A5038070558- Birth, Development, and Health
- Obesity, Physical Activity, Diet
- Child Nutrition and Water Access
- Health, Environment, Cognitive Aging
- Nutritional Studies and Diet
- Hydrocarbon exploration and reservoir analysis
- Methane Hydrates and Related Phenomena
- Advanced Combustion Engine Technologies
- Cardiovascular Disease and Adiposity
- Epigenetics and DNA Methylation
- Gestational Diabetes Research and Management
- Climate Change and Health Impacts
- Biodiesel Production and Applications
- Cancer-related gene regulation
- SARS-CoV-2 and COVID-19 Research
- Geological Studies and Exploration
- Diet and metabolism studies
- Human Health and Disease
- Heat transfer and supercritical fluids
- SARS-CoV-2 detection and testing
- Body Composition Measurement Techniques
- Combustion and flame dynamics
- Air Quality and Health Impacts
- Advanced Welding Techniques Analysis
- COVID-19 and Mental Health
Zhengzhou University of Aeronautics
2019-2025
Oil and Gas Center
2024-2025
Ministry of Natural Resources
2024-2025
China Geological Survey
2024-2025
Case Western Reserve University
2013-2025
Southern Medical University
2020-2023
Peking University
2015-2021
King University
2015-2019
Stanford University
2017
Hunan University
2016
Risk for transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to close contacts infected persons has not been well estimated.
Abstract Background Rapid spread of SARS-CoV-2 in Wuhan prompted heightened surveillance Guangzhou and elsewhere China. Modes contact risk transmission among close contacts have not been well estimated. Methods We included 4950 closes from Guangzhou, extracted data including modes contact, laboratory testing, clinical characteristics confirmed cases source cases. used logistic regression analysis to explore the factors associated with infection contacts. Results Among contacts, median age...
CHD7 is a member of the chromodomain helicase DNA binding domain family ATP-dependent chromatin remodeling enzymes. De novo mutation gene major cause CHARGE syndrome, genetic disease characterized by complex constellation birth defects ( C oloboma eye, H eart defects, A tresia choanae, severe R etardation growth and development, G enital abnormalities, E ar abnormalities). To gain insight into function CHD7, we mapped distribution protein on using approach immunoprecipitation tiled...
Abstract Although most colorectal cancers are chromosomally unstable, the basis for this instability has not been defined. To determine whether genes shown to cause chromosomal in model systems were mutated cancers, we identified their human homologues and determined sequence a panel of cancers. We found 19 somatic mutations five representing three distinct pathways. Seven MRE11, whose product is involved double-strand break repair. Four among hZw10, hZwilch/FLJ10036, hRod/KNTC, products...
Air pollution has been associated with elevated blood pressure in adults. However, epidemiological evidence from children and adolescents is limited. We investigated the associations between long-term exposure to particulate matter (PM) air a large population of adolescents. A cross-sectional analysis was performed nationally representative sample consisting 43,745 aged 7 18 years seven provinces China. Exposure ambient fine particles (PM2.5) thoracic (PM10) estimated using spatiotemporal...
We sought to develop and validate a national blood pressure (BP) reference based on age, sex, height for Chinese children. Data were obtained 197 430 children aged 7 17 who participated in the National Survey Students’ Constitution Health 2010. BP percentiles estimated fitted using lambda, mu, sigma method then compared with US China existing reference. In an external independent validation sample of 59 653 18 from provinces 2013, prevalence elevated was applying 3 references. values similar...
Kaposi's sarcoma (KS) is a disease of multifocal vascular proliferation that requires infection with KS herpes virus (KSHV/HHV-8). Activation the c-kit and platelet-derived growth factor (PDGF) receptors by autocrine/paracrine mechanisms follows endothelial cell KSHV infection. In pilot study, imatinib, c-kit/PDGF-receptor inhibitor, induced partial regression AIDS-associated (AIDS-KS) in five 10 patients.This multicenter phase II study was designed to estimate response rate imatinib...
To evaluate the association of early-life exposure to Chinese Great Famine (1959–1961) with DNA methylation in IGF2 and its subsequent influence on blood lipid levels late adulthood among participants Genomic Research (GRECF) study. The GRECF study recruited 790 born between 1956 1964 from 2 neighbor provinces, Anhui Jiangxi, China through a multistage, clustered, random sampling. current included sample 188 participants. differential region (DMR) is an intragenic DMR located upstream...
Background & aimsThe association between dietary diversity (DD) changes and mortality remains unclear. We aimed to investigate the DD all-cause among older people.MethodsA total of 17,959 participants with a mean age 84.8 years old were enrolled at baseline. Food groups collected baseline follow-up using simplified food frequency questionnaire (FFQ), then overall, plant-based animal-based score (DDS) calculated. DDS calculated first follow-up. The three (overall, DDS) subsequent evaluated....
Early-life developmental adaptations in response to severe malnutrition may play a crucial role susceptibility hypertension. This study aimed explore the associations between exposure Chinese famine (1959-1961) at fetal, infant and preschool stages during fetal life or childhood risk of hypertension adulthood.We used data 1,966 adults born 1956 1964 selected families from China Health Retirement Longitudinal Study (CHARLS) national survey.Prevalence among non-exposed, fetal-exposed,...
The urban-rural disparity for childhood overweight and obesity shows different patterns in most countries. This study aimed to examine the recent trend of at national subnational levels Chinese children from 2010 2014.Two successive cross-sectional studies. Overweight were classified using age-specific sex-specific body mass index reference. prevalence was compared between urban rural areas levels.Thirty-one provinces China.Data obtained National Survey on Students' Constitution Health 2014...
There was growing interest in endocrine disrupting chemicals that might have effect on the obesity epidemic, but few studies association of phthalates (PAEs) with childhood overweight and China based longitudinal cohort study were available, which purpose present study. A nested case-control conducted a prospective 2298 children aged 7–13 years from October 2017 to 2020 five waves visits Xiamen city, China. total 829 remained first wave follow up collection urine for measuring seven PAEs...
Based on the Johnson–Cook constitutive model and modified Coulomb's law, study investigates impact of various process parameters weld temperature field in high-strength 5052 aluminum alloy friction stir welding (FSW) for aerospace applications. Utilizing a thermo-mechanical model, significance rotational speed, indentation peak is examined through Taguchi's orthogonal experimental design. S/N ratio ANOVA results show that speed has most significant effect weld, followed by amount...
ABSTRACT In Sichuan Basin, uranium (U) and thorium (Th) are more abundant in organic‐rich shale than granitic rocks, suggesting that is a significant source rock for helium (He). However, the He generation potential of enrichment mechanisms gas fields remain limited understanding. Based on He, U Th concentration tests, fluid inclusion analysis Jiaoshiba field, it was found concentrations 340–730 ppm. The helium‐rich (≥ 500 ppm) primarily synclinal units. biggest abundance area (0.27 m 3 /m 2...
Colorectal cancer is the second leading cause of death in United States. The adenomatous polyposis coli (APC) pathway plays a critical role colorectal tumorigenesis, but mechanism not fully understood. In this issue JCI, Luo and colleagues used genetically engineered mouse models to show that high mobility group A (HMGA1) mediator development colon tumors driven by loss Apc gene. HMGA1 activated transcription Achaete-Scute Family BHLH Transcription Factor 2 (ASCL2), which regulated...
To explore the associations between Chinese famine exposure in early life and dyslipidemia adulthood.We selected 2752 participants from baseline survey of China Health Retirement Longitudinal Study (CHARLS) 2011-2012 to evaluate with risk adulthood. Dyslipidemia was defined as TC (Total Cholesterol): HDL-C (High-Density Lipoprotein Cholesterol) ratio ≥ 5.0 or use cholesterol lowering drugs. Famine cohorts were categorized by birthdates participants. Binary logistics regression model used...
Abstract Background Next-generation sequencing technologies generate a significant number of short reads that are utilized to address variety biological questions. However, quite often, tend have low quality at the 3’ end and generated from repetitive regions genome. It is unclear how different alignment programs perform under these cases. In order investigate this question, we use both real data simulated with above issues evaluate performance four commonly used algorithms: SOAP2, Bowtie,...
The association between vegetable intake and blood pressure (BP) in adolescents is still inconsistent, the description of recommended daily consumption abstract nonfigurative. Here we aimed to investigate BP further look for a simple way describe satisfactory level adolescents. We recruited 18,757 adolescents, aged 13–17 years, from seven provinces China 2013. A standard physical examination, including height, weight was conducted. Information regarding collected by questionnaire, one...
We aimed to assess the associations between adiposity distribution and cardiometabolic risk factors among overweight obese adults in China, demonstrate sex differences these associations.A total of 1221 participants (455 males 766 females) were included this study. Percentage body fat (PBF) whole regional areas, including arm, thigh, trunk, android, gynoid, measured by dual-energy X-ray absorptiometry method. Central was waist circumference. Clustered defined as presence two or more six...