A5056237987- HIV/AIDS Research and Interventions
- HIV, Drug Use, Sexual Risk
- HIV Research and Treatment
- Cervical Cancer and HPV Research
- HIV-related health complications and treatments
- Sex work and related issues
- Adolescent Sexual and Reproductive Health
- Global Cancer Incidence and Screening
- HIV/AIDS drug development and treatment
- Substance Abuse Treatment and Outcomes
- Health disparities and outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Hepatitis B Virus Studies
- Reproductive tract infections research
- Homelessness and Social Issues
- Hepatitis C virus research
- Cardiac Imaging and Diagnostics
- Employment and Welfare Studies
- LGBTQ Health, Identity, and Policy
- HIV/AIDS Impact and Responses
- Ethics in Clinical Research
- Lipoproteins and Cardiovascular Health
- Opioid Use Disorder Treatment
- Patient-Provider Communication in Healthcare
- Cardiovascular Disease and Adiposity
Johns Hopkins University
2016-2025
Discovery Air (Canada)
2022
Johns Hopkins University Center for AIDS Research
2019-2021
Penn Center for AIDS Research
2019
University of Pennsylvania
2019
AIDS Research Consortium of Atlanta
2019
George Washington University
2019
Johns Hopkins Medicine
2019
Triangle
2010-2012
American Journal Experts (United States)
2010-2012
Antiretroviral therapy that reduces viral replication could limit the transmission of human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples.In nine countries, we enrolled 1763 couples which one partner was HIV-1-positive and other HIV-1-negative; 54% subjects were from Africa, 50% infected partners men. HIV-1-infected with CD4 counts between 350 550 cells per cubic millimeter randomly assigned a 1:1 ratio to receive antiretroviral either immediately (early therapy) or after...
An interim analysis of data from the HIV Prevention Trials Network (HPTN) 052 trial showed that antiretroviral therapy (ART) prevented more than 96% genetically linked infections caused by human immunodeficiency virus type 1 (HIV-1) in serodiscordant couples. ART was then offered to all patients with HIV-1 infection (index participants). The study included 5 years follow-up assess durability such for prevention transmission.We randomly assigned 1763 index participants receive either early or...
Context.—The US Public Health Service and the International AIDS Society–USA recently published recommendations for antiretroviral therapy (ART) persons infected with human immunodeficiency virus (HIV); however, anecdotal evidence suggests that HIV-infected injection drug users (IDUs) may not be receiving optimal care as defined by recommendations.Objective.—To assess ART use in IDUs.Design.—A cross-sectional survey of self-reported between July 1996 June 1997 IDUs.Setting.—A community-based...
Background: Human papillomavirus (HPV) type 16 is etiologically associated with approximately half of all cervical cancers. It important, therefore, to determine the characteristics that distinguish HPV16 from other HPV types. A preliminary result based on cross-sectional baseline data in Women's Interagency Immunodeficiency Virus (HIV) Study (WIHS) suggested prevalence might have a weaker association immune status HIV-seropositive women than To address this issue, we examined test results...
Objective: To determine whether HIV and sexually transmitted disease (STD) incidence rates among young men in northern Thailand have declined since the establishment of '100% Condom Program', to prospectively document changes association between behavioral risk factors incident STD infections. Setting: Thirteen military bases Thailand. Methods: Serial prospective cohorts 19–23-year-old male conscripts (n = 4086) inducted into service from six Thai provinces 1991 1993 were followed at 6-month...
During 1988 and 1989, intravenous drug users recruited through extensive community outreach efforts in Baltimore, Maryland, were interviewed about injection sex practices the prior 11 years, with screening for antibody to human Immunodeficiency virus type 1 (HIV-1). Neither interviewers nor subjects aware of HIV-1 serostatus until 2 weeks after interview. Among 2,616 who last injected drugs within same calendar year as screening, seroprevalence was 30.1% those any use shooting galleries,...
The key objectives of this study were to examine whether HIV infection itself is associated with subclinical coronary atherosclerosis and the potential contributions cocaine use antiretroviral therapies (ARTs) artery disease (CAD) in HIV-infected persons.Between June 2004 February 2015, 1429 African American (AA) adults with/without Baltimore, Maryland, enrolled an observational effects infection, exposure ART, on CAD. prevalence was 30.0% HIV-uninfected 33.7% (P=0.17). Stratified analyses...
Summary: Sharing of contaminated needles constitutes one the primary modes HIV transmission in U.S. This study examined social and environmental factors as possible correlates needle sharing a sample innercity drug users Baltimore, Maryland. Drug users' context was assessed through an anlysis personal networks, use delineation injection settings. The 330 respondents participating prevention were administered two surveys average 5.2 months apart. An examination association network...
OBJECTIVES: This study investigated hepatitis B immunization coverage and the extent of virus (HBV) infection among young men who have sex with (MSM), a group for whom vaccine has been recommended since 1982. METHODS: We analyzed data from 3432 MSM, aged 15 to 22 years, randomly sampled at 194 gay-identified venues in 7 US metropolitan areas 1994 through 1998. Participants were interviewed, counseled, tested serologic markers HBV infection. RESULTS: Immunization was 9% prevalence 11%. ranged...
The provision of appropriate HIV prevention, treatment, and care services for most-at-risk populations (MARP) will challenge many health systems. For people who sell sex or inject drugs men have with men, stigma, discrimination, criminalization can limit access to care, inhibit service uptake, reduce the disclosure risks. Several models MARP may address these issues. We discuss integrated models, stand-alone services, hybrid which be some in settings. Both public human rights frameworks...
Background. FIB-4 represents a noninvasive, composite index that is validated measure of hepatic fibrosis, which an important indicator liver disease. To date, there are limited data regarding fibrosis in women. Methods. was evaluated cohort 1227 women, and associations were univariate multivariate regression models among 4 groups subjects classified by their human immunodeficiency virus (HIV) hepatitis C (HCV) infection status. Results. The median scores 0.60 HIV-/HCV- 0.83 HIV-/HCV+ 0.86...
Abstract Recent research has implicated economic insecurity in increasing midlife death rates and “deaths of despair,” including suicide, chronic liver disease, drug alcohol poisoning. In this ecological longitudinal study, we evaluated the association between changes increases deaths despair all-cause mortality US counties during 2000–2015. We extended a previously developed measure using indicators from Census Federal Reserve Bank for years 2000 2010. Linear regression models were used to...
Objective To assess whether initiation of highly active antiretroviral therapy (HAART) is associated with a subsequent resumption sexual and drug use risk behaviors. Methods Within an ongoing prospective study HIV-seropositive injection users (IDUs), subsample at least one CD4 cell count < 500 × 106 cells/l after 1996 (when HAART became available) three consecutive visits were selected for analysis. Patients underwent semi-annual interviews behaviors reports medication use. Data from...
In a nationally representative sample of sexually experienced youths aged 14-22, 37% young women and 52% men said the condom was primary method used to prevent pregnancy at last intercourse; an additional 8% 7%, respectively, they much this represents dual use [corrected]. Condom intercourse reported by 25% whose partner using pill. Significant independent predictors with pill among included younger age, black race, engaging in fewer nonsexual risk behaviors having received instruction about...
HIV-1 subtype B and CRF01_AE have been in circulation Thailand Southeast Asia for more than a decade. Initially separated by risk group, the two strains are increasingly intermixed, recombinant of essentially reciprocal structure recently reported. Here we identify additional CRF_01B recombinants provide evidence that now pass freely between high-risk populations. HIV isolates showed discordance multi-region genotyping assays were selected study. They drawn from 3 different cohorts...
A theoretical model was used to examine the influence of relationship factors, pregnancy intentions, contraceptive behavior and other psychosocial characteristics on stages change in condom use among heterosexual black women reproductive age. Data from an inner-city street survey compared who were not contemplating use, attempting condoms or had them consistently for short periods time, those achieved long-term consistent use. Women's with their main partner appears be important factor...
Of 308 Baltimore, Maryland women surveyed by telephone, 76.3 per cent reported having performed breast self-examination (BSE) during the last year, with only 35 reporting monthly BSE. Four BSE ability scores showed that most had little knowledge of proper technique. Utilization factors, socioeconomic status, and knowledge/attitude about cancer were not related to competency. Higher competency performing at recommended interval, been taught procedure a health professional, perceived...
Cetontano, D. (Johns Hopkins U. School of Hygiene and Public Health, Baltimore, MD 21205), A. C. Kiassen, S. Weisman, N. B. Rosenshein. The role contraceptive use in cervical cancer the Maryland Cervical Cancer Case-Control Study. Am J Epidemiol 1987;126:592–604. Recent evidence on importance sexual history sexually transmissible agents has been reported. Case-control studies have frequently demonstrated increased risk for women using oral contraceptives, while laboratory results shown that...