A5051514246- Scoliosis diagnosis and treatment
- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Pelvic and Acetabular Injuries
- Cervical and Thoracic Myelopathy
- Hip disorders and treatments
- Medical Imaging and Analysis
- Pregnancy-related medical research
- Spondyloarthritis Studies and Treatments
- Spinal Dysraphism and Malformations
- Congenital gastrointestinal and neural anomalies
- Pelvic floor disorders treatments
- Dysphagia Assessment and Management
- Respiratory Support and Mechanisms
- Connective tissue disorders research
- Systemic Sclerosis and Related Diseases
- Renal Diseases and Glomerulopathies
- Medical and Biological Ozone Research
- Social Media in Health Education
- Iron oxide chemistry and applications
- Pregnancy and preeclampsia studies
- Management of metastatic bone disease
- Hippo pathway signaling and YAP/TAZ
- Orthopaedic implants and arthroplasty
- Biomedical Research and Pathophysiology
Nanjing Drum Tower Hospital
2016-2025
Hospital for Special Surgery
2017-2024
Translational Research Institute
2021
Shanghai Sixth People's Hospital
2015-2020
Chinese University of Hong Kong
2019-2020
Nanjing University
2006-2020
Shanghai Jiao Tong University
2015-2019
Cornell University
2017
National Natural Science Foundation of China
2015
Nanjing Children's Hospital
2015
Aims There is a paucity of information on the pre-operative coronal imbalance in patients with degenerative lumbar scoliosis (DLS) and its influence surgical outcomes. Patients Methods A total 284 DLS were recruited into this study, among whom 69 treated surgically remaining 215 conservatively classified based balance distance (CBD): Type A, CBD < 3 cm; B, > cm C7 Plumb Line (C7PL) shifted to concave side curve; C, C7PL convex side. Results 99 (34.8%) patient presented (mean CBD: 48.5,...
Several animal studies have shown an important role for endoplasmic reticulum (ER) stress in AKI, whereas human are lacking. We recently reported that Reticulon-1A (RTN1A) is a key mediator of ER and kidney cell injury. Here, we investigated whether modulation RTN1A expression during AKI contributes to the progression CKD. In retrospective study 51 patients with increased other markers were associated severity injury inducible tubular cell–specific RTN1A-knockdown mouse model subjected folic...
In Brief Study Design. Retrospective case series. Objective. This study reviewed the overall prevalence and indications of revision surgical procedures for adult scoliosis in a single institution. this largest single-institution series, surgery was required relatively low proportion cases (7.61%). The main were implant breakage, deformity progression, infection. Summary Background Data. Spine fusion is considered as final therapeutic intervention management scoliosis. However, reports on...
Study Design. A retrospective study. Objective. To investigate whether the mismatch between proximal junctional angle (PJA) and rod contouring contributed to occurrence of postoperative kyphosis (PJK) in degenerative scoliosis. Summary Background Data. PJK is one complications treatment scoliosis, PI-LL increased stiffness are supposed be etiology PJK. However, impact on has not been fully illustrated. Methods. study was performed 27 consecutive scoliosis patients (three males 24 females)...
To analyze the influence of cervical range motion on preferable sagittal vertical axis in ankylosis spondylitis (AS)-related thoracolumbar kyphosis following single-level pedicle subtraction osteotomy (PSO).
A retrospective radiographical study.To determine the association between disc degeneration and spinal malalignment on both coronal sagittal planes in patients with degenerative lumbar scoliosis (DLS).In recent years, a thorough understanding of balance alignment has become more important treating DLS. Although discs been generally accepted as main cause DLS, to date no study documented relationships curve magnitude well imbalance.In this study, 57 DLS were recruited. Degeneration apical...
Study Design. Retrospective study. Objective. The aim of this study was to propose radiographic characteristics patients with cervical disability and investigate the relevant parameters when assessing alignment. Summary Background Data. Although kyphosis is traditionally recognized as presentation deformity, an increasing number studies demonstrated that may not equal deformity. Therefore, several other differentiating criteria for deformity should be investigated supported quality life...
Retrospective study.To investigate if the surgical outcome of young adults was equivalent to adolescents for correction thoracic adolescent idiopathic scoliosis (AIS).Despite numerous reports on satisfactory correction, some AIS patients or families still have assumption that delay surgery into adulthood may be more beneficial. Hence, strict paired analysis clinical between and adult (AdIS) is required, which lacks report in current literature.This a retrospective 1:1 matched cohort. A total...
In Brief Study Design. A retrospective radiographical study. Objective. To compare compensatory behavior of coronal and sagittal alignment after pedicle subtraction osteotomy (PSO) Smith-Petersen (SPO) for degenerative kyphoscoliosis. Summary Background Data. There was a paucity literature paying attention to the postoperative imbalance PSO or SPO natural evolution imbalance. Methods. study performed on 68 consecutive patients with kyphoscoliosis treated by lumbar (25 patients) (43...
In Brief Study Design. A cross-sectional study. Objective. To identify facet tropism as one of the possible risk factors leading to vertebral rotatory subluxation (VRS). Summary Background Data. VRS has been considered prognostic for degenerative scoliosis. Although several VRS, including age and Cobb angle, have investigated, few studies exist that evaluated correlation between anatomical structures column. Methods. This retrospective study recruited 23 patients diagnosed with lumbar...
Study Design. A retrospective analysis. Objective. To evaluate whether the rotation of presumed lower instrumented vertebra (LIV) on baseline convex side-bending (SB) radiographs leads to distal adding-on in Lenke 5C adolescent idiopathic scoliosis (AIS) patients. Summary Background Data. In 1A patients, derotation LIV bending films is important owing association between and postoperative adding-on. However, relationship patients remains unknown. Methods. Eighty-five with a minimum 2-year...
Background There has been an increasing popularity of searching health related information online in recent years. Despite that considerable amount scoliosis patients have shown interest obtaining through Internet, previous studies demonstrated poor quality information. However, this conclusion may vary depending on region and culture. Since China a restricted Internet access outside its borders, the aim study is to evaluate available using recognized scoring systems analyze as source China....
Study Design: Prospective cohort study. Objectives: Most studies of dysphagia in the cervical spine have focused on a degenerative patient population; rate following surgery for deformity (CD) is unknown. This study aims to investigate if results postoperative dysphagia. Methods: Patients with CD undergoing from 2013 2015 were prospectively enrolled evaluate Demographic, operative, and radiographic variables analyzed. The Quality Life Swallowing Disorders (SWAL-QoL) was used measure Paired t...
Study Design. Cross-cultural adaptation and validation of the Body Image Disturbance Questionnaire-Scoliosis (BIDQ-S). Objective. The aim this study was to validate Chinese version BIDQ-S (C-BIDQ-S) in adolescent idiopathic scoliosis (AIS) patients Mainland China. Summary Background Data. A modified Questionnaire instrument has been validated AIS (BIDQ-S) assess perception spinal appearance psychological disturbance. However, there is no culturally adapted, reliable, for population. Method....
Abstract It is well-documented that melatonin deficiency has been linked to the etiopathogenesis of adolescent idiopathic scoliosis. In this study, we intended apply in melatonin-deficient mice ascertain whether could reduce incidence/severity scoliosis, and investigate role on bone mineral density A total 80 were divided into 4 groups: 20 quadrupedal bipedal served as controls; received oral (8 mg/kg BW) daily. After 5 th , 10 15 weeks treatment, radiographs vivo micro-CT used determine...