to arise from deficits in GABAergic signaling leading abnormal neurodevelopment. We sought investigate differences how patients respond the drug propofol by comparing propofol-induced electroencephalogram (EEG) of and neurotypical (NT) patients. This investigation was a prospective observational study. Continuous 4-channel frontal EEG recorded during routine anesthetic care undergoing...
ABSTRACT Introduction: The COVID-19 pandemic has brought unprecedented numbers of patients with acute respiratory distress to medical centers. Hospital systems require rapid adaptation respond the increased demand for airway management while ensuring high quality patient care and provider safety. There is limited literature detailing successful system-level approaches adapt surge requiring management. Methods: A deliberate approach was used expand a preexisting response service. Through...
We report the case of a 34-year-old man who developed cardiac arrest due to tension hydrothorax from colonic perforation. Tension hydrothorax, an entity characterized by pleural effusion leading mediastinal compression, has not been reported in association with intraabdominal inflammation. Our patient respiratory insufficiency after repair perforation, followed failure and arrest. Transthoracic echocardiography provided rapid diagnosis during decompensation prompted lifesaving thoracostomy....
Abstract Introduction: Medulloblastoma contains a rich and abnormal vascular network offering potential target for anti-angiogenic treatment. However, in pediatric patients anti-VEGF treatments may have serious adverse effects other antiangiogenic drugs not shown efficacy. Placental growth factor (PlGF) is mediator of post-natal pathological angiogenesis, its inhibition be associated with significant side effects. Here, we examine the role PlGF medulloblastoma as therapy this brain tumor....
Balakrishna, Aditi; Walsh, Elisa; Hamidi, Arzo; Berg, Sheri; Austin, Daniel; Pino, Richard; Hanidziar, Dusan; Chang, Marvin; Bittner, Edward Author Information
( Reg Anesth Pain Med . 2021;46:258–267) Approximately 40% of women childbearing age are affected by vertebral column, spinal cord, and neuromuscular system disorders conditions, raising questions about neuraxial anesthesia safety efficacy for labor analgesia obstetric surgical anesthesia. As research regarding how to approach during care is limited, the aim this review familiarize anesthesiologists with anatomy, present available data, empower physicians use a pragmatic