A5051307321- Kawasaki Disease and Coronary Complications
- COVID-19 Clinical Research Studies
- Inflammasome and immune disorders
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Impact on Reproduction
- Mechanical Circulatory Support Devices
- Hemostasis and retained surgical items
- Autoimmune and Inflammatory Disorders Research
- Sympathectomy and Hyperhidrosis Treatments
- Occupational Health and Burnout
- Child and Adolescent Health
- Injury Epidemiology and Prevention
- Healthcare professionals’ stress and burnout
- Airway Management and Intubation Techniques
- Foreign Body Medical Cases
- COVID-19 and Mental Health
- Trauma Management and Diagnosis
Hospital Universitário Pedro Ernesto
2020-2023
Universidade do Estado do Rio de Janeiro
2020-2023
To describe the clinical characteristics of children and adolescents admitted to intensive care with confirmed COVID-19.
To describe the clinical, laboratory, and radiological characteristics, as well outcomes of children with MIS-C.
Abstract Background Multisystem Inflammatory Syndrome in Children (MIS-C) is a life-threatening complication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, which manifests as hyper inflammatory process with multiorgan involvement predominantly healthy children the weeks following mild or asymptomatic disease 2019 (COVID-19). However, host monogenic predisposing factors to MIS-C remain elusive. Methods Herein, we used whole exome sequencing (WES) on 16 Brazilian...
To describe the clinical characteristics of children and adolescents admitted to intensive care with confirmed COVID‐19. Prospective, multicenter, observational study, in 19 pediatric units. Patients aged 1 month years consecutively (March–May 2020) were included. Demographic, clinical‐epidemiological features, treatment, outcomes collected. Subgroups compared according comorbidities, age < year, need for invasive mechanical ventilation. A multivariable logistic regression model was used...
Introduction Despite the existing data on Multisystem Inflammatory Syndrome in Children (MIS-C), factors that determine these patients evolution remain elusive. Answers may lie, at least part, genetics. It is currently under investigation MIS-C have an underlying innate error of immunity (IEI), whether monogenic, digenic, or even oligogenic origin. Methods To further investigate this hypothesis, 30 with were submitted to whole exome sequencing. Results Analyses genes associated MIS-C, MIS-A,...
To assess the prevalence of burnout, anxiety and depression symptoms, posttraumatic stress disorder (PTSD) in PICU workers Brazil during first peak COVID-19 pandemic. compare results subgroups stratified by age, gender, professional category, health system, previous mental disorders.
A Síndrome Inflamatória Multissistêmica em Crianças (MIS-C) é uma doença rara e grave, associada ao vírus SARS-CoV-2. As manifestações clínicas são variadas as evidências sobre tratamento farmacológico ainda limitadas, sendo observado o uso de medicamentos anti-inflamatórios imunomoduladores. [Objetivo] Descrever características clínicas, laboratoriais um grupo crianças com MIS-C. [Método] Estudo casos adolescentes MIS-C internadas hospital universitário entre abril dezembro 2020. O...