A5023689094- Functional Brain Connectivity Studies
- Neural dynamics and brain function
- Advanced Neuroimaging Techniques and Applications
- Advanced MRI Techniques and Applications
- Optical Network Technologies
- Visual perception and processing mechanisms
- Photonic and Optical Devices
- MRI in cancer diagnosis
- Advanced Photonic Communication Systems
- Ophthalmology and Visual Impairment Studies
- Radiomics and Machine Learning in Medical Imaging
- Advanced Fiber Laser Technologies
- Blind Source Separation Techniques
- Medical Imaging Techniques and Applications
- EEG and Brain-Computer Interfaces
- Liver Disease Diagnosis and Treatment
- Endometrial and Cervical Cancer Treatments
- Analytical Chemistry and Chromatography
- Retinal Development and Disorders
- Fetal and Pediatric Neurological Disorders
- Optical Imaging and Spectroscopy Techniques
- Alzheimer's disease research and treatments
- Parkinson's Disease Mechanisms and Treatments
- Hepatitis B Virus Studies
- Central Venous Catheters and Hemodialysis
Hunan Cancer Hospital
2018-2025
Central South University
2018-2025
Imperial College London
2022-2024
Hammersmith Hospital
2023-2024
Shanghai Jiao Tong University
2020-2024
Creative Commons
2023
Imperial College Healthcare NHS Trust
2023
University College London
2023
University College Hospital
2023
Guy's and St Thomas' NHS Foundation Trust
2023
In a group of humans with strabismic amblyopia, the relationship was examined between structure and function different brain regions. Three question were addressed: (1) Is lateral geniculate nucleus (LGN) in amblyopia structurally as well functionally abnormal? (2) Do structural anomalies visual cortex correlate previously reported cortical functional losses? (3) there link any geniculate?The compared by using voxel-based morphometry (VBM) magnetic resonance imaging (fMRI).The results showed...
The understanding of the site and nature cortical processing deficit in human amblyopia awaits resolution three fundamental questions about which there is, at present, much controversy: First, is area V1 affected as present animal models would predict, but some imaging studies argue against? Second, how extensive loss extrastriate function, does it simply follow a consequence an impaired input? Third, brain deficit, be striate or extrastriate, correlate with well-documented psychophysical...
Classical motor symptoms of Parkinson's disease (PD) such as tremor, rigidity, bradykinesia, and axial are graded in the Movement Disorders Society Unified Disease Rating Scale (MDS-UPDRS) III. It is yet to be ascertained whether parkinsonian associated with different anatomical patterns neurodegeneration reflected by brain grey matter (GM) alteration. This study aimed investigate associations between subscores GM at voxel level. High resolution structural MRI T1 scans from Progression...
To predict deep myometrial infiltration (DMI), clinical risk category, histological type, and lymphovascular space invasion (LVSI) in women with endometrial cancer using machine learning classification methods based on image signatures from T2-weighted MR images.A training dataset containing 413 patients an independent testing consisting of 82 cases were employed this retrospective study. Manual segmentation the whole tumor volume sagittal MRI was performed. Clinical radiomic features...
Background and Purpose— Cerebral microbleeds (CMBs) have been observed using magnetic resonance imaging in patients with cardiovascular risk factors, cognitive deterioration, small vessel disease, dementia. They are a well-known consequence of cerebral amyloid angiopathy, chronic hypertension, diffuse axonal injury, among other causes. However, the frequency location new CMBs postadult cardiac surgery, association cognition perioperative yet to be studied. Methods— Pre- postsurgery...
There has been renewed interest in coherent detection to provide high spectral efficiency transmission for short-reach optical interconnects. However, the expensive high-stable laser sources may preclude its potential application. To balance performance and low cost networks, self-coherent homodyne receiver investigated, where dual-polarization (DP) signal remote local oscillator (LO) originating from same source co-propagate over a duplex fiber, enabling remarkable tolerance of linewidth....
Data center interconnects require cost-effective photonic integrated optical transceivers to meet the ever-increasing capacity demands. Compared with a coherent transmission system, complex-valued double-sideband (CV-DSB) direct detection (DD) system can minimize cost of circuit, since it replaces two stable narrow-linewidth lasers only low-cost un-cooled laser in transmitter while maintaining similar spectral efficiency. In carrier-assisted DD carrier power accounts for large proportion...
To delineate the fidelity of functional cortical organization in humans with amblyopia, we undertook an investigation into how spatial information is mapped across visual cortex amblyopic observers. We assessed whether boundaries areas controlled by and fellow fixing eye are same position, retinotopic map within different average receptive field size areas. The was reconstructed using a fMRI phase-encoded mapping analysis. This method sequentially stimulates each point along axes...
Although there is general agreement that the fMRI cortical response reduced in humans with amblyopia, deficit subtle and has little correlation threshold-based psychophysics. From a purely contrast sensitivity perspective, one would expect responses to be selectively for stimuli of low contrasts. However, date, all used studies amblyopia have been high contrast. Furthermore, if selective contrasts, it reflect M-cell loss, because M-cells much higher gain than P-cells make larger contribution...
Abstract Aims and objectives To explore whether the risk of peripheral venous catheters failure remained constant throughout catheter use in adult patients. Background Peripheral catheters, widely used patients, may have a critical threshold dwell time associated with increased failure. Design Prospective, observational study. We complied STROBE checklist items. Methods This study was conducted from July – October 2018 Hunan, China. Data on patient factors, factors events were collected....
The processing deficit in amblyopia is not restricted to just high spatial frequencies but also involves low-medium frequency processing, for suprathreshold stimuli with a broad orientational bandwidth. This the case all three forms of amblyopia; strabismic, anisometropic, and deprivation. Here we use both random block design phase-encoded ascertain (1) extent which fMRI activation reduced at low-mid different visual areas, (2) how accurately mapped across amblyopic cortex. We report loss...
The purpose of this study was to investigate local and network-related changes limbic grey matter in early Parkinson's disease (PD) their inter-relation with non-motor symptom severity. We applied voxel-based morphometric methods 538 T1 MRI images retrieved from the Progression Markers Initiative website. Grey densities cross-sectional estimates age-related change were compared between subjects PD (n = 366) age-matched healthy controls 172) within a regression model, associations density...
Semiparametric survival analysis such as the Cox proportional hazards (CPH) regression model is commonly employed in endometrial cancer (EC) study. Although this method does not need to know baseline hazard function, it cannot estimate event time ratio (ETR) which measures relative increase or decrease time. To ETR, Weibull parametric needs be applied. The objective of study develop and evaluate for EC patients' analysis.
Abstract High‐speed electro‐optic modulators are key components in modern communication networks and various applications that require chip‐scale modulation with large bandwidth, high efficiency, compact footprint. However, fundamental trade‐offs make it challenging to achieve these metrics simultaneously, thus new methodologies must be explored. To this end, a Mach–Zehnder modulator harnessing slow‐light waveguides capacitively loaded slow‐wave electrodes presented on silicon‐nitride‐loaded...
Purpose To determine whether functional connectivity (FC) mapping of nucleus basalis Meynert (NBM) cholinergic network (hereafter, NBM FC) could provide a biomarker central deficits with predictive potential for response to cholinesterase inhibitor (ChEI) treatment. Materials and Methods The Alzheimer's Disease Neuroimaging Initiative (ADNI) was approved by the institutional review boards all participating sites. All participants their representatives gave written informed consent prior data...
Coherent detection is advantageous in achieving high electrical spectral efficiency (ESE) relative to direct (DD), due its capability of field recovery. However, the stringent requirement on laser sources prevents it from being widely utilized cost-sensitive short-reach applications. Carrier-assisted differential (CADD) was proposed retrieve optical without needing for a narrow-linewidth local oscillator (LO) receiver. To realize compact CADD receiver, silicon photonic (SiP) integration...