A5006587034- Obstructive Sleep Apnea Research
- Neuroscience of respiration and sleep
- Tracheal and airway disorders
- Cardiovascular and Diving-Related Complications
- HIV/AIDS Research and Interventions
- Cardiovascular Disease and Adiposity
- HIV Research and Treatment
- HIV/AIDS drug development and treatment
- Psychosomatic Disorders and Their Treatments
- Peripheral Nerve Disorders
- Ethics and bioethics in healthcare
- Eicosanoids and Hypertension Pharmacology
- Sexual function and dysfunction studies
- Mobile Health and mHealth Applications
- Integrated Circuits and Semiconductor Failure Analysis
- Health Systems, Economic Evaluations, Quality of Life
- Business, Education, Mathematics Research
- Sleep and Wakefulness Research
- Emotion and Mood Recognition
- Neurological Disease Mechanisms and Treatments
- Neurological Complications and Syndromes
- CAR-T cell therapy research
- Sleep and Work-Related Fatigue
- Adolescent Sexual and Reproductive Health
- Cardiac Valve Diseases and Treatments
Hospital Universitari Arnau de Vilanova
2018-2024
Biomedical Research Institute of Lleida
2018-2024
Hackensack University Medical Center
2023
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
2019-2021
Donostia Unibertsitate Ospitalea
2018-2020
Ordem dos Médicos
2002
Rationale: Obstructive sleep apnea (OSA) is associated with increased cardiovascular disease (CVD) risk. Conversely, OSA has not been shown to increase recurrent events in patients acute coronary syndrome (ACS). This lack of homogeneity could suggest that the deleterious effect and its contribution CVD depend on specific patient profiles.Objectives: To evaluate risk for different ACS phenotypes.Methods:Post hoc analysis ISAACC (Continuous Positive Airway Pressure Patients OSA) study,...
Evaluation of microRNAs (miRNAs) could allow characterization the obstructive sleep apnea (OSA) and help diagnose it more accurately. We aimed to examine circulating miRNA profiles establish differences between non-OSA OSA patients. Additionally, we analyse effect continuous positive airway pressure (CPAP) treatment on profile. This observational, longitudinal study included 230 subjects referred Sleep Unit due suspected OSA. Expression profiling 188 miRNAs in plasma was performed 27 by...
Objective To assess the effectiveness and cost-effectiveness of primary care (PC) sleep unit (SU) models for management subjects with suspected obstructive apnoea (OSA). Methods Multicentre, open-label, two-arm, parallel-group, non-inferiority randomised controlled trial. A total 302 OSA and/or resistant hypertension were consecutively enrolled, 149 treated at 11 PC units 153 patients a SU. The outcomes 6-month change in Epworth Sleepiness Scale (ESS) score Health Utilities Index (HUI)....
Objectives Obstructive sleep apnea (OSA) is among the least studied risk factors for erectile dysfunction (ED). We aimed to determine ED prevalence in newly-diagnosed OSA patients, describe their main characteristics and assess continuous positive airway pressure (CPAP) effects on ED. Methods Cross-sectional study assessing patients open-label, parallel, prospective randomized controlled trial evaluating 3-month CPAP treatment sexual function, satisfaction, psychological, hormonal...
Background Continuous positive airway pressure (CPAP) is an effective treatment for obstructive sleep apnea (OSA), but compliance often unsatisfactory. Objective The aim of this study was to assess the effectiveness and cost-effectiveness intelligent monitoring system improving CPAP compliance. Methods This a prospective, open label, parallel, randomized controlled trial including 60 newly diagnosed patients with OSA requiring (Apnea–Hypopnea Index [AHI] >15) from Lleida, Spain....
Rationale: Obstructive sleep apnea (OSA) is prevalent in patients with acute coronary syndrome (ACS) and a cause of secondary hypertension. Objectives: To explore the long-term effects OSA continuous positive airway pressure (CPAP) treatment on blood (BP) ACS. Methods: Post hoc analysis ISAACC study (Continuous Positive Airway Pressure Patients Acute Coronary Syndrome Sleep Apnea; NCT01335087) included 1,803 admitted for (apnea–hypopnea index [AHI], ⩾15 events/h) were randomly assigned to...
Improved antiretroviral treatments and decrease in vertical transmission of HIV have led to a higher number women living with consider childbearing. However, stigma social rejection result specific challenges that positive procreation intentions face with. Our objective was depth analyse elements shaping their desire for specifically investigate the impact HIV. A qualitative study conducted through open interviews 20 between 18 45 years age, from Spanish AIDS Research Network Cohort (CoRIS)....
Obstructive sleep apnea (OSA) is associated with a recurrent cardiovascular event (CVE) risk in patients first acute coronary syndrome (ACS). However, the pathological pathways by which OSA promotes this deleterious role are unknown. We aim to explore proteomic profile that promote CVE severe ACS without previous diseases.This post-hoc analysis from ISAACC study (NCT01335087) included 86 admitted for ACS. Patients underwent respiratory polygraphy 24-72 h diagnosis. analyzed of 276 and...
Background There is a close relationship between obstructive sleep apnoea (OSA) and resistant hypertension (RH). However, studies assessing the long-term effect of diagnosing treating OSA on blood pressure (BP) control in these patients are lacking. Methods To address this gap, we recruited 478 RH from units followed them prospectively after they were screened for through study. By performing 24-h ambulatory BP monitoring (ABPM) annually, management was assessed. Results The had median...
Introduction Obstructive sleep apnea (OSA) severity is based on the apnea-hypopnea index (AHI). The AHI a simplistic measure that inadequate for capturing disease and its consequences in cardiovascular diseases (CVDs). Deleterious effects of OSA have been suggested to influence prognosis specific endotypes patients with acute coronary syndrome (ACS). We aim identify respiratory polygraphy (RP) patterns contribute identifying risk recurrent events ACS. Methods Post hoc analysis ISAACC study,...
<sec> <title>BACKGROUND</title> Continuous positive airway pressure (CPAP) is an effective treatment for obstructive sleep apnea (OSA), but compliance often unsatisfactory. </sec> <title>OBJECTIVE</title> The aim of this study was to assess the effectiveness and cost-effectiveness intelligent monitoring system improving CPAP compliance. <title>METHODS</title> This a prospective, open label, parallel, randomized controlled trial including 60 newly diagnosed patients with OSA requiring...
Abstract Funding Acknowledgements Type of funding sources: Private grant(s) and/or Sponsorship. Main source(s): Instituto de Salud Carlos III (ISCIII) (PI10/02763, PI10/02745, PI18/00449, PI19/00907), co-funded by FEDER “Una manera hacer Europa”, SEPAR, Catalonian Cardiology Society, ResMed Ltd. (Australia), EsteveTeijin (Spain), Oxigen Associació Lleidatana Respiratori (ALLER), CIBERES. MS received financial support from a "Ramón y Cajal" grant (RYC2019-027831-I) the“Ministerio Ciencia e...