1. Transition from compensated left ventricular (LV) hypertrophy to decompensated heart failure was characterized using a pressure-overload induced model elucidate the temporal relationship between cardiomyocyte apoptosis and survival signalling in this transition. 2. Mice were subjected transverse aortic constriction (TAC) or sham operation for 1-16 weeks studied by echocardiography, catheterization histology. Relevant gene expression phosphorylation of extracellular signal-regulated kinase...

Most GPU-based graph systems cannot handle large-scale graphs that do not fit in the GPU memory. The ever-increasing size demands a scale-up system, which can run on single with optimized memory access efficiency and well-controlled data transfer overhead. However, existing either incur redundant transfers or fail to use shared In this paper we present Graphie, systemto efficiently traverse GPU. Graphie stores vertex attribute streams edge asynchronously for processing. Graphie's high...

Pancreatic cancer (PC) is a malignant tumor that seriously threatens the survival of patients. Artificial classification has practical difficulties, such as unstable accuracy, heavy workload, and results depend on subjective judgment clinician during diagnosis staging PC. In addition, accurate PC could better help clinicians deliver optimal therapeutic schedule for patients different stages. Therefore, this study proposes comprehensive medical computer-aided method preoperative based an...

Octamer‑binding transcription factor 4 (OCT4) is one of the factors associated with self‑renewal and differentiation in cancer stem cells, crucial for progression various types human malignancy. However, expression function OCT4 pancreatic has not been fully elucidated. The purpose present study was to investigate molecular mechanisms cells. clinical significance assessed by an immunohistochemical assay using a tissue microarray procedure tissues cells different degrees differentiation. A...

MicroRNAs (miRNAs) act as a kind of small and noncoding RNA, which have been implicated in the regulation various pathobiological processes cancer, including progression pancreatic cancer other human cancers. Previous reports demonstrate that has reported one leading causes cancer-related death, some factors oncogenic genes environments are involved tumorigenesis. In our study, we found microRNA-146a (miR-146a) was evidently downregulated tissues cells. Overexpression miR-146a obviously...

This paper proposes an anomaly-based Intrusion Detection System (IDS), which flags anomalous network traffic with a distance-based classifier. A polynomial approach was designed and applied in this work to extract hidden correlations from related statistics order provide distinguishing features for detection. The proposed IDS evaluated using the well-known KDD Cup 99 data set. Evaluation results show that system achieved better detection rates on set comparison another two state-of-the-art...

Although hypercholesterolemia is a major risk factor for coronary artery disease (CAD), only limited data are available regarding its direct effect on myocardial function apart from CAD. The aim of this study was to evaluate LV systolic using speckle-tracking echocardiography and investigate the relationship between function. Twenty-eight rabbits were randomly divided into three groups: 8 fed normal chow 3 months (group 1) remaining 20 an atherogenic diet 2 2) or 3). Global radial,...

Aiming at solving difficulties related to aero-engine classification and identification, the infrared spectra of hot jets are measured by telemetry Fourier transform spectrometer, a six types jet spectrum data set is generated. The were randomly sampled ratio 8:1:1 generate training set, validation prediction set. In this paper, Peak Finding Siamese Convolutional Neural Network (PF-SCNN) designed match classify data. first place, matching pairs made independently with labels positive...

Human pituitary tumor transforming gene 1 (PTTG1) is an oncogenic transcription factor that overexpressed in many malignancies, especially cancers with metastatic potential, while transgelin-2 (TAGLN2) actin-binding protein shown to be a suppressor. However, the expression and clinical significance of PTTG1 TAGLN2 pancreatic cancer remain unclear. The present study aimed investigate human primary cancer. Seventy-five cases tissues were collected. was assessed using immunohistochemistry (IHC)...

Graph pattern matching searches a data graph for all instances of one or more query patterns. Since it is the most fundamental problems in analytics, many systems have been proposed with distinct features to provide mix flexibility and performance, generally accepted that use cases may necessitate different systems. In this paper, we propose Dryadic, system which integrates comprehensive features, yet can still outperform four state-of-the-art on primary they target. Unlike existing employ...

The aim of this study was to explore the value ultrasonography in screening early stage hepatic alveolar echinococcosis (HAE) animal model, and demonstrate characteristic imaging HAE ultrasonography. experimentally induced secondary 157 rats studied by features all lesions were recorded, compared with pathological results. sensitivity specificity 93.5%, (95% confidence interval: 76%–98%) 83.3% 65%–93%), respectively. typical presented as solid hyperechoic masses mixed lesions. Blood flow...

A novel algorithm is proposed for solving the overlapped marker matching issues and satisfying speed requirement in a 3D video motion capture system. Firstly, mean markers' longitudinal coordination difference two parallel cameras calculated to reduce error. Secondly, epipolar geometry restriction used make corresponding be restricted line. Finally, integrating vertical restriction, searching region of reduced neighborhood one estimated point. Consequently, improved greatly due region. The...

Abstract A trace code pattern location measurement approach is proposed. It includes a method that can precisely extract the to identify color laser printer or photocopier class. In this study, we collected 379 samples from 15 brands, including 129 models and 196 printers photocopiers. The class identified. Four characteristics are used print source: (i) relation between output direction; (ii) observation of shape features among units; (iii) feature arrangement (iv) pattern. Blind testing...

According to the shortages of standard Artificial Fish-school Algorithm (AFSA), this paper improves behaviors fish-school by considering group neighborhood sensing effects, leader mode and Glowworm Swarm Optimization (GSOA). Combining self-adaptive step vision, Gaussian mutation, Genetic (GA), a new AFSA based on mutation operation is raised. By using validation functions test, results show that rate convergence, optimization precision ability avoid precocious phenomenon algorithm are much...

A cohort of 60 breast cancer patients undergoing neoadjuvant chemotherapy (NAC) from January 2021 to December 2022 was studied at the First Affiliated Hospital Xinjiang Medical University.Multimodal ultrasound examinations were conducted before and after NAC.Levels B-lymphocytoma-2 (BCL-2) Ki-67 assessed through immunohistochemistry both NAC during radical mastectomy.Based on Miller-Payne system, efficacy in these categorized into pathologic complete remission (pCR) non-complete (npCR).It...

<h3>Objectives</h3> The aim of this study was to evaluate the changes myocardial strain Rate and Aneurysm volume effect left ventricular aneurysm (LVA) on function in a rabbit model using real time three-dimensional echocardiographic imaging (RT-3DE) combined with two-dimensional speckle-tracking (2D-STI). <h3>Methods</h3> A LVA prepared 30 New Zealand rabbits by ligating middle segment anterior descending artery circumflex (LVA group); 10 control underwent thoracotomy alone. Four weeks...