- Obstructive Sleep Apnea Research
- Cardiovascular Health and Disease Prevention
- Global Cancer Incidence and Screening
- Neuroscience of respiration and sleep
- Blood Pressure and Hypertension Studies
- Pleural and Pulmonary Diseases
- Child and Adolescent Psychosocial and Emotional Development
- Tracheal and airway disorders
- BRCA gene mutations in cancer
- Cancer Risks and Factors
- Colorectal Cancer Screening and Detection
- Mental Health Treatment and Access
- Cerebrovascular and Carotid Artery Diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Head and Neck Cancer Studies
- Peripheral Artery Disease Management
- Dialysis and Renal Disease Management
- Breast Cancer Treatment Studies
- Vitamin D Research Studies
- Cardiovascular and Diving-Related Complications
- Diabetic Foot Ulcer Assessment and Management
- Cardiovascular Syncope and Autonomic Disorders
- Health disparities and outcomes
- Sleep and related disorders
- Stress and Burnout Research
Biomedical Research Institute of Lleida
2015-2024
Universitat de Lleida
2014-2023
Puigvert Foundation
2018-2021
Hospital Universitari Arnau de Vilanova
2009-2019
Instituto de Salud Carlos III
2016-2018
Centro de Investigación Biomédica en Red de Enfermedades Respiratorias
2011-2018
Universitat Autònoma de Barcelona
2017
Creative Commons
2016
Hospital Arnau de Vilanova
2015
Hospital San Pedro de Alcántara
2013
Objective: To describe the 12‐month and lifetime prevalence rates of mood, anxiety alcohol disorders in six European countries. Method: A representative random sample non‐institutionalized inhabitants from Belgium, France, Germany, Italy, Netherlands Spain aged 18 or older ( n = 21425) were interviewed between January 2001 August 2003. DSM‐IV assessed by lay interviewers using a revised version Composite International Diagnostic Interview (WMH‐CIDI). Results: Fourteen per cent reported...
Continuous positive airway pressure (CPAP) is the first-line treatment for patients with symptomatic obstructive sleep apnea (OSA). However, its indication all sleep-disordered breathing, regardless of daytime symptoms, unclear.To evaluate effect CPAP on incidence hypertension or cardiovascular events in a cohort nonsleepy OSA.Multicenter, parallel-group, randomized controlled trial 14 teaching hospitals Spain. Between May 2004 and 2006, 725 consecutive were enrolled who had an...
Objective: This manuscript examines the impact of mental health state and specific physical disorders on work role disability quality life in six European countries. Method: The ESEMeD study was conducted in: Belgium, France, Germany, Italy, Netherlands Spain. Individuals aged 18 years over who were not institutionalized eligible for an in‐home computer‐assisted interview. Common disorders, loss days (WLD) past month (QoL) assessed, using WMH‐2000 version CIDI, WHODAS‐II, component scores...
Objective: Comprehensive information about access and patterns of use mental health services in Europe is lacking. We present the first results for disorders six European countries as part ESEMeD project. Method: The study was conducted in: Belgium, France, Germany, Italy, Netherlands Spain. Individuals aged 18 years over who were not institutionalized eligible an computer‐assisted interview done at home. 21 425 participants asked to report how frequently they consulted formal due their...
Barbé, Ferran*†; Durán-Cantolla, Joaquín†‡; Sánchez de la Torre, Manuel*†; Martínez-Alonso, Montserrat*; Carmona, Carmen§; Barceló, Antonia†∥; Chiner, Eusebi¶; Masa, Juan F.#†; Gonzalez, Mónica**†††; Marín, Jose M.†††; Garcia-Rio, Francisco‡‡; Atauri, Josefa Diaz**; Terán, Joaquín†§§; Mayos, Mercedes†∥∥; Peña, Mónica†¶; Monasterio, Carmen†¶¶; del Campo, Felix##; Montserrat, Josep M.†*** for the Spanish Sleep and Breathing Network Author Information
Obstructive sleep apnea (OSA) has been associated with increased cancer mortality, but whether it is also incidence unknown.To investigate OSA in a large clinical cohort.A multicenter, cohort study including consecutive patients investigated for suspected between 2003 and 2007 seven Spanish teaching hospitals. Apnea-hypopnea index (AHI) percent nighttime oxygen saturation less than 90% (TSat(90)) were used as surrogates of severity, both continuous variables categorized by tertiles. Cox...
Objective: To assess psychotropic drug utilization in the general population of six European countries, and pattern use individuals with different DSM‐IV diagnoses 12‐month mental disorders. Method: Data were derived from Study Epidemiology Mental Disorders (ESEMeD/MHEDEA 2000), a cross‐sectional psychiatric epidemiological study representative sample 21 425 adults aged 18 or older countries (e.g. Belgium, France, Germany, Italy, Netherlands Spain). Individuals asked about any past 12...
Objective: Comorbidity patterns of 12‐month mood, anxiety and alcohol disorders socio‐demographic factors associated with comorbidity were studied among the general population six European countries. Method: Data derived from Study Epidemiology Mental Disorders (ESEMeD), a cross‐sectional psychiatric epidemiological study in representative sample adults aged 18 years or older Belgium, France, Germany, Italy, Netherlands Spain. The diagnostic instrument used was Composite International...
Objective: The European Study of Epidemiology Mental Disorders (ESEMeD) project was designed to evaluate the prevalence, impact and treatment patterns in Europe. This paper presents an overview methods implemented project. Method: ESEMeD is a cross‐sectional study representative sample 21 425 adults, 18 or older, from general population Belgium, France, Germany, Italy, Netherlands Spain. Composite International Diagnostic Interview (WMH‐CIDI) administered by home interviews January 2001...
Summary The aims of this study areto describe the adequacy treatment for anxiety and depressive disorders in Europe how it differs between providers, using data from ESEMeD overall proportion adequate was 45.8% (57.4% specialised sector 23.3% general medical care sector). Between-country differences were found setting. Organisational political aspects may explain these findings.
The "Pneumonia Zero" project is a nationwide multimodal intervention based on the simultaneous implementation of comprehensive evidence-based bundle measures to prevent ventilator-associated pneumonia in critically ill patients admitted ICU.
Abstract Background Psoriasis is a very prevalent systemic chronic inflammatory disease. Major cardiovascular events are the main cause of mortality in these patients which suggests an association between psoriasis and traditional risk factors. Objective To identify classic factors metabolic syndrome ( MS ) with psoriasis, their possible its severity compare it non‐psoriatic population. Methods This observational cross‐sectional population study Lleida (Spain) from joint hospital/primary...
Medical nutrition therapy based on the control of amount and distribution carbohydrates (CHO) is initial treatment for gestational diabetes mellitus (GDM), but there a need randomized controlled trials comparing different dietary strategies. The purpose this study was to test hypothesis that low-CHO diet GDM would lead lower rate insulin with similar pregnancy outcomes compared diet.A total 152 women were included in open, trial assigned follow either content (40% energy as CHO) or (55%...
The causes of the high cardiovascular mortality observed in chronic kidney disease (CKD) are unknown. Here, we report data on prevalence subclinical atherosclerosis NEFRONA population and a stratified multivariate logistic analysis factors associated with presence plaque. We analysed 2445 patients an estimated glomerular filtration rate (eGFR) <60 mL/min (CKD 3: 937; CKD 4–5: 820; 5D: 688) 559 non-CKD subjects (eGFR >60 mL/min), 18–75 years old, without previous events. An itinerant team...
Loss of 53BP1 rescues BRCA1 deficiency and is associated with BRCA1-deficient triple-negative breast cancers (TNBC) resistance to genotoxic drugs. The mechanisms responsible for decreased transcript protein levels in tumors remain unknown. Here, we demonstrate that loss activates cathepsin L (CTSL)-mediated degradation 53BP1. Activation this pathway rescued homologous recombination repair allowed cells bypass growth arrest. Importantly, depletion or inhibition CTSL vitamin D specific...
To assess quality of life and treatment satisfaction in patients with type 2 diabetes mellitus diabetic retinopathy (DR) using validated instruments, comparison to without DR.A prospective cross-sectional study was designed the influence on who do not have any other advanced late complications that could interfere these outcomes. We included 148 DR 149 DR, all complications. Quality assessed Audit Diabetes Dependent Life (ADDQoL) questionnaire, Treatment Satisfaction Questionnaire (DTSQ)....
Background and objectives Ultrasonographic detection of subclinical atheromatosis is a noninvasive method predicting cardiovascular events. Risk factors progression in CKD are unknown. Predictors were evaluated patients with CKD. Design, setting, participants, & measurements Our multicenter, prospective, observational study included 1553 (2009–2011). Carotid femoral ultrasounds performed at baseline after 24 months. A subgroup 476 was also randomized to undergo ultrasound examination 12...