A5008067254- Orthopedic Surgery and Rehabilitation
- Diabetes Management and Education
- Medical Malpractice and Liability Issues
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Bone fractures and treatments
- Mental Health Treatment and Access
- Gestational Diabetes Research and Management
- Chronic Disease Management Strategies
- Systemic Lupus Erythematosus Research
- Child and Adolescent Psychosocial and Emotional Development
- Obesity and Health Practices
- Health disparities and outcomes
- Mental Health Research Topics
- Coffee research and impacts
- Folate and B Vitamins Research
- Pregnancy and preeclampsia studies
- Pregnancy and Medication Impact
- Healthcare innovation and challenges
- Diabetes Management and Research
- Frailty in Older Adults
- Genomics and Rare Diseases
- Family and Disability Support Research
- Chronic Kidney Disease and Diabetes
- Electrolyte and hormonal disorders
- Down syndrome and intellectual disability research
University of Leicester
2005-2020
NIHR Leicester Biomedical Research Centre
2016
Department of Medical Sciences
2010-2012
University of Leeds
2009-2010
Centre International de Recherche sur le Cancer
2010
University of East Anglia
2010
Glenfield Hospital
2009
University Hospitals of Leicester NHS Trust
2008
Leicester General Hospital
2001-2007
Leicestershire Partnership NHS Trust
2005
Objective: To describe the 12‐month and lifetime prevalence rates of mood, anxiety alcohol disorders in six European countries. Method: A representative random sample non‐institutionalized inhabitants from Belgium, France, Germany, Italy, Netherlands Spain aged 18 or older ( n = 21425) were interviewed between January 2001 August 2003. DSM‐IV assessed by lay interviewers using a revised version Composite International Diagnostic Interview (WMH‐CIDI). Results: Fourteen per cent reported...
Objective: This manuscript examines the impact of mental health state and specific physical disorders on work role disability quality life in six European countries. Method: The ESEMeD study was conducted in: Belgium, France, Germany, Italy, Netherlands Spain. Individuals aged 18 years over who were not institutionalized eligible for an in‐home computer‐assisted interview. Common disorders, loss days (WLD) past month (QoL) assessed, using WMH‐2000 version CIDI, WHODAS‐II, component scores...
Objective: Comprehensive information about access and patterns of use mental health services in Europe is lacking. We present the first results for disorders six European countries as part ESEMeD project. Method: The study was conducted in: Belgium, France, Germany, Italy, Netherlands Spain. Individuals aged 18 years over who were not institutionalized eligible an computer‐assisted interview done at home. 21 425 participants asked to report how frequently they consulted formal due their...
Objective: To assess psychotropic drug utilization in the general population of six European countries, and pattern use individuals with different DSM‐IV diagnoses 12‐month mental disorders. Method: Data were derived from Study Epidemiology Mental Disorders (ESEMeD/MHEDEA 2000), a cross‐sectional psychiatric epidemiological study representative sample 21 425 adults aged 18 or older countries (e.g. Belgium, France, Germany, Italy, Netherlands Spain). Individuals asked about any past 12...
Objective: Comorbidity patterns of 12‐month mood, anxiety and alcohol disorders socio‐demographic factors associated with comorbidity were studied among the general population six European countries. Method: Data derived from Study Epidemiology Mental Disorders (ESEMeD), a cross‐sectional psychiatric epidemiological study in representative sample adults aged 18 years or older Belgium, France, Germany, Italy, Netherlands Spain. The diagnostic instrument used was Composite International...
Objective: The European Study of Epidemiology Mental Disorders (ESEMeD) project was designed to evaluate the prevalence, impact and treatment patterns in Europe. This paper presents an overview methods implemented project. Method: ESEMeD is a cross‐sectional study representative sample 21 425 adults, 18 or older, from general population Belgium, France, Germany, Italy, Netherlands Spain. Composite International Diagnostic Interview (WMH‐CIDI) administered by home interviews January 2001...
Histologic grading systems are used to guide diagnosis, therapy, and audit on an international basis. The reproducibility of is usually tested within small groups pathologists who have previously worked or trained together. This may underestimate the variation scoring systems. We therefore evaluated established system, Banff classification renal allograft pathology, throughout Europe. also sought improve by providing individual feedback after each 14 cases. Kappa values for all features...
Diabet. Med. 27, 887–895 (2010) Abstract Aims Risk assessment scores identify those at high risk of impaired glucose regulation and Type 2 diabetes mellitus. To date no that can be completed by a lay person have been developed validated specifically for multiethnic populations in the UK. Methods We used data on 6186 subjects aged 40–75 years from UK screening study (73% white European, 22% South Asian). All participants were given 75 g oral tolerance test. logistic regression models...
This study explores the epidemiology of patients with a fracture scaphoid presenting to regional teaching hospital.All confirmed over retrospective period between January 2010 and May 2013 were included. Their demographics, deprivation status when occurred was noted assessed. There 415 fractures in 365 males 50 females.The incidence 12.4 100 000 each year general population. The mean age 22 years (nine 35); highest aged 15 19 years. We calculate annual United Kingdom be 7265 year. Patients...
The aim of this study was to describe outcomes in hospitalised older people with different levels frailty and COVID-19 infection.
Background. Comparisons of structured diagnostic interviews with clinical assessments in general population samples show marked discrepancies. In order to validate the CIS-R, a fully interview used for National Survey Psychiatric Morbidity Great Britain, it was compared SCAN, standard, semi-structured, assessment. Methods. A random sample 1882 Leicestershire addresses from Postcode Address File yielded 1157 eligible adults: these 860 completed CIS-R; 387 adults scores [ges ]8 on CIS-R and...
In a retrospective case-note and computer database analysis we assessed the outcome of very elderly patients (> or = 75 years old) with end-stage renal disease (ESRD) on replacement therapy (RRT).Fifty-eight individuals aged over (group 1) commenced RRT between 1 January 1991 31 December 1995. Comparisons were made other commencing who divided into two groups: group 2 (201 65-74 3 (379 <65 old). All subjects followed up until point assessment (30 June 1998), time death, withdrawal from...
Abstract The European Study of the Epidemiology Mental Disorders (ESEMeD/MHEDEA 2000) is a new cross‐sectional study investigating prevalence and associated factors mental disorders, as well their effect on health‐related quality life use services in six countries. This paper describes rationale, methods plan for analysis project. A total 22,000 individuals representative non‐institutionalized population aged 18 over from Belgium, France, Germany, Italy, Netherlands Spain are being...
Plasma coenzyme Q (CoQ) was measured in 20 hyperlipidaemic patients treated with diet and simvastatin (an inhibitor of 3-hydroxy-3-methylglutaryl A (HMG CoA) reductase); 22 alone; normal controls. Patients had a significantly lower plasma CoQ CoQ: cholesterol ratio than either receiving alone or Use inversely independently correlated both (p < 0.0001) 0.01). There significant inverse association between dose 0.001). It is concluded that may the concentration this be greater reduction...
Earlier diagnosis followed by multi-factorial cardiovascular risk intervention may improve outcomes in Type 2 Diabetes Mellitus (T2DM). Latent phase identification through screening requires structured, appropriately targeted population-based approaches. Providers responsible for implementing policy await evidence of clinical and cost effectiveness from randomised trials screen-detected T2DM cases. UK South Asians are at particularly high abnormal glucose tolerance T2DM. To be effective...
To ascertain which factors determine the progression from very low rates of albumin excretion to persistent microalbuminuria in patients with insulin dependent diabetes mellitus.A 10 year prospective study a cohort diabetic patients.Outpatient department Portsmouth District Hospitals.97 mellitus who were initially free and hypertension.Urinary albumin: creatinine ratio.Eight 97 had developed (urinary albumin:creatinine ratio > 3 mg/mmol three consecutive early morning samples) by follow up....
Abstract A cross‐sectional study, based on an epidemiological register, was carried out to describe the prevalence of disabilities, felt needs and use services for adults with learning disability compare outcomes reported morbidity, stress satisfaction among their informal carers. Subjects included 2117 982 carers known specialist in Leicestershire. Behavioural psychological problems epilepsy were main disabilities adults. The leading unmet by residential daycare other forms residence, those...