José Álvaro Lomelí-Nieto

ORCID: 0000-0002-6620-3017
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About
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Research Areas
  • Systemic Sclerosis and Related Diseases
  • Autoimmune Bullous Skin Diseases
  • Urticaria and Related Conditions
  • Dupuytren's Contracture and Treatments
  • Allergic Rhinitis and Sensitization
  • Connective Tissue Growth Factor Research
  • Animal Virus Infections Studies
  • Bacillus and Francisella bacterial research
  • Kawasaki Disease and Coronary Complications
  • Eosinophilic Disorders and Syndromes
  • Gout, Hyperuricemia, Uric Acid
  • Dermatologic Treatments and Research
  • Mechanical Circulatory Support Devices
  • Inflammasome and immune disorders
  • Rheumatoid Arthritis Research and Therapies
  • Asthma and respiratory diseases
  • Protease and Inhibitor Mechanisms
  • SARS-CoV-2 and COVID-19 Research
  • Hepatitis C virus research

Universidad de Guadalajara
2019-2025

Weatherford College
2022

This is the first study outside of clinical trials (phase I–III) evaluating ability Ad5-nCoV vaccine to generate neutralizing antibodies and factors associated with optimal or suboptimal response. In a longitudinal assay, 346 people (117 prior COVID-19 229 without COVID-19) vaccinated were recruited. The percentage against SARS-CoV-2 (Surrogate Virus Neutralization Test) Ad5 (ADV-Ad5 IgG ELISA) quantified pre post-vaccination effects. induces higher in individuals than those (median [IQR]:...

10.3390/vaccines9091047 article EN cc-by Vaccines 2021-09-20

Abstract Background Metabolic syndrome (MetS) prevalence in rheumatoid arthritis (RA) patients is known to vary considerably across the world. This study aimed determine of MetS RA from western Mexico and analyze interrelation components with clinical variables RA. Methods case‐control included 216 260 control subjects (CS). was determined according NCEP/ATP III Latin American Consensus Diabetes Association (ALAD) criteria. Results observed 30.6% 33.3% controls ( p > 0.05) 28.7% 31.1% for...

10.1002/jcla.23666 article EN cc-by Journal of Clinical Laboratory Analysis 2020-11-24

Systemic sclerosis (SSc) is characterized by a complex interplay of vascular damage, inflammation, and fibrosis, affecting the skin internal organs. Plasminogen activator inhibitor-1 (PAI-1), protein encoded SERPINE1 gene, potential biomarker SSc because it primarily involved in fibrinolysis associated with severity some autoimmune diseases. This study aimed to determine association between variant -675 4G/5G soluble PAI-1 (sPAI-1) levels clinical characteristics risk Mexican population....

10.3390/life14091056 article EN cc-by Life 2024-08-23

Abstract Systemic sclerosis (SSc) is characterized by chronic inflammation and fibrosis, two processes associated with transforming growth factor β (TGF-β) functions. In the present study, we investigated expression of TGF-β isoforms in serum skin distribution receptors (TGF-βR1 TGF-βR2) SSc patients. A total 56 patients 120 control subjects (CS) were included. The levels quantified immunoassay magnetic microspheres, biopsies processed immunohistochemistry (IHC). soluble three active lower...

10.21203/rs.3.rs-1287459/v1 preprint EN cc-by Research Square (Research Square) 2022-02-07
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