A5004602195- Obstructive Sleep Apnea Research
- Cardiovascular and Diving-Related Complications
- Neuroscience of respiration and sleep
- Tracheal and airway disorders
- Respiratory Support and Mechanisms
- Airway Management and Intubation Techniques
- Cardiac Valve Diseases and Treatments
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Occupational exposure and asthma
- Venous Thromboembolism Diagnosis and Management
- Occupational and environmental lung diseases
- Atrial Fibrillation Management and Outcomes
- Medical Imaging and Pathology Studies
- Cardiac Arrhythmias and Treatments
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Advanced Software Engineering Methodologies
- Autoimmune Bullous Skin Diseases
- Central Venous Catheters and Hemodialysis
- Sleep and related disorders
- Tuberculosis Research and Epidemiology
- Anesthesia and Pain Management
- Neuroblastoma Research and Treatments
- Indoor Air Quality and Microbial Exposure
- Anesthesia and Sedative Agents
- Pleural and Pulmonary Diseases
Hospital General Universitario de Albacete
1997-2024
Antenor Orrego Private University
2024
Complejo Hospitalario Universitario de Albacete
2013-2024
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
2019
Biomedical Research Institute of Lleida
2019
Hospital Universitari Arnau de Vilanova
2019
Clínica Las Condes
2017-2018
University of Chile
2017
Duke Medical Center
2016
Vall d'Hebron Hospital Universitari
1994-1997
Background Hypoxic burden (HB) has emerged as a strong predictor of cardiovascular risk in obstructive sleep apnoea (OSA). We aimed to assess the potential HB predict benefit treating OSA with continuous positive airway pressure (CPAP). Methods This was post hoc analysis ISAACC trial ( ClinicalTrials.gov : NCT01335087 ) including non-sleepy patients acute coronary syndrome (ACS) diagnosed (apnoea–hypopnoea index ≥15 events·h −1 by respiratory polygraphy. Patients were randomised CPAP or...
Rationale: Obstructive sleep apnea (OSA) is associated with increased cardiovascular disease (CVD) risk. Conversely, OSA has not been shown to increase recurrent events in patients acute coronary syndrome (ACS). This lack of homogeneity could suggest that the deleterious effect and its contribution CVD depend on specific patient profiles.Objectives: To evaluate risk for different ACS phenotypes.Methods:Post hoc analysis ISAACC (Continuous Positive Airway Pressure Patients OSA) study,...
Rationale: Obstructive sleep apnea (OSA) is prevalent in patients with acute coronary syndrome (ACS) and a cause of secondary hypertension. Objectives: To explore the long-term effects OSA continuous positive airway pressure (CPAP) treatment on blood (BP) ACS. Methods: Post hoc analysis ISAACC study (Continuous Positive Airway Pressure Patients Acute Coronary Syndrome Sleep Apnea; NCT01335087) included 1,803 admitted for (apnea–hypopnea index [AHI], ⩾15 events/h) were randomly assigned to...
According to recent epidemiologic studies, patients with sleep apnea/hypopnea syndrome (SAHS) are at increased risk of cardiovascular diseases, including stroke. However, the mechanisms not well defined. Nocturnal apneas can trigger acute cerebral ischemia in predisposed and impaired vasodilatation is present SAHS, but few studies have explored vascular dysfunction often gave inconclusive results. The aims our study were assess whether SAHS impairment hemodynamics respect controls,...
Sleep length has been associated with obesity and various adverse health outcomes. The possible association of sleep respiratory symptoms not previously described. aim this study was to investigate the between whether such an existed independent obesity.This is a multicentre, cross-sectional, population-based performed in 23 centres 10 different countries. Participants (n=5079, 52.3% males) were adults third follow-up European Community Respiratory Health Survey III. mean±SD age 54.2±7.1...
Secondary sicca syndrome has been described in silicotic and exposed nonpneumoconiotic individuals. Systemic autoimmune pathogenic mechanisms have thought to be responsible. Salivary gland mineral deposition not so far implicated. We describe the case of a dental technician who sand-blasted prostheses developed silicoproteinosis syndrome. Immunological studies were negative. Scanning electron microscopy study energy-dispersive X-ray analysis carried out patient's lung salivary two glands...
Obstructive sleep apnoea (OSA) is highly prevalent in children and a major public health problem. An attempt made to determine the clinical polysomnographic presentation of paediatric OSA our area. Retrospective descriptive study tests conducted on up 14 years old from 1999 2012 Sleep Unit University Hospital Albacete. Age, gender, anthropometric, data, indication variables study, treatment, outcomes were collected. The included 234 children. was found 71.8%, with 42.3% moderate 44.6%...
Obstructive sleep apnea syndrome (OSAS) is characterized in polysomnography by recurrent airflow obstruction during sleep. The underlying pathogenic mechanisms of neuropsychological and cerebrovascular events patients with OSAS have not been clarified unequivocally.Case-control study to evaluate the cerebral vasomotor reactivity assessed breath-holding maneuver at basilar artery compared control subjects.The included 76 controls. Vascular risk factors (arterial hypertension, diabetes...
Obstructive sleep apnea (OSA) is associated with a recurrent cardiovascular event (CVE) risk in patients first acute coronary syndrome (ACS). However, the pathological pathways by which OSA promotes this deleterious role are unknown. We aim to explore proteomic profile that promote CVE severe ACS without previous diseases.This post-hoc analysis from ISAACC study (NCT01335087) included 86 admitted for ACS. Patients underwent respiratory polygraphy 24-72 h diagnosis. analyzed of 276 and...
El síndrome de apneas-hipopneas del sueño (SAHS) es altamente prevalente en la edad pediátrica y un problema importante salud pública. Se pretende conocer presentación clínica polisomnográfica SAHS infantil nuestro medio. Estudio descriptivo retrospectivo los estudios realizados a menores 14 años desde 1999 hasta 2012 Unidad Sueño Complejo Hospitalario Universitario Albacete. recogen edad, sexo, datos antropométricos, clínicos, indicación variables estudio sueño, tratamiento evolución....
O determine whether tumor size, categorized as >5 cm or ≤5 cm, influences overall survival in patients with primary breast sarcoma.
El manejo de la vía aérea no difícil es una las habilidades que todo médico debiera dominar. Para ello se requiere el conocimiento conceptos básicos tanto anatómicos como fisiológicos, orientados a mantener un adecuado flujo aire hacia los pulmones. En ciertas ocasiones necesaria utilización algunos dispositivos para este fin, tales cánulas orofaríngeas, mascarilla facial, bolsa ventilar e incluso llegar intubación orotraqueal. Todo será revisado en capítulo. Airway management in non...
La ketamina se ha utilizado en dosis sub-anestésicas pacientes no obesos sugiriendo que su uso disminuye el consumo de morfina postoperatoria, sin embargo, la evidencia literatura es contradictoria. Determinar efecto intraoperatoria durante las primeras 24 horas postoperatorias operados manga gástrica laparoscópica. Ensayo Clínico Controlado, Aleatorizado, doble ciego grupos paralelos unicéntrico realizado entre septiembre del 2015 y Enero 2017. Se incluyeron 18 60 años ambos sexos, con...