A5100656842- Head and Neck Cancer Studies
- Advanced MRI Techniques and Applications
- MRI in cancer diagnosis
- Acute Ischemic Stroke Management
- Head and Neck Surgical Oncology
- Cerebrovascular and Carotid Artery Diseases
- Radiomics and Machine Learning in Medical Imaging
- Monoclonal and Polyclonal Antibodies Research
- Advanced Neuroimaging Techniques and Applications
- Hepatocellular Carcinoma Treatment and Prognosis
- Esophageal Cancer Research and Treatment
- Glioma Diagnosis and Treatment
- Liver Disease Diagnosis and Treatment
- HER2/EGFR in Cancer Research
- Dental Trauma and Treatments
- Endodontics and Root Canal Treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Lung Cancer Diagnosis and Treatment
- Cancer Diagnosis and Treatment
- Dental materials and restorations
- Oral and Maxillofacial Pathology
- Ear and Head Tumors
- Colorectal Cancer Screening and Detection
- Dental Radiography and Imaging
- Parathyroid Disorders and Treatments
Beijing Jishuitan Hospital
2025
Capital Medical University
2025
Peking University
2025
117th Hospital of People's Liberation Army
2024
Chinese People's Liberation Army
2008-2024
Tianjin Huanhu Hospital
2015-2023
Chinese PLA General Hospital
2011-2022
Sichuan University
2012-2022
West China Hospital of Sichuan University
2012-2022
Weatherford College
2022
Objectives The measurement of visceral fat (VF) is clinically important for the identification individuals at high risk obesity-related health conditions. Bioelectrical impedance analysis (BIA) a widely available and frequently used body composition assessment method, but there have been few validation studies VF. This study investigated agreement between BIA CT VF in adults. Design Cross-sectional study. Setting Between 2015 2016 China. Participants A total 414 adults (119 men 295 women)...
Purpose To investigate the use of stiffness value and ratio (ratio lesion to background liver parenchyma values) discriminate malignant from benign focal lesions by using histologic results as reference standard. Materials Methods This study was approved institutional review board, written informed consent obtained. Three hundred seventy-three patients with proven at examination underwent measurement elastography point quantification. First, values in two regions (at 0.5–2 cm >2 periphery)...
Patients with multiple sclerosis (MS) commonly exhibit cognitive impairments (CI). However, the neural mechanisms underlying CI remain unclear. The current study applied diffusion tensor imaging (DTI) and voxel-based morphometric (VBM) magnetic resonance (MRI) techniques to evaluate differences in white matter (WM) integrity gray (GM) volume between MS patients preservation (CP). Neuropsychological assessment MRI were obtained from 39 relapsing-remitting (RRMS) 29 healthy controls (HCs)....
This study aimed to identify risk factors associated with lymph node metastasis (LNM) in early non-small-cell lung cancer (eNSCLC) patients and develop a nomogram model for individualized LNM assessment. A retrospective analysis was conducted using clinical data from 1013 eNSCLC treated at Beijing Jishuitan Hospital between January 2019 June 2024. Patients were divided into training group (668 patients), validation (345 an external (112 patients). Multivariate logistic regression performed...
Transforming growth factor (TGF)-β is involved in many physiologic processes, it often promotes metastasis, and its high expression correlated with poor prognosis. In the present study, we analyzed correlation between transforming beta 1 (TGF-β1) prognosis intrahepatic cholangiocarcinoma.We examined of TGF-β1 78 cholangiocarcinomas by immunohistochemistry clinicopathological parameters. was expressed 37 (47.4%) cholangiocarcinomas. The significantly lymph node distant tumour recurrence....
This study aimed to investigate the efficacy of induction chemotherapy followed by concurrent and helical tomotherapy in patients with T4b squamous cell carcinoma nasal cavity paranasal sinus regard orbital organ preservation quality life.Clinical data 28 cases involvement who received multimodal treatment for between May 2008 September 2015 were retrospectively analysed. The side effects assessed. included 18 male 10 female patients. All treated chemoradiotherapy and/or epidermal growth...
Abstract Purpose To determine if contrast‐enhanced (CE) MRI of intracranial lesions benefits from time‐resolved MR angiography (MRA) during contrast agent injection. Materials and Methods For 126 patients with suspected undergoing routine CE at 3.0T ( N = 88) or 1.5T 38), MRA (three‐dimensional [3D] imaging kinetics [TRICKS]) was performed injection the gadolinium (Gd) dose 0.1 mmol/kg. Time to peak (TTP) enhancement as well time internal carotid artery (ICA), middle cerebral (MCA), superior...
Maintaining a certain level of hydrogen sulfide (H2S) in ischemia-reperfusion (I/R) is essential for limiting injury to the liver. Exogenous H2S exerts protective effects against this injury, but mechanisms remain unclear. Liver was induced Wistar rats undergoing hepatic I/R 30 min, followed by 3-h reperfusion. Administration GYY4137 (a slow-releasing donor) significantly attenuated severity liver and reflected reduced inflammatory cytokine production cell apoptosis, levels which were...
Abstract Aphid saliva plays an essential role in the interaction between aphids and their host plants. Several aphid salivary proteins have been identified but none from galling aphids. Here Chinese gall are analyzed, Schlechtendalia chinensis , via LC‐MS/MS analysis. A total of 31 directly collected artificial diet, 141 extracts derived dissected glands. Among these proteins, 17 found both In comparison with ten other free‐living Hemipterans, most striking feature protein S. is existence...
Background Thymectomy is an established treatment for myasthenia gravis (MG), and video-assisted thoracoscopic surgery (VATS) thymectomy has become acceptable surgical procedure. This study aimed to compare the results of VATS open identify prognostic factors after thymectomy. Methods The clinical data 187 consecutive thymectomies performed between July 2000 December 2009 were retrospectively reviewed; 75 112 thymectomies. Clinical efficacy variables influencing outcome assessed by...
Objective. This study aimed to analyze the effects of comprehensive protection bilateral parotid glands (PG-T), contralateral submandibular gland (cSMG), and accessory salivary in oral cavity (OC) by helical tomotherapy for head-and-neck cancer patients. Methods . Totally 175 patients with histologically confirmed treated were recruited. The doses delivered PG-T, cSMG, OC constrained be as low possible treatment planning. saliva flow rates xerostomia questionnaire evaluated. Correlation...
Amphiregulin (AR) and its receptor, epidermal growth factor receptor (EGFR), were evaluated by dual immunostaining in a series of 84 invasive ductal breast carcinoma specimens, 33 which from locally advanced inflammatory (T4d) cancer. Co-expression AR EGFR was always found non-malignant tissues adjacent to tumours (24/24). Alternatively, expression epithelial tumour cells 50% 17.8% respectively. In stroma, 59.5% 30.9% respectively, positively stained. By univariate analysis, carcinomas...
The present study aimed to investigate the clinical relevance of circulating tumor cells (CTCs) in patients with locally advanced head and neck squamous cell carcinoma (LA‑HNSCC), particularly nasopharyngeal hypopharyngeal carcinoma. CTCs were isolated using negative immunomagnetic bead enrichment identified by fluorescence situ hybridization. Youden's index receiver operating characteristic (ROC) curve used select optimal CTC baseline value. χ2 test or Fisher's determine association between...
Purpose: The present clinical trial was designed to evaluate the efficacy and safety of concurrent helical tomotherapy (HT) with cetuximab followed by adjuvant chemotherapy docetaxel cisplatin (TP) in treatment patients locoregionally advanced nasopharyngeal carcinoma.Materials Methods: This phase II included 43 Stage III/IV LANC (33 III 10 IV).The consisted HT (400 mg/m 2 loading dose weekly 250mg/m ), four cycles [docetaxel (70 on Day 1) (40 Days 1 every 3 weeks).Side effects were...
Abstract Direct pulp capping is a minimally invasive method to preserve integrity. We evaluated the treatment efficacy of Er:YAG laser irradiation combined with direct for exposure due caries. A total 21 patients 22 teeth were enrolled in conventional group (calcium hydroxide), and 24 25 laser‐assisted (Er:YAG at settings 10 Hz, 50 mJ; calcium hydroxide). The cumulative success rate was 68.2% 91.7% 12 months, respectively. Results showed that procedure increased survival time (β = 0.04, OR...
Objective This study aimed to develop a least absolute shrinkage and selection operator (LASSO)-based multivariable normal tissue complication probability (NTCP) model predict radiation-induced xerostomia in patients with nasopharyngeal carcinoma (NPC) treated comprehensive salivary gland–sparing helical tomotherapy technique. Methods Materials LASSO the extended bootstrapping technique was used build NTCP models factors of patient-reported relieved by 50% 80% compared level at end radiation...
The presence of epidermal-growth-factor receptors (EGFR) and its ligands (TGFalpha amphiregulin) in breast-cancer tissues suggests that they play a paracrine/autocrine role tumor growth or progression. This hypothesis was tested on 3 cell lines, S2T2, NS2T2A NS2T2A1. These epithelial cells are derived from normal human breast-epithelial-cell culture transformed by SV40-T Ag, the same clonal origin, have respectively increasing levels EGFR, TGFalpha, amphiregulin thymidine-kinase activity...
Maintaining phosphorus balance in in-center hemodialysis (ICHD) patients is problematic despite recommended dietary restriction, dialysis, and phosphate binder use. Rarely P content prescribed medications considered, but this source should raise concern. Data was obtained from the Fresenius Kidney Care (FKC) electronic data warehouse Knowledge Center MedReview-eRx accessed Surescripts, housing > 80% of US-filled prescriptions. Adult FKC ICHD ≥ 1 medication database were analyzed (695,759...