A5077501735- Dialysis and Renal Disease Management
- Blood Pressure and Hypertension Studies
- Renal Diseases and Glomerulopathies
- Cardiovascular Health and Disease Prevention
- Lipoproteins and Cardiovascular Health
- COVID-19 Clinical Research Studies
- Chronic Kidney Disease and Diabetes
- Central Venous Catheters and Hemodialysis
- Potassium and Related Disorders
- Hormonal Regulation and Hypertension
- Body Composition Measurement Techniques
- Long-Term Effects of COVID-19
- Diabetes, Cardiovascular Risks, and Lipoproteins
- COVID-19 and healthcare impacts
- Muscle and Compartmental Disorders
- Renal and Vascular Pathologies
- Peripheral Artery Disease Management
- Parathyroid Disorders and Treatments
- Hemodynamic Monitoring and Therapy
- Sepsis Diagnosis and Treatment
- Diabetes Treatment and Management
- Intensive Care Unit Cognitive Disorders
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Infective Endocarditis Diagnosis and Management
- Vascular Procedures and Complications
Trinity Health
2023-2024
Hospital General Universitario Gregorio Marañón
2012-2024
Uppsala University
2024
Instituto de Salud Carlos III
2017-2024
Fundación Centro Tecnológico de la Información y la Comunicación
2022
Consejo Superior de Investigaciones Científicas
2022
Biomedical Research Institute of Lleida
2016-2019
Hospital Universitario Severo Ochoa
2018-2019
Ochsner Medical Center
2019
Spanish Clinical Research Network
2019
Hyperuricemia is associated with hypertension, inflammation, renal disease progression, and cardiovascular disease. However, no data are available regarding the effect of allopurinol in patients chronic kidney disease.We conducted a prospective, randomized trial 113 estimated GFR (eGFR) <60 ml/min. Patients were randomly assigned to treatment 100 mg/d (n = 57) or continue usual therapy 56). Clinical, biochemical, inflammatory parameters measured at baseline 6, 12, 24 months treatment. The...
Abstract Background. Patients on kidney replacement therapy comprise a vulnerable population and may be at increased risk of death from coronavirus disease 2019 (COVID-19). Currently, only limited data are available outcomes in this patient population. Methods. We set up the ERACODA (European Renal Association COVID-19 Database) database, which is specifically designed to prospectively collect detailed transplant dialysis patients with COVID-19. For analysis, were included who presented...
Coronavirus disease 2019 (COVID-19) has exposed haemodialysis (HD) patients and kidney transplant (KT) recipients to an unprecedented life-threatening infectious disease, raising concerns about replacement therapy (KRT) strategy during the pandemic. This study investigated association of type KRT with COVID-19 severity, adjusting for differences in individual characteristics.
Background and objectives Ultrasonographic detection of subclinical atheromatosis is a noninvasive method predicting cardiovascular events. Risk factors progression in CKD are unknown. Predictors were evaluated patients with CKD. Design, setting, participants, & measurements Our multicenter, prospective, observational study included 1553 (2009–2011). Carotid femoral ultrasounds performed at baseline after 24 months. A subgroup 476 was also randomized to undergo ultrasound examination 12...
ABSTRACT Background The role of sodium-glucose cotransporter 2 inhibitors (SGLT2i) in the management glomerular/systemic autoimmune diseases with proteinuria real-world clinical settings is unclear. Methods This a retrospective, observational, international cohort study. Adult patients biopsy-proven glomerular were included. main outcome was percentage reduction 24-h from SGLT2i initiation to 3, 6, 9 and 12 months. Secondary outcomes included change estimated filtration rate (eGFR), by type...
Cardiovascular events (CVE) are more prevalent in chronic kidney disease (CKD) than general population, being the main cause of morbimortality. Specific risk factors related to CKD have been suggested, because traditional do not fully explain this increase cardiovascular rates. However, role atheromatosis, its pathogenesis and evolution still unclear. The potential use diagnostic tests detect subclinical atheromatosis has be determined. NEFRONA is a prospective multicenter cohort study. 2445...
Although tacrolimus is recommended by KDIGO Clinical Practice Guideline for Glomerulonephritis the treatment of idiopathic membranous nephropathy (MN), little known about factors that influence response and relapse disease after therapy. Multicentre study collected 122 MN patients with nephrotic syndrome stable renal function treated tacrolimus. Duration was 17.6 ± 7.2 months, including a full-dose tapering period. The percentage remission 60, 78 84% 6, 12 18 months treatment, respectively....
Background: Chronic kidney disease (CKD) is an independent risk factor for atherosclerotic disease. We hypothesized that CKD promotes a proatherogenic lipid profile modifying lipoprotein composition and particle number. Methods: Cross-sectional study in 395 non-diabetic individuals (209 patients 186 controls) without statin therapy. Conventional determinations were combined with advanced profiling by nuclear magnetic resonance, their discrimination ability was assessed machine learning....
El presente artículo estudia la metodología utilizada y resultados obtenidos en el desarrollo de una secuencia cálculo para diseño columnas flotación. estudio se encuentra basado unificación del modelo hidrodinámico química superficie proceso flotación, verificando autenticidad procedimiento mediante comparación sus con experimentales literatura cuatro tipos carbones colombianos (Nechi, Cerrejón, Guachinte La Jagua). Con base realizado, concluyó que sí es posible predecir dimensionamiento...
Background: The ankle-brachial index (ABI) is widely used to diagnose subclinical peripheral artery disease (PAD) in the general population, but data assessing its prevalence and related factors different chronic kidney (CKD) stages are scarce. aim of this study evaluate associated pathological ABI values CKD patients. Methods: NEFRONA a multicentre prospective project that included 2445 patients from 81 centres 559 non-CKD subjects 9 primary care across Spain. A trained team collected...
ABSTRACT Background Proteinuria is not only a biomarker of chronic kidney disease (CKD) but also driver CKD progression. The aim this study was to evaluate serum and urinary tubular biomarkers in patients with biopsied proteinuric correlate them histology outcomes. Methods A single-center retrospective conducted on cohort 156 from January 2016 December 2021. following were analyzed the day biopsy: beta 2 microglobulin (β2-mcg), alpha 1 (α1-mcg), neutrophil gelatinase-associated lipocalin...
Abstract Online hemodiafiltration ( OL‐HDF ) has now demonstrated some benefits in reducing mortality. It seems that rising convective volumes improve the outcomes, but risks of it, such as albumin leakage, are not well defined yet. The aim present study was to evaluate leakage using two different filters with 20 and 30 L post‐dilution . In this cross‐sectional study, prevalent patients receiving OL‐HDL were included. We analyzed dialyzers: FX1000 , FMC Polyflux 210H Gambro. During four...
Objectives . Metformin is the preferred oral antidiabetic agent for type 2 diabetes. Lactic acidosis described as a rare complication, usually during an acute kidney injury (AKI). Material and Methods We conducted prospective observational study of metformin-associated AKI cases four years. 29 were identified. Previous renal function, clinical data, outcomes recorded. Results An episode gastroenteritis precipitated event in 26 cases. Three developed septic shock. patients died, only related...
In chronic kidney disease (CKD) patients on dialysis, plasma interleukin (IL)-6 levels predict mortality better than other markers. Impact of intraindividual changes inflammatory markers cardiovascular (CV) events in CKD is unknown. The aim this study to demonstrate the relation between CV outcomes and variations C-reactive protein (CRP), IL-6, IL-1β, tumor necrosis factor (TNF)-α CKD. Ninety (mean age: 68.5 ± 12.8 years) at different stages (1-4) were evaluated. Serum CRP, TNF-α measured...