Physicians have long recognized the association between diabetes mellitus and several pathologic conditions of hand. The most commonly maladies are limited joint mobility (LJM), Dupuytren's disease (DD), trigger finger (TF), carpal tunnel syndrome (CTS). Incidence these hand disorders has increased in setting diabetes. Collectively, described as diabetic syndrome.The aims were to find out prevalence patients, study relation with microvascular complications.This is an observational...

Abstract Background and Objective: Cancer of the cervix is a leading cause morbidity mortality among women worldwide. Therefore, to curb disease, there need develop screening test that has good sensitivity specificity. The present study aimed compare effectiveness Pap smear, visual inspection with acetic acid (VIA) Lugol′s iodine (VILI) for mass premalignant malignant lesions cervix; evaluate usefulness VIA VILI as an adjunct improve cervical cytology; role parallel method enhance its...

The primary objective of this study was to determine the serum level antioxidant enzymes and correlate them with outcome in patients aluminum phosphide (ALP) poisoning and, secondly, evaluate effect N-acetylcysteine (NAC) given along supportive treatment ALP poisoning.We conducted a cohort hospitalized at tertiary care center North India. group control were enrolled during period 1 year from May 2011 April 2012.Oxidative stress evaluated each subject by estimating levels enzymes, viz....

Acute methanol intoxication, which can occur as accidental or suicidal ingestion, is not an unusual poisoning.However, in developing countries adulteration of ethanol a most common cause intoxication.Patients generally present with acute neurological, visual, and gastrointestinal symptoms. 1Brain MRI findings have been characteristic poisoning; bilateral putaminal hemorrhage the finding.Brain seldom done its significance lies when patient remains state altered sensorium even after correction...

Atherosclerosis is related to various cardiovascular and cerebrovascular events like cerebral infarction. Recurrence of ischemic stroke specifically atherosclerotic load as determined by the presence carotid atheromatous plaques its echogenicity.This study was evaluate association recurrence with echogenic characteristics plaque in patients.Carotid sonography using high-resolution 7.5 MHz along gray-scale technique done each patient find occurrence echogenicity according Mannheim Carotid...

Background: Acute febrile encephalopathy (AFE) is a clinical term used to an altered mental state that either accompanies or follows short illness and characterized by diffuse nonspecific brain insult manifested combination of coma, seizures, decerebration. Objective: To identify the etiological diagnosis outcome in adult patients with AFE. Settings Design: A prospective observational study was done aged 14 years above who were admitted AFE at tertiary care center northwest India. Materials...

Organophosphorous (OP) poisoning is one of the most common poisonings seen in India. OP compounds act through inhibition enzyme acetylcholinesterase and estimation pseudocholinesterase (PCE) activity strengthens diagnosis clinically uncertain cases poisoning. The role pralidoxime (PAM) therapy has been controversial.This study was aimed to determine prognostic significance PCE also assess PAM poisoning.Patients suspected age >12 years admitted emergency unit at a tertiary healthcare center...

The clinical presentation of cardiac abnormalities in HIV-infected patients may be atypical or masked by concurrent illnesses that lead to misdiagnosis they remain undiagnosed; therefore, this study was aimed determine the frequency patients.Consecutive age >13 years were studied for 3 months, after obtaining their consent. After assessment, chest x-ray, electrocardiogram, 2-dimensional echocardiography and serum Troponin T levels done.A total 100 studied, cardiomegaly observed x-ray 15%...

The authors report acute hypokalaemic quadriparesis in two young patients that occurred during dengue epidemic 2010 India. Both developed flexic type of pure motor weakness all four limbs without bladder bowel involvement, following 2 to 3 days fever and malaise. Higher mental functions were normal. Serum potassium level was very low; 2–2.5 m mol/l. Non-structural protein (NS₁)-antigen immunoglobulin M-antibody for positive both patients. improved with supplementation. In...

Imatinib mesylate is a tyrosine kinase inhibitor used widely as the first-line treatment for chronic myeloid leukaemia (CML). The side-effect profile of this drug includes fluid retention, muscle cramps, diarrhoea, myelosuppression and skin rashes. Of these, rashes type maculo-papular eruptions oedema developed most commonly. cutaneous adverse reactions other than are rare with imatinib. Severe life-threatening can occur in 5% cases. Here, author reports case newly diagnosed CML that...

Reduction of weight in obese type 2 diabetes mellitus (T2DM) individuals is emerging as a significant strategy the reduction proteinuria diabetic nephropathy along with control hyperglycemia, hypertension, and dyslipidemia. The objective was to evaluate 24-h T2DM patients by loss, conventional therapy (angiotensin-converting enzyme [ACE] inhibitors) arm. A prospective, randomized controlled trial conducted between June 2010 May 2011. confirmed urinary protein estimation body mass index (BMI)...

The authors report a case of dengue fever presenting with aseptic meningoencephalitis and developing subdural haematoma pure motor quadriparesis due to axonal polyneuropathy. This 27-year-old female patient presented us during the latter part epidemic in India 2010. She had mild thrombocytopaenia subtle signs capillary leak. Dengue-specific IgM antibody was positive. initially recurrent seizures. Initial CT scan brain normal cerebrospinal fluid showing albuminocytologic dissociation. After 6...

Rabies is known for most as a fatal infectious disease, mainly transmitted to both humans and animals through bites by rabid animals. In its classical form, rabies well recognised, but when it presents atypically in paralytic may become difficult distinguish from Guillain–Barré syndrome (GBS) or myelitis, particularly where history not forthcoming concealed. The authors report here an atypical case of presenting with descending paralysis followed furious form clue suspicion was MRI findings....

Figure 1 MRI saggital view shows multiple conglomerated ring enhancing lesions (arrow) in pons displaying hypointense core on T1W with perilesional oedema.

An acute poisoning with nitrobenzene presenting as methaemoglobinemia is an uncommon medical emergency. A young girl induced methaemoglobinaemia died despite use of mechanical ventilator, administration oral methylene blue and parenteral ascorbic acid. Here author highlights the rare occurrence such cases, methaemoglobin severe oxidative stress, unexplained splenomegaly leucocytosis ineffectivity other supportive measures in evading death due to poisoning.

Objective: Human immunodeficiency virus (HIV) infection is known to affect every organ system of the body, either directly or through opportunistic infections. Ours was a cross-sectional study determine prevalence thyroid, adrenal, and gonadal dysfunction in HIV patients correlate these with stages infection, antiretroviral therapy, associated wasting. Design: aged ≥15 years were enrolled from July 2009 June 2010. Each patient underwent thorough clinical evaluation, questionnaire specifying...

We describe the images of a 27-year-old man presenting with recurrent syncope due to complete heart block (figure 1). The patient, on further examination, showed ophthalmoplegia, bilateral ptosis 2) and pigmentary retinopathy 3). Kearns-Sayre syndrome (KSS) is rare mitochondrial genetic disorder multisystem involvement. KSS usually presents before age 20 years. triad external opthalmoplegia, retinopathy, cardiac conduction defects are sufficient make confident diagnosis …

Phosgene is a highly toxic gas to which accidental exposure may occur in occupational workers. This case report describes the clinical presentation and management of phosgene poisoning happened after leakage from nearby pipeline. The need suspect observe such patients crucial for life saving, especially view delay deterioration observed some who subsequently develop adult respiratory distress syndrome.

We sought to investigate the incidence and predictors of 30-day mortality associated with ventricular septal rupture (VSR) complicating acute myocardial infarction (AMI) in a cohort patients admitted single centre India.From October 2013 February 2016, total 6560 diagnosis AMI were our institution. Among these patients, those VSR retrospectively included this registry. Clinical echocardiographic features collected all cases. The primary outcome was mortality. A Cox proportional hazard...

Chloroma, also called granulocytic sarcoma or myeloid sarcoma, is a rare malignant extramedullary neoplasm of precursor cells that occurs usually in association with acute leukaemia blast phase chronic (CML). The chloromas are regarded as an early herald systemic relapse, rather than localised process. author reports case multiple skin the CML. patient was treated initially hydroxyurea and disappeared. Patient has been followed for around three half years maintained stable on imatinib therapy.

Nitrobenzene is a nitrite compound often used in polishes or solvents. Its toxic effects are due to its ability induce methaemoglobinaemia. The clinical presentation of this poisoning varies according the concentration methaemoglobin level blood. importance early identification on basis suspicion corroborative with timely intervention required prevent fatal outcome. It also important take care secondary cycling nitrobenzene from body stores recurrence symptoms patients after heavy exposure....

An acute poisoning with nitrobenzene presenting as methaemoglobinemia is an uncommon medical emergency. A young girl induced methaemoglobinaemia died despite use of mechanical ventilator, administration oral methylene blue and parenteral ascorbic acid. Here author highlights the rare occurrence such cases, methaemoglobin severe oxidative stress, unexplained splenomegaly leucocytosis ineffectivity other supportive measures in evading death due to poisoning.

Cysticercosis is the most common parasitic infection of central nervous system. infrequently affects spine, but when it does, can present with symptoms similar to other more spinal diseases. Here, authors report a case disseminated cysticercosis, simultaneous involvement brain and cord. Initially, patient was misdiagnosed as tuberculoma on basis cerebrospinal fluid examination CT scan being treated antitubercular therapy. Later developed quadriparesis which investigated diagnosed be...