Zilong Zhang

ORCID: 0000-0002-7003-6565
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Research Areas
  • Air Quality and Health Impacts
  • Climate Change and Health Impacts
  • Energy and Environment Impacts
  • Air Quality Monitoring and Forecasting
  • Global Health Care Issues
  • Obesity, Physical Activity, Diet
  • Noise Effects and Management
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Birth, Development, and Health
  • Health, Environment, Cognitive Aging
  • Allergic Rhinitis and Sensitization
  • Health disparities and outcomes
  • Parathyroid Disorders and Treatments
  • Physical Activity and Health
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Inflammatory Biomarkers in Disease Prognosis
  • COVID-19 impact on air quality
  • Nutritional Studies and Diet
  • Cardiovascular Health and Risk Factors
  • Blood Pressure and Hypertension Studies
  • Asthma and respiratory diseases
  • Neuroscience of respiration and sleep
  • Traditional Chinese Medicine Analysis
  • Cancer Immunotherapy and Biomarkers
  • Cardiovascular Disease and Adiposity

People's Hospital of Xinjiang Uygur Autonomous Region
2020-2025

Sun Yat-sen University
2021-2024

Yangtze University
2024

Sichuan University
2021-2024

West China Hospital of Sichuan University
2021-2024

Shenzhen University
2017-2024

Shaukat Khanum Memorial Cancer Hospital and Research Center
2024

Combined Military Hospital
2024

Jingzhou Central Hospital
2016-2024

Khyber Teaching Hospital
2024

Understanding the temporal trend of disease burden stroke and its attributable risk factors in China, especially at provincial levels, is important for effective prevention strategies improvement. The aim this analysis from Global Burden Diseases, Injuries, Risk Factors Study (GBD) to investigate national levels China 1990 2019.Following methodology GBD 2019, incidence, prevalence, mortality, disability-adjusted life-years (DALYs) cases Chinese population were estimated by sex, age, year,...

10.1016/s2468-2667(21)00228-0 article EN cc-by-nc-nd The Lancet Public Health 2021-11-25

BackgroundInformation on the effects of long-term exposure to fine particulate matter with an aerodynamic diameter 2·5 μm or less (PM2·5) lung health is scarce. We aimed investigate associations between PM2·5, function, and chronic obstructive pulmonary disease (COPD) in a large-scale longitudinal cohort.MethodsWe included 285 046 participants aged 20 years older from Taiwan MJ Health Management Institution cohort, who were recruited 2001 2014 had spirometric tests during medical examination...

10.1016/s2542-5196(18)30028-7 article EN cc-by The Lancet Planetary Health 2018-03-01

The combined health impact of physical activity (PA) and air pollution on chronic obstructive pulmonary disease (COPD) remains unclear. We investigated the joint effects habitual PA long-term fine particulate matter (PM

10.1186/s12916-022-02274-8 article EN cc-by BMC Medicine 2022-02-28

The associations between air pollution exposure and morbidity mortality of cardiovascular diseases (CVDs) have been widely reported; however, evidence on such across different dynamic disease trajectories remain unknown.

10.1289/ehp10967 article EN Environmental Health Perspectives 2023-01-01

Air pollution has been associated with elevated blood pressure in adults. However, epidemiological evidence from children and adolescents is limited. We investigated the associations between long-term exposure to particulate matter (PM) air a large population of adolescents. A cross-sectional analysis was performed nationally representative sample consisting 43,745 aged 7 18 years seven provinces China. Exposure ambient fine particles (PM2.5) thoracic (PM10) estimated using spatiotemporal...

10.1016/j.envint.2019.04.036 article EN cc-by-nc-nd Environment International 2019-05-03

Background: Long-term exposure to particulate matter (PM) air pollution may increase blood pressure and the risk of hypertension. However, epidemiological evidence is scarce inconsistent. Objectives: We investigated associations between long-term PM with an aerodynamic diameter <2.5μm (PM2.5), pressure, incident hypertension in a large Taiwanese cohort. Methods: studied 361,560 adults ≥18y old from cohort who participated standard medical examination program during 2001 2014. Among this...

10.1289/ehp2466 article EN public-domain Environmental Health Perspectives 2018-01-16

Background: Chronic kidney disease (CKD) is a serious global public health challenge, but there limited information on the connection between air pollution and risk of CKD. Objective: The aim this study was to investigate association long-term exposure particulate matter (PM) with an aerodynamic diameter less than 2.5μm (PM2.5) development CKD in large cohort. Methods: A total 100,629 nonCKD Taiwanese residents age 20 y or above were included 2001 2014. Ambient PM2.5 concentration estimated...

10.1289/ehp3304 article EN public-domain Environmental Health Perspectives 2018-10-01

Metal components in fine particulate matter (PM2.5) from nontailpipe emissions may play an important role underlying the adverse respiratory effects of PM2.5. We investigated associations between long-term exposure to iron (Fe) and copper (Cu) PM2.5 their combined impact on reactive oxygen species (ROS) generation human lungs, incidence asthma, chronic obstructive pulmonary disease (COPD), COPD mortality, pneumonia mortality. conducted a population-based cohort study ∼0.8 million adults...

10.1021/acs.est.0c05931 article EN Environmental Science & Technology 2021-03-05

To characterize the association of ambient particulate matter (PM) pollution different sizes (PM ≤1 µm in aerodynamic diameter [PM1], PM2.5, and PM10) with in-hospital case fatality among patients stroke China.We collected hospitalizations due to 4 provinces China from 2013 2019. Seven-day annual averages PM prior hospitalization were estimated using bilinear interpolation residential addresses. Associations random-effects logistic regression models. Potential reducible fraction number...

10.1212/wnl.0000000000200546 article EN Neurology 2022-05-25

BackgroundCardiovascular disease (CVD) remains a paramount contemporary health challenge. This study examined age-specific effects of 14 risk factors on CVD and mortality in different age groups.MethodsWe analyzed data from 226,759 CVD-free participants aged 40 years older the UK Biobank during period baseline time (2006–2010) to September 30, 2021. The primary outcome was composite incident coronary artery disease, heart failure, stroke. We calculated hazard ratios (HRs)...

10.1016/j.eclinm.2023.102230 article EN cc-by EClinicalMedicine 2023-09-27

Background No prior study has examined the effects of air pollution on progression from healthy to chronic lung disease, subsequent multimorbidity and further death. Methods We used data UK Biobank 265 506 adults free disease at recruitment. Chronic was defined as coexistence least two diseases, including asthma, obstructive pulmonary cancer. The concentrations pollutants were estimated using land-use regression models. Multistate models applied assess effect multimorbidity. Results During a...

10.1136/thorax-2022-219489 article EN Thorax 2023-02-02

Objective To examine the effects of fish oil supplements on clinical course cardiovascular disease, from a healthy state to atrial fibrillation, major adverse events, and subsequently death. Design Prospective cohort study. Setting UK Biobank study, 1 January 2006 31 December 2010, with follow-up March 2021 (median 11.9 years). Participants 415 737 participants, aged 40-69 years, enrolled in Main outcome measures Incident cases death, identified by linkage hospital inpatient records death...

10.1136/bmjmed-2022-000451 article EN cc-by BMJ Medicine 2024-04-01

Biosensing is vital for many areas like disease diagnosis, infectious prevention, and point-of-care monitoring. Microfluidics has been evidenced to be a powerful tool biosensing via integrating biological detection processes into palm-size chip. Based on the chip structure, microfluidics two subdivision types: open closed microfluidics, whose operation methods would diverse. In this review, we summarize fundamentals, liquid control methods, applications of separately, point out bottlenecks,...

10.1016/j.mtbio.2024.101048 article EN cc-by Materials Today Bio 2024-04-04

Particulate matter (PM) air pollution is associated with the risk of cardiovascular morbidity and mortality. However, biological mechanism underlying associations remains unclear. Atherosclerosis, pathology disease, a chronic inflammatory process. We therefore investigated association long-term exposure to fine PM (PM2.5) C-reactive protein (CRP), sensitive marker systemic inflammation, in large Taiwanese population. Participants were from cohort who participated standard medical examination...

10.1093/ije/dyx069 article EN cc-by-nc International Journal of Epidemiology 2017-04-12

Childhood obesity has been a serious public health problem. An effective school-based physical activity (PA) intervention is still lacking in China. This study aimed to assess the effectiveness of during 12 weeks on and related outcomes school children. It was non-randomized controlled trial. Altogether 921 children aged 7 15 years were recruited at baseline survey. Children group (n = 388) participated multi-component that included improvement education, extracurricular activities for...

10.1186/1471-2458-14-1282 article EN cc-by BMC Public Health 2014-12-01

Environmental exposure to chemicals has been considered a potential factor contributing deteriorated semen quality. However, previous literature on air pollution and quality is inconsistent. We therefore investigated the health effects of short-term long-term fine particulate matter (PM2.5) in Taiwanese men from general population.A cross-sectional study was conducted among 6475 male participants aged 15-49 years who participated standard medical examination programme Taiwan between 2001...

10.1136/oemed-2017-104529 article EN cc-by-nc Occupational and Environmental Medicine 2017-11-13

Aims To evaluate the effects of habitual leisure-time physical activity (LTPA) on incident type 2 diabetes in a prospective cohort Chinese adults with impaired fasting glucose (IFG). Methods 44 828 aged 20–80 years newly detected IFG but free from cardiovascular and cerebrovascular disease were recruited followed up 1996 to 2014. Incident was identified by plasma ≥7 mmol/L. The participants classified into four categories based their self-reported weekly LTPA: inactive, low, moderate, or...

10.1136/bjsports-2017-098199 article EN British Journal of Sports Medicine 2018-01-13

Little information is available regarding the effect of sleep on development chronic kidney disease (CKD). This large-cohort study aimed to investigate association between and incidence CKD. We recruited 194,039 participants without CKD aged 20 years or older 1996 2014. Incident was defined as an estimated glomerular filtration rate < 60 mL/min/1.73 m2. Information about duration quality obtained from a questionnaire used generate score reflecting profile. Cox proportional hazards regression...

10.5664/jcsm.7660 article EN Journal of Clinical Sleep Medicine 2019-03-14
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