A5043477128- Ultrasound in Clinical Applications
- Airway Management and Intubation Techniques
- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Respiratory Support and Mechanisms
- Enhanced Recovery After Surgery
- Pleural and Pulmonary Diseases
- Trauma and Emergency Care Studies
- Tracheal and airway disorders
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- COVID-19 diagnosis using AI
- Anesthesia and Pain Management
- Mechanical Circulatory Support Devices
- Emergency and Acute Care Studies
- Long-Term Effects of COVID-19
- Orthopedic Surgery and Rehabilitation
- Tendon Structure and Treatment
- Streptococcal Infections and Treatments
- Simulation-Based Education in Healthcare
- Vascular Procedures and Complications
- EU Law and Policy Analysis
- Orthopedic Infections and Treatments
- Sepsis Diagnosis and Treatment
- Intensive Care Unit Cognitive Disorders
University of Rijeka
2010-2024
Klinički Bolnički Centar Rijeka
2009-2021
University Hospital Centre Zagreb
2021
Centar za Promociju Nauke
2018
The COVID-19 pandemic is caused by the betacoronavirus SARS-CoV-2. In November 2021, Omicron variant was discovered and immediately classified as a of concern (VOC), since it shows substantially more mutations in spike protein than any previous variant, especially receptor-binding domain (RBD). We analyzed binding RBD to human angiotensin-converting enzyme-2 receptor (ACE2) ability sera from patients or vaccinees comparison Wuhan, Beta, Delta variants.
The aim of this study was to characterize the systemic cytokine signature critically ill COVID-19 patients in a high mortality setting aiming identify biomarkers severity, and explore their associations with viral loads clinical characteristics. We studied two patient cohorts from referral centre located Central Europe. were recruited during pre-alpha/alpha (November 2020 April 2021) delta (end period respectively. determined both serum bronchoalveolar SARS-CoV-2 load identified variant...
COVID-19 represents one of the greatest challenges in modern history. Its impact is most noticeable health care system, mostly due to accelerated and increased influx patients with a more severe clinical picture. These facts are increasing pressure on systems. For this reason, aim automate process diagnosis treatment. The research presented article conducted an examination possibility classifying picture patient using X-ray images convolutional neural networks. was dataset 185 that consists...
Abstract Background Lung atelectasis are nonventilated parts of lung tissue and occur as a result the collapse pulmonary parenchyma (alveoli). Various therapeutic procedures for inflating collapsed parenchyma, such bronchial aspiration and/or standard recruitment maneuvers, not always successful. Case presentation We report case 23-year-old Croatian man with parapharyngeal abscess on left side neck spreading infection in mediastinum thorax consequent major lung. The patient was mechanically...
Abstract The COVID-19 pandemic is caused by the betacoronavirus SARS-CoV-2. In November 2021, Omicron variant was discovered and classified as a of concern (VOC). shows substantially more mutations in spike protein than any previous variant, mostly receptor binding domain (RBD). We analyzed RBD to human ACE2 (hACE2) ability sera from patients or vaccinees comparison Wuhan, Beta Delta RBDs variants. All were produced insect cells. hACE2 ELISA microscale thermophoresis (MST). Similarly, 27...
While SARS-CoV-2 detection in sputum and swabs from the upper respiratory tract has been used as a diagnostic tool, virus quantification showed poor correlation to disease outcome thus, prognostic value. Although pulmonary compartment represents relevant site for viral load analysis, limited data exploring lower is available, its association clinical outcomes relatively unknown. Using bronchoalveolar lavage (BAL) serum samples, we quantified copy numbers systemic compartments of critically...
Estimation of the epidemiology curve for COVID-19 pandemic can be a very computationally challenging task. Thus far, there have been some implementations artificial intelligence (AI) methods applied to develop specific country. However, most AI generated models that are almost impossible translate into mathematical equation. In this paper, method called genetic programming (GP) algorithm is utilized symbolic expression (mathematical equation) which used estimation entire U.S. with high...
Studies assessing the dynamics and duration of antibody responses following SARS-CoV-2 infection or vaccination are an invaluable tool for schedule planning, assessment risk groups management pandemics. In this study, we developed employed ELISA assays to analyze humoral Nucleocapsid Spike proteins in vaccinated health-care workers (HCW) critically ill COVID-19 patients. Sera more than 1000 HCWs patients from Clinical Hospital Center Rijeka were tested across a one-year period, encompassing...
Objective Chest tube thoracostomy is a standard procedure for pleural fluid and air drainage. The aim of this study to compare the success rate targeted using two different techniques: wire-guided (TWG) technique classical surgical (CS) technique. Methods was performed on 153 human cadavers without documented pathology, mechanically ventilated during procedure. They were divided into groups each cadaver software generated random number assigned. TWG applied 76 CS 77 cadavers. four subgroups...
Objectives. Sudden cardiac death is a major cause of in today's world. During the minutes passing from onset arrest to arrival professional help, victim can only rely upon cardio-pulmonary resuscitation (CPR) provided by educated bystanders. Our aim was explore possibility whether short and affordable course CPR reeducation could have significant effect on skills retention quality delivered. Methods. We performed prospective randomized study that included 72 first second year medical...
To report a case of fatal toxic epidermal necrolysis associated with carvedilol treatment.Two days after the initiation treatment, 70-year old woman presented skin eruptions in form maculous rash blisters that rapidly progressed to necrolysis. Although suspected drug was withdrawn, reaction extremely rapid its development outcome.Carvedilol is not commonly TEN. our knowledge there are no cases related TEN reported literature.Because close temporal relationship between treatment and...
Background and Objectives: The COVID-19 disease has significantly burdened the healthcare system, including all units of severe patient treatment. Non-intensive care were established to rationalize capacity within Intensive Care Unit (ICU) create a unit where patients with Acute Respiratory Distress Syndrome (ARDS) could be treated non-invasive Continuous Positive Air Pressure (CPAP) outside ICU. This unicentric retrospective study aimed assess efficacy NIV Treatment in Patients fourth...
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