A5101880533- RNA modifications and cancer
- Plant Molecular Biology Research
- Plant Stress Responses and Tolerance
- HVDC Systems and Fault Protection
- T-cell and B-cell Immunology
- RNA Research and Splicing
- Immune Cell Function and Interaction
- Photosynthetic Processes and Mechanisms
- Cancer-related gene regulation
- Plant Gene Expression Analysis
- Light effects on plants
- Islanding Detection in Power Systems
- Monoclonal and Polyclonal Antibodies Research
- Systemic Lupus Erythematosus Research
- Plant tissue culture and regeneration
- Algal biology and biofuel production
- Turfgrass Adaptation and Management
- Plant nutrient uptake and metabolism
- Genomics and Phylogenetic Studies
- Microscopic Colitis
- Tuberous Sclerosis Complex Research
- Alzheimer's disease research and treatments
- Antioxidant Activity and Oxidative Stress
- Molecular Biology Techniques and Applications
- Corporate Governance and Law
Chonnam National University
2021-2024
Northwest University
2018-2022
Jiangsu Normal University
2016-2020
Sir Run Run Shaw Hospital
2020
Zhejiang University
2020
Wenzhou Central Hospital
2020
Ministry of Education of the People's Republic of China
2018-2019
Beijing Hospital
2007-2018
Shanxi Medical University
2018
Shaanxi Provincial People's Hospital
2018
As the most abundant internal modification of mRNA, N6 -methyladenosine (m6 A) methylation RNA is emerging as a new layer epitranscriptomic gene regulation in cellular processes, including embryo development, flowering-time control, microspore generation and fruit ripening, plants. However, role m6 A plant responses to environmental stimuli remains largely unexplored. In this study, we show that plays an important salt stress tolerance Arabidopsis. All mutants writer components, MTA, MTB,...
Basic region/leucine zipper (bZIP) transcription factors perform as crucial regulators in ABA-mediated stress response plants. Nevertheless, the functions for most bZIP family members tomato remain to be deciphered. Here we examined functional characterization of SlbZIP1 under salt and drought stresses tomato. Silencing resulted reduced expression multiple ABA biosynthesis- signal transduction-related genes transgenic In assays, SlbZIP1-RNAi plants exhibited tolerance compared with WT...
Plants often simultaneously experience combined stresses rather than a single stress, causing more serious damage, but the underlying mechanisms remain unknown. Here, we identified stress-induced IbNAC3 from sweet potato (Ipomoea batatas) as nucleus-localized transcription activator. contains unique activation domain whose MKD sequence confers transactivation activities to multiple other TFs and is essential for activated expression of downstream target genes. Ectopic conferred tolerance...
Abstract N 6 ‐methyladenosine (m A) is an mRNA modification widely found in eukaryotes and plays a crucial role plant development stress responses. FIONA1 (FIO1) recently identified m A methyltransferase that regulates Arabidopsis ( thaliana ) floral transition; however, its response remains unknown. In this study, we demonstrate FIO1‐mediated methylation vital salt Arabidopsis. The loss‐of‐function fio1 mutant was sensitive to stress. Importantly, the complementation lines expressing...
N6-methyladenosine (m6A) is the most abundant internal modification in eukaryotic messenger RNA. Although role of m6A has been demonstrated many biological processes, including embryonic development, flowering time control, microspore generation, fruit ripening, and stress responses, its contribution to other aspects plant development still needs be explored. Herein, we show potential link between deposition expansion tomato (Solanum lycopersicum) fruits through parallel...
Abstract N 6-methyladenosine (m6A) RNA methylation has been shown to play a crucial role in plant development and floral transition. Two recent studies have identified FIONA1 as an m6A methyltransferase that regulates the transition Arabidopsis through influencing stability of CONSTANS (CO), SUPPRESSOR OF OVEREXPRESSION 1 (SOC1), FLOWERING LOCUS C (FLC). In this study, we confirmed is installs marks small group mRNAs. Furthermore, show that, addition its CO, SOC1, FLC, FIONA1-mediated...
Hulless barley (Hordeum vulgare L. var. nudum. hook. f.) has been cultivated as a major crop in the Qinghai-Tibet plateau of China for thousands years. Compared to other cereal crops, Tibetan hulless developed stronger endogenous resistances survive severe environment its habitat. To understand unique resistant mechanisms this plant, detailed genetic studies need be performed. The quantitative real-time reverse transcription-polymerase chain reaction (qRT-PCR) is most commonly used method...
Abstract High salinity is one of the major limiting factors that reduces crop productivity and quality. Herein, we report small SALT TOLERANCE ENHANCER1 (STE1) protein without any known conserved domains required for tomato salt tolerance. Overexpression (OE) SlSTE1 enhanced tolerance to multiple chloride salts (NaCl, KCl, LiCl) oxidative stress, along with elevated antioxidant enzyme activities, increased abscisic acid (ABA) chlorophyll contents, reduced malondialdehyde (MDA) reactive...
NAC (NAM, ATAF, and CUC) transcription factors function as the nodes of regulatory networks in response to various biotic abiotic stresses. Although they have been widely studied many species, no knowledge concerning salt‐stress‐responsive genes is available sweetpotato ( Ipomoea batatas L.). In present study, 12 novel putative genes, designated IbNAC1L IbNAC3 through IbNAC13 , were isolated on basis salt‐stress‐treated RNA sequencing data two cultivars (‘XuShu 22’ ‘XuShu 32’) with different...
Ribosomal RNA (rRNA) methylation is a pivotal process in the assembly and activity of ribosomes, which turn play vital roles growth, development stress responses plants. Although few methyltransferases responsible for rRNA have been identified plant chloroplasts, nature function these enzymes chloroplasts remain largely unknown. In this study, we characterized ArabidopsisRsmD (At3g28460), an ortholog methyltransferase N2-methylguanosine (m2G) modification 16S Escherichia coli. Confocal...
HLA-DQB1*06:02:29 differs from HLA-DQB1*06:02:01:01 by one nucleotide substitution at position 408 (C > T).
Infliximab (IFX) is effective at inducing and maintaining clinical remission mucosal healing in patients with Crohn's disease (CD); however, 9%-40% of do not respond to primary IFX treatment. This study aimed construct validate nomograms predict response CD patients. A total 343 diagnosed who had received induction from four tertiary centers between September 2008 2019 were enrolled this randomly classified into a training cohort (n = 240) validation 103). The outcome was non-response (PNR)...
Identification of a novel human leukocyte antigen-B allele HLA-B*4070.
HLA‐DQB1*03:279 differs from HLA‐DQB1*03:02:01:01 by one nucleotide substitution at position 218 (A>T).