A5031558125- Obstructive Sleep Apnea Research
- Sleep and related disorders
- Sleep and Wakefulness Research
- Neuroscience of respiration and sleep
- Neonatal and Maternal Infections
- Streptococcal Infections and Treatments
- Pneumonia and Respiratory Infections
- Tracheal and airway disorders
- Digital Mental Health Interventions
- Nasal Surgery and Airway Studies
- Dysphagia Assessment and Management
- Restless Legs Syndrome Research
- Physical Activity and Health
- Cardiovascular and Diving-Related Complications
- Gastroesophageal reflux and treatments
- Nutritional Studies and Diet
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Body Contouring and Surgery
- Diet and metabolism studies
- Child Nutrition and Feeding Issues
- Bariatric Surgery and Outcomes
- Youth Substance Use and School Attendance
- Obesity, Physical Activity, Diet
- Studies on Chitinases and Chitosanases
- Sleep and Work-Related Fatigue
Reykjavík University
2011-2024
National University Hospital of Iceland
2011-2021
University of Iceland
2011-2020
Although commonly observed in clinical practice, the heterogeneity of obstructive sleep apnoea (OSA) presentation has not been formally characterised. This study was first to apply cluster analysis identify subtypes patients with OSA who experience distinct combinations symptoms and comorbidities. An baseline data from Icelandic Sleep Apnoea Cohort (822 newly diagnosed moderate-to-severe OSA) performed. Three clusters were identified. They classified as "disturbed group" (cluster 1),...
The aim was to assess the prevalence of obstructive sleep apnoea (OSA) as defined by an apnoea–hypopnea index (AHI) ≥15 in middle-aged general population, and interrelationship between OSA, sleep-related symptoms, sleepiness vigilance. A population sample 40–65-year-old Icelanders invited participate a study protocol that included type 3 study, questionnaire psychomotor vigilance test (PVT). Among 415 subjects 56.9% had no OSA (AHI <5), 24.1% mild 5–14.9), 12.5% moderate 15–29.9), 2.9%...
To assess the changes of insomnia symptoms among patients with obstructive sleep apnea (OSA) from starting treatment positive airway pressure (PAP) to a 2-y follow-up.
Distinct clinical phenotypes of obstructive sleep apnea (OSA) have been identified: Disturbed Sleep, Minimally Symptomatic, and Sleepy. Determining whether these respond differently to standard treatment helps us create a foundation for personalized therapies. We compared responses positive airway pressure (PAP) therapy in OSA phenotypes. The study sample included 706 patients from the Icelandic Sleep Apnea Cohort with moderate-to-severe who were prescribed PAP. Linear logistic mixed models...
Objectives To explore the relationship between physical activity over a 10-year period and current symptoms of insomnia, daytime sleepiness estimated sleep duration in adults aged 39–67. Design Population-based, multicentre cohort study. Setting 21 centres nine European countries. Methods Included were 4339 participants third follow-up to Community Respiratory Health Survey (ECRHS III), who answered questions on at baseline II) activity, insomnia symptoms, III). Participants reported that...
Summary Insomnia and obstructive sleep apnea (OSA) often coexist, but the nature of their relationship is unclear. The aims this study were to compare prevalence initial middle insomnia between OSA patients controls from general population as well influence on sleepiness quality life in patients. Two groups compared, untreated ( n = 824) ≥ 40 years Iceland 762). All subjects answered same questionnaires health underwent a study. Altogether, 53% males compared 81% Difficulties maintaining...
Summary Obstructive sleep apnea leads to recurrent arousals from sleep, oxygen desaturations, daytime sleepiness and fatigue. This can have an adverse impact on quality of life. The aims this study were compare: (i) life between the general population untreated patients with obstructive apnea; (ii) changes among after 2 years positive airway pressure treatment adherent non‐users. Propensity score methodologies used in order minimize selection bias strengthen causal inferences. enrolled...
Abstract Many different subjective tools are being used to measure excessive daytime sleepiness (EDS) but the most widely is Epworth Sleepiness Scale (ESS). However, it unclear if using ESS adequate on its own when assessing EDS. The aim of this study was estimate characteristics and prevalence EDS Basic Nordic Sleep Questionnaire (BNSQ) in general population samples. Participants aged 40 years older answered questions about sleepiness, health, sleep‐related symptoms quality life. Two groups...
Summary Several studies have indicated a high degree of overlap between insomnia and obstructive sleep apnoea, but little is known regarding how the may affect adverse outcomes associated with each disorders. The aim current study was to examine separate combined effects symptoms apnoea on long‐term sick leave. We used an historical cohort design 4 years follow‐up. Information leave obtained from N orwegian official registry data, merged health information H ordaland ealth S tudy in western...
Study Objectives:The aims of this study were: (1) to use a standardized psychiatric interview, conducted by trained psychologist assess the prevalence depression among patients with untreated OSA, and (2) identify if OSA severity or other comorbid disorders (insomnia, hypertension, diabetes) are related OSA.Methods: Participants were newly diagnosed (n = 284) waiting start positive airway pressure (PAP) treatment.The Mini International Neuropsychiatric Interview (MINI) was used...
<h3>Objectives</h3> To estimate the prevalence and characteristics of frequent nocturnal sweating in obstructive sleep apnoea (OSA) patients compared with general population evaluate possible changes positive airway pressure (PAP) treatment. Nocturnal can be very bothersome to patient bed partner. <h3>Design</h3> Case–control longitudinal cohort study. <h3>Setting</h3> Landspitali—The National University Hospital, Iceland. <h3>Participants</h3> The Icelandic Sleep Apnea Cohort consisted 822...
Summary The prevalence and consequences of nasal obstruction in untreated obstructive sleep apnea patients are not known. study objectives were to investigate the frequency subjective objective associations with quality life. Patients Icelandic Sleep Apnea Cohort subjected a type 3 study, answered questionnaires had their dimensions measured by acoustic rhinometry. In total, 810 participated (including 153 females), aged 54.5 ± 10.6 years [mean standard deviation (SD)] an apnea/hypopnea...
Summary The objective of this study was to evaluate the determinants long‐term adherence positive airway pressure treatment among patients with obstructive sleep apnea, special emphasis on who stop within 1 year. This is a prospective follow‐up subjects in Icelandic Sleep Apnea Cohort were diagnosed apnea between 2005 and 2009, started treatment. In October 2014, obtained by systematically evaluating available clinical files ( n = 796; 644 males, 152 females) moderate severe (apnea–hypopnea...
Group B streptococci (GBS) may cause life-threatening invasive infections in infants. The incidence of these has been increasing during the last decades. aim study was to determine epidemiology neonatal GBS be able implement therapeutic and preventive measures more effectively.A retrospective case conducted Iceland that included all neonates with positive cultures from blood or cerebrospinal fluid period 1975 2006. Serotyping available isolates performed.A total 87 children 89 were study. In...
Sleep length has been associated with obesity and various adverse health outcomes. The possible association of sleep respiratory symptoms not previously described. aim this study was to investigate the between whether such an existed independent obesity.This is a multicentre, cross-sectional, population-based performed in 23 centres 10 different countries. Participants (n=5079, 52.3% males) were adults third follow-up European Community Respiratory Health Survey III. mean±SD age 54.2±7.1...
Despite a risk-based peripartum chemoprophylaxis approach in Iceland since 1996, Streptococcus agalactiae [group B streptococci (GBS)] remains an important cause of early-onset [<7 days, disease (EOD)] and late-onset (LOD; 7 days to 3 months).We studied GBS invasive children <1 year 1976-2015. Bacteria (n = 98) were characterized by susceptibility panel antimicrobials, capsular serotyping, resistance genes, surface protein pilus-locus profiling multilocus sequence typing.Both EOD LOD...
Abstract We hypothesized that positive airway pressure treatment would induce nasal obstruction and decrease cavity due to mucosal swelling. further subjective objective at baseline negatively affect adherence. A total of 728 patients with sleep apnea were investigated in the Icelandic Sleep Apnea Cohort 2 years after starting pressure. Patients underwent home testing baseline. Questionnaires answered acoustic rhinometry was completed follow‐up. The proportion reporting nocturnal reduced...
The inflammatory markers chitinase-3-like protein 1 (CHI3L1) and chitotriosidase (CHIT1) have both been associated with cardiovascular complications. aim of this preliminary observational study was to assess the roles interaction obstructive sleep apnea (OSA) severity body mass index (BMI) plasma CHI3L1 levels CHIT1 activity in patients moderate severe OSA. second positive airway pressure (PAP) treatment BMI on expression same proteins. included 97 OSA an apnea–hypopnea (AHI) ≥ 15 full usage...
Objectives To compare the prevalence of different insomnia subtypes among middle-aged adults from Europe and Australia to explore cross-sectional relationship between subtypes, respiratory symptoms lung function. Design Cross-sectional population-based, multicentre cohort study. Setting 23 centres in 10 European countries Australia. Methods We included 5800 participants third follow-up Community Respiratory Health Survey III (ECRHS III) who answered three questions on symptoms: difficulties...
Introduction. Group B streptococcus (GBS) is a leading cause of invasive neonatal infections. These have been divided into early-onset disease (EOD; <7 days) and late-onset (LOD; 7–89 days), with different GBS clonal complexes (CCs) associated presentations. Hypothesis. Different CCs are timing infection (EOD or LOD) clinical presentation (sepsis, meningitis pneumonia). Aim. To study infant infections in Iceland from 1975 to 2019. Are specific related presentation? Is CC17 overrepresented...
Insomnia is a common health problem with serious mental and physical consequences as well increased economical costs. The use of hypnotics in Iceland immense spite cognitive behavioral therapy for insomnia (CBT-I) being recommended the first choice treatment chronic insomnia. To meet needs more individuals suffering from insomnia, online CBT-I was established at betrisvefn.is. objective this research to evaluate effectiveness internet-based CBT-I.One hundred seventy-five users (mean age 46 y...