A5056282331- Sperm and Testicular Function
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Sexual function and dysfunction studies
- Hormonal and reproductive studies
- Sexuality, Behavior, and Technology
- Reproductive Health and Technologies
- Male Reproductive Health Studies
- Urinary Bladder and Prostate Research
- Sexual Differentiation and Disorders
- RNA Research and Splicing
- Testicular diseases and treatments
- Reproductive System and Pregnancy
- Vector-Borne Animal Diseases
- Nutrition, Genetics, and Disease
- Chromosomal and Genetic Variations
- Genital Health and Disease
- Ovarian function and disorders
- Animal Virus Infections Studies
- MicroRNA in disease regulation
- Animal Genetics and Reproduction
- Cancer-related molecular mechanisms research
- Digestive system and related health
- Genomics and Chromatin Dynamics
- Reproductive Biology and Fertility
Puigvert Foundation
2013-2024
Universitat Autònoma de Barcelona
2013-2024
University of Ferrara
2021
University of Milan
2019-2021
ASST Fatebenefratelli Sacco
2021
Ospedale Maggiore
2019-2021
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
2019-2021
Universitat de Barcelona
2021
University of Bologna
2019
Hospital de Clínicas de Porto Alegre
2019
A retrospective observational study was undertaken to gain new insight into the relationship between total testicular volume and levels of serum testosterone, luteinising hormone, follicle-stimulating prolactin clinical variables. 312 men with sexual dysfunction or infertility were divided groups B (156 each) on basis basal plasma testosterone ≤5 nmol/L ≥12 respectively. Group subclassified in A1 (primary hypogonadism) A2 (secondary hypogonadism). There significant differences group (15.33 ±...
Abstract Background A recent meta‐analysis ( Human Reproduction Update 23, 2017 and 265) reported positive sperm retrieval rates (SRR) in 50% of patients with Klinefelter syndrome (KS) undergoing testicular extraction (TESE). However, these results do not reflect the SR that we observe clinical practice. We assessed rate potential predictors real‐life setting. Materials Methods reviewed data 103 KS men who underwent TESE between 08/2008 03/2019 at five tertiary referral Andrology centers....
Severe spermatogenic failure (SpF) represents the most extreme manifestation of male infertility, as it decreases drastically semen quality leading to either severe oligospermia (SO, <5 million spermatozoa/mL semen) or non-obstructive azoospermia (NOA, complete lack spermatozoa in ejaculate without obstructive causes).The main objective present study is analyze Iberian population effect 6 single-nucleotide polymorphisms (SNPs) previously associated with NOA Han Chinese through genome-wide...
Abstract We conducted a genome-wide association study in large population of infertile men due to unexplained spermatogenic failure (SPGF). More than seven million genetic variants were analysed 1,274 SPGF cases and 1,951 unaffected controls from two independent European cohorts. Two genomic regions associated with the most severe histological pattern SPGF, defined by Sertoli cell-only (SCO) phenotype, namely MHC class II gene HLA-DRB1 (rs1136759, P = 1.32E-08, OR 1.80) an upstream locus...
The exact mechanism of varicocele-related infertility is still elusive, therefore, the current challenges for its management lie in determining which patients stand to benefit most from surgical correction. authors aimed assess clinical factors affecting semen improvement after left microsurgical subinguinal varicocelectomy (MSV) relation patient age, ultrasound varicocele grading (USVG), and presence a right subclinical (RSV).From 2010 2017 total 228 infertile underwent MSV varicocele....
Previous studies in animal models evidenced that genetic mutations of KATNAL1, resulting dysfunction its encoded protein, lead to male infertility through disruption microtubule remodelling and premature germ cell exfoliation. Subsequent humans also suggested a possible role KATNAL1 single-nucleotide polymorphisms the development as consequence severe spermatogenic failure.The main objective present study is evaluate effect common variation large phenotypically well-characterised cohort...
Adult patients with Klinefelter syndrome (KS) may present testicular volume loss and a decrease in circulating testosterone (T) levels. However, the actual rate of hypogonadism adult KS men is unknown. We aimed to (a) assess prevalence different forms cohort non-obstructive azoospermia (NOA); (b) investigate potential preoperative predictor positive sperm retrieval (SR) at surgery same men.Complete data from 103 NOA who underwent extraction (TESE) between 2008 2019 five centers were...
Infertility is a growing concern in developed societies. Two extreme phenotypes of male infertility are non-obstructive azoospermia (NOA) and severe oligospermia (SO), which characterized by spermatogenic failure (SpF). We designed genetic association study comprising 725 Iberian infertile men as consequence SpF 1058 unaffected controls to evaluate whether five single-nucleotide polymorphisms (SNPs), previously associated with reduced fertility Hutterites, also involved the susceptibility...
We aimed to evaluate ten-year outcomes of penile prosthesis (PP) implantation for the treatment erectile dysfunction and assess predictors early prosthetic infection (EPI). identified 549 men who underwent 576 PP placements between 2008 2018. Univariate multivariate analyses were used identify potential EPI. An EPI predictive nomogram was developed. Thirty-five (6.1%) cases recorded with an explant rate 3.1%. In terms satisfaction, 82.0% patients defined themselves as "satisfied," while...
Small RNA-sequencing (small RNA-seq) has revealed the presence of small RNA-naturally occurring variants such as microRNA (miRNA) isoforms or isomiRs. Due to their size and sequence similarity among miRNA isoforms, validation by RT-qPCR is challenging. We previously identified two miR-31-5p isomiRs-the canonical a 3'isomiR variant (3' G addition)-which were differentially expressed between individuals with azoospermia different origin. Here, we sought determine discriminatory capacity these...
Erectile dysfunction (ED) can stem from various organic and functional causes but is often linked to vascular health cardiovascular disease. Limited data exist on how disease markers correlate with objective ED tests like the Nocturnal Penile Tumescence Rigidity (NPTR) test Color Doppler Ultrasound (PCDU).
Background: Severe spermatogenic failure (SPGF) represents one of the most relevant causes male infertility. This pathological condition can lead to extreme abnormalities in seminal sperm count, such as severe oligozoospermia (SO) or non-obstructive azoospermia (NOA). Most cases SPGF have an unknown aetiology, and it is known that this idiopathic form infertility a complex condition. In study, we aimed evaluate whether common genetic variation TEX15, which encodes key player spermatogenesis,...
You have accessJournal of UrologySexual Function/Dysfunction: Medical, Hormonal & Non-surgical Therapy I1 Apr 2017MP91-01 ELECTROHYDRAULIC LOW-INTENSITY SHOCKWAVE THERAPY FOR PDE5I-REFRACTORY ERECTILE DYSFUNCTION: A PROSPECTIVE, RANDOMIZED, PLACEBO-CONTROLLED STUDY Jose Vinay, Daniel Moreno, Alvaro Vives, Osvaldo Rajmil, Eduardo Ruiz-Castane, and Josvany Sanchez-Curbelo VinayJose Vinay More articles by this author , MorenoDaniel Moreno VivesAlvaro Vives RajmilOsvaldo Rajmil...
You have accessJournal of UrologySexual Function/Dysfunction: Medical, Hormonal & Non-surgical Therapy I (PD21)1 Apr 2019PD21-06 PENILE LOW INTENSITY SHOCK WAVE TREATMENT FOR PDE5I REFRACTORY ERECTILE DYSFUNCTION: A RANDOMIZED SHAM-CONTROLLED CLINICAL TRIAL Jose Vinay*, Daniel Moreno, Osvaldo Rajmil, Eduardo Ruiz-Castañe, and Josvany Sanchez-Curbelo Vinay*Jose Vinay* More articles by this author , MorenoDaniel Moreno RajmilOsvaldo Rajmil Ruiz-CastañeEduardo Ruiz-Castañe...