A5040447827- Acute Ischemic Stroke Management
- Peripheral Neuropathies and Disorders
- Parkinson's Disease Mechanisms and Treatments
- Multiple Sclerosis Research Studies
- Cerebrovascular and Carotid Artery Diseases
- Myasthenia Gravis and Thymoma
- Hereditary Neurological Disorders
- Pain Mechanisms and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Botulinum Toxin and Related Neurological Disorders
- Lysosomal Storage Disorders Research
- Cellular transport and secretion
- Neurological disorders and treatments
- Pituitary Gland Disorders and Treatments
- Intracerebral and Subarachnoid Hemorrhage Research
- History of Medical Practice
- Infrared Thermography in Medicine
- Intracranial Aneurysms: Treatment and Complications
- Muscle activation and electromyography studies
- Cerebral Venous Sinus Thrombosis
- Cardiovascular Health and Disease Prevention
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Cardiac electrophysiology and arrhythmias
- Whipple's Disease and Interleukins
- Vagus Nerve Stimulation Research
Metropolitan Hospital
2016-2021
National and Kapodistrian University of Athens
2008-2019
Eginition Hospital
2003-2019
Stroke Association
2019
University of Tennessee Health Science Center
2017
St. Anne's University Hospital Brno
2017
Democritus University of Thrace
2012
University Hospital of Alexandroupolis
2012
University General Hospital Attikon
2008-2010
North Tyneside General Hospital
1999
It is known that essential hypertension may be implicated in the development of cognitive impairment associated to microvascular disease brain. has been hypothesized increased arterial stiffness large arteries lead changes due pulsatile flow. Our study tests hypothesis artery and damage are related brain microcirculation as reflected by impaired function.We studied 110 nondiabetic patients aged 40-80 years (mean age 53.8 +/- 11.2 years, 57 men) with recently diagnosed stage I-II...
Background and purpose Although the first mutation associated with Parkinson's disease ( PD ) was identified several years ago in alpha‐synuclein SNCA gene families of Greek Italian ancestry, a more systematic study this other known mutations has not been performed population. Methods A genetic analysis 111 familial or sporadic early‐onset (≤50 years, EO patients for presence A53T mutation. In separate subgroups these patients, further , LRRK 2, Parkin, PINK 1 DJ ‐1 genes were searched for....
Lysosomal protein 2 (LIMP2), the product of scavenger receptor class B member (SCARB2) gene, is a ubiquitously expressed transmembrane that mannose-6-phosphate-independent for glucocerebrosidase (β-GCase); deficiency in this causes Gaucher disease. Several studies have shown link between mutations β-GCase gene and diseases characterized clinically by Parkinsonism presence Lewy body-related pathology. We hypothesized genetic variants SCARB2 could be risk factors Parkinson's disease (PD). A...
Tumor necrosis factor antagonists (anti-TNFa) are an established therapeutic option for several autoimmune and inflammatory bowel diseases. Despite their clinical effectiveness, neurological adverse events have been reported literature data suggest a potential role of anti-TNFa in the induction demyelination CNS. We present four patients treated with who developed symptoms suggestive CNS demyelination. The first patient, 17-year-old male received etanercept psoriatic arthritis eight months,...
Abstract Autonomic neuropathy, although common in Guillain–Barré syndrome, is considered rare chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and has not been systematically investigated that disorder. The present study was aimed at determining the prevalence of autonomic dysfunction investigating integrity nervous system (ANS) reflexes CIDP. We studied 17 patients with idiopathic CIDP 20 healthy controls. Six quantitative function tests (AFTs) were used: Valsalva ratio,...
<h3>BACKGROUND AND PURPOSE:</h3> Differential diagnosis of multiple system atrophy, progressive supranuclear palsy, and corticobasal degeneration from Parkinson disease on clinical grounds is often difficult. MR imaging biomarkers could assist in a more accurate diagnosis. We examined the utility surface measurements (MR planimetry) differential patients with parkinsonism. <h3>MATERIALS METHODS:</h3> Fifty-two Parkinson-plus (progressive <i>n</i> = 24; degeneration, 9; 19), 18 disease, 15...
The aim of this study was to investigate what extent the existence objective signs diabetic autonomic neuropathy affects corrected QT interval (QTc) in subjects. A total 105 subjects (type 1, n = 53; type 2, 52) as well 40 matched (by age and sex) control were studied. All underwent battery five Ewing tests. Autonomic diagnosed if two tests abnormal. In addition, result each test considered normal (grade 0), borderline 1) or abnormal 2), on basis sum scores we calculated a score for...