Xinxin Zhang

ORCID: 0000-0002-6508-6816
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Research Areas
  • MRI in cancer diagnosis
  • SARS-CoV-2 and COVID-19 Research
  • Head and Neck Cancer Studies
  • COVID-19 Clinical Research Studies
  • Systemic Lupus Erythematosus Research
  • Advanced MRI Techniques and Applications
  • SARS-CoV-2 detection and testing
  • Prostate Cancer Diagnosis and Treatment
  • Liver Diseases and Immunity
  • Bladder and Urothelial Cancer Treatments
  • Cardiovascular Health and Disease Prevention
  • Liver Disease Diagnosis and Treatment
  • Neurological Disease Mechanisms and Treatments
  • Renal Diseases and Glomerulopathies
  • Esophageal Cancer Research and Treatment
  • Lung Cancer Research Studies
  • Reproductive System and Pregnancy
  • Management of metastatic bone disease
  • Bone health and treatments
  • Cardiovascular Disease and Adiposity
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Asthma and respiratory diseases
  • Salivary Gland Tumors Diagnosis and Treatment
  • Salivary Gland Disorders and Functions
  • Allergic Rhinitis and Sensitization

The First Affiliated Hospital, Sun Yat-sen University
2024-2025

Sun Yat-sen University
2024-2025

Gansu University of Traditional Chinese Medicine
2023-2024

Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2024

Chinese PLA General Hospital
2017-2024

Tianjin Medical University General Hospital
2020

X-Fab (Germany)
2015

Abstract Background and aim Two oral antivirals (Nirmatrelvir- ritonavir Azvudine) are widely used in China practice during the Omicron wave of pandemic. However, little evidence regarding real-world effectiveness these two in-hospital patients. We aimed to evaluate clinical nirmatrelvir-ritonavir versus azvudine among adult hospitalized patients with COVID-19. Methods This retrospective cohort study data from three Chinese PLA General Hospital medical centres. Hospitalized COVID-19 treated...

10.1186/s12879-023-08965-8 article EN cc-by BMC Infectious Diseases 2024-01-08

Remnant cholesterol (RC) causes inflammation and promotes kidney diseases development. However, its role in lupus nephritis (LN) remains unclear. The purpose of this study was to investigate the association between RC LN. This observational conducted among patients enrolled 2000 2018 High Quality Evidence Guangzhou Lupus Nephritis Cohort. outcomes were defined as adverse renal outcomes, including serum creatinine doubled end-stage disease. Patients stratified into lower higher groups based...

10.1186/s12944-025-02503-y article EN cc-by-nc-nd Lipids in Health and Disease 2025-04-10

Objective. This study aimed to analyze the effects of comprehensive protection bilateral parotid glands (PG-T), contralateral submandibular gland (cSMG), and accessory salivary in oral cavity (OC) by helical tomotherapy for head-and-neck cancer patients. Methods . Totally 175 patients with histologically confirmed treated were recruited. The doses delivered PG-T, cSMG, OC constrained be as low possible treatment planning. saliva flow rates xerostomia questionnaire evaluated. Correlation...

10.1155/2019/2401743 article EN BioMed Research International 2019-07-14

Background The effectiveness of nirmatrelvir–ritonavir has mainly been shown in non-hospitalized patients with mild-to-moderate coronavirus disease 2019 (COVID-19). real-world nirmatrelvir-ritonavir urgently needs to be determined using representative in-hospital COVID-19 during the Omicron wave pandemic.

10.1080/07853890.2024.2313062 article EN cc-by-nc Annals of Medicine 2024-02-14

Intima-media thickness is a non-invasive arterial marker of early-stage atherosclerosis. Identifying carotid plaque superior surrogate endpoint for assessing atherosclerotic lesions. The aim this study was to investigate the association intima-media (CIMT) and with lipids among asymptomatic low-income rural residents in China. A total 3,789 people aged ≥45 years without history stroke or cardiovascular disease were recruited study. B-mode ultrasonography performed measure CIMT identify early...

10.3389/fneur.2020.00276 article EN cc-by Frontiers in Neurology 2020-04-24

Abstract Background: Clinical effectiveness of Azvudine against coronavirus infection and optimal time for initiation treatment to hospitalized COVID-19 patients are not fully understood. Methods: This is a multi-center retrospective cohort study, five clinical centers the Chinese People’s Liberation Army General Hospital participated. From omicron pandemics, 6218 confirmed with from December 10, 2022, February 20, 2023, were retrieved this study. After exclusions propensity score matching ,...

10.21203/rs.3.rs-3145554/v1 preprint EN cc-by Research Square (Research Square) 2023-07-14

Abstract Objectives To investigate whether reduced field-of-view (rFOV) diffusion-weighted imaging (DWI) with deep learning reconstruction (DLR) can improve the accuracy of evaluating muscle invasion using VI-RADS. Methods Eighty-six bladder cancer participants who were evaluated by conventional full (fFOV) DWI, standard rFOV (rFOV STA ) and fast DLR DWI included in this prospective study. Tumors categorized according to vesical reporting data system (VI-RADS). Qualitative image quality...

10.1186/s13244-024-01686-9 article EN cc-by Insights into Imaging 2024-06-09

Using propensity score matching method (PSM) to evaluate the feasibility and clinical outcomes of simultaneous modulated accelerated radiation therapy (SMART) using helical tomotherapy (HT) in patients with nasopharyngeal carcinoma (NPC). Between August 2007 January 2016, 381 newly diagnosed NPC HT were enrolled pre-PSM cohort, including 161 cases a prospective phase II study (P67.5 study, prescription dose 67.5Gy 30 fractions primary tumour positive lymph nodes) 220 retrospective (P70 70Gy...

10.1186/s12885-017-3581-1 article EN cc-by BMC Cancer 2017-08-29

Narrow-band imaging (NBI) endoscopy is used in various tumor detection and important detecting early tumors. To explore the application value of NBI diagnosing pharyngeal Ninety-one patients with masses who attended Department Otorhinolaryngology, Head Neck Surgery Gansu Provincial Hospital from January 2023 to February 2024 were selected, white light (WL) applied examine pharynx relationship between two was observed. SPSS 25.0 software for statistical analysis. The sensitivity laryngeal...

10.1016/j.amjoto.2024.104296 article EN cc-by-nc-nd American Journal of Otolaryngology 2024-04-16

<title>Abstract</title> <bold>Objective: </bold>To evaluate the prognostic importance of sex in lupus nephritis (LN). <bold>Methods: </bold>A retrospective cohort 921 biopsy-confirmed LN patients, diagnosed between 1996 and 2018, was analyzed. Demographics, clinical characteristics, laboratory findings, renal pathology were assessed. The primary outcome mortality, secondary outcomes included doubling serum creatinine end-stage disease (ESRD). Sex-associated risks evaluated using Cox...

10.21203/rs.3.rs-4554592/v1 preprint EN Research Square (Research Square) 2024-07-02

In this prospective study, feasibility of deep learning reconstruction (DLR) in axial FSE-T2WI and reduced-FOV DWI (FOCUS DWI) were evaluated compared with standard protocols. Fast protocol DLR substantially reduced scanning time (axial FSE-T2WI: -32.1%; FOCUS-DWI: -36.8%). FOCUS showed the highest SNR CNR for prostate PZ, TZ lesion. PZ TZ. Moreover, fast FOCUS-DWI demonstrated equivalent or better image quality than images. may be useful multiparametric MRI optimization high-quality acquisition.

10.58530/2023/3705 article EN Proceedings on CD-ROM - International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition/Proceedings of the International Society for Magnetic Resonance in Medicine, Scientific Meeting and Exhibition 2024-08-14

To evaluate the prognostic importance of sex in lupus nephritis (LN).

10.1186/s40001-024-02089-8 article EN cc-by-nc-nd European journal of medical research 2024-10-18

Abstract OBJECTIVE To systematically evaluate the efficacy and safety of montelukast sodium combined with budesonide nasal spray in treatment allergic rhinitis. METHODS Databases such as China Biomedical Literature Database, Knowledge Network, Wanfang VIP Embase, Cochrane Library, Pubmed, Web Of Science were searched. Randomized controlled trials evaluating combination for rhinitis included to be searched from date database construction March 18, 2023. Meta-analysis was performed using...

10.21203/rs.3.rs-2837640/v1 preprint EN cc-by Research Square (Research Square) 2023-05-10
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