- Fatty Acid Research and Health
- Cancer, Lipids, and Metabolism
- Biopolymer Synthesis and Applications
- Nutrition, Genetics, and Disease
- Lung Cancer Treatments and Mutations
- Phytoestrogen effects and research
- COVID-19 epidemiological studies
- Colorectal Cancer Treatments and Studies
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Digestive system and related health
- Helicobacter pylori-related gastroenterology studies
- Blood Pressure and Hypertension Studies
- Cancer Research and Treatments
- Healthcare Systems and Reforms
- Liver Disease Diagnosis and Treatment
- Dementia and Cognitive Impairment Research
- Health Systems, Economic Evaluations, Quality of Life
- COVID-19 and healthcare impacts
- Complementary and Alternative Medicine Studies
- Biological Research and Disease Studies
- Global Health and Surgery
- Global Maternal and Child Health
- Smoking Behavior and Cessation
- Lung Cancer Research Studies
Chinese Academy of Sciences
2021-2025
Shenzhen Technology University
2024-2025
Shenzhen University
2024-2025
Shenzhen Institutes of Advanced Technology
2021-2025
Central South University
2025
Yunnan University of Traditional Chinese Medicine
2025
Guangdong University of Technology
2025
Harbin University
2025
Hunan University of Traditional Chinese Medicine
2025
Chinese University of Hong Kong
2015-2024
Risk for transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) to close contacts infected persons has not been well estimated.
Abstract Background Rapid spread of SARS-CoV-2 in Wuhan prompted heightened surveillance Guangzhou and elsewhere China. Modes contact risk transmission among close contacts have not been well estimated. Methods We included 4950 closes from Guangzhou, extracted data including modes contact, laboratory testing, clinical characteristics confirmed cases source cases. used logistic regression analysis to explore the factors associated with infection contacts. Results Among contacts, median age...
Abstract The high incidence of lung cancer among Chinese females, despite a low smoking prevalence, remains poorly explained. Cooking fume exposure during frying could be an important risk factor. We carried out population-based case-control study in Hong Kong. Cases were female nonsmokers with newly diagnosed primary cancer. Controls randomly sampled from the community, frequency matched by age groups. Face-to-face interviews conducted using standardized questionnaire. “total cooking...
Background— Emerging studies suggest that early administration of dual antiplatelet therapy may be better than monotherapy for prevention recurrent stroke and cardiovascular outcomes in acute ischemic transient attack (TIA). We performed a meta-analysis randomized, controlled trials evaluating versus mono noncardioembolic or TIA. Methods Results— assessed investigating published up to November 2012 the CHANCE trial (Clopidogrel High-risk patients with Acute Non-disabling Cerebrovascular...
BackgroundConstipation is generally considered a common physical symptom of depression or side effect antidepressant treatments. However, according to the gut-brain axis hypothesis, association between and constipation might be bi-directional. This study investigated premorbid depression.MethodsWe conducted retrospective cohort using data from UK Biobank. Individuals free 2006 2010 were included. Constipation status was determined diagnostic codes electronic health records baseline...
Accumulating evidence suggested that long-term antibiotic use may alter the gut microbiome, which has, in turn, been linked to type 2 diabetes. We undertook this study investigate whether was associated with increased risk of
<h3>Background and Objectives</h3> Use of OTC laxatives is common in the general population. The microbiome-gut-brain axis hypothesis suggests use associated with dementia. We aimed to examine association between regular incidence dementia UK Biobank participants. <h3>Methods</h3> This prospective cohort study was based on participants aged 40 69 years without history Regular defined as self-reported most days week for last 4 weeks at baseline (2006-2010). outcomes were all-cause dementia,...
Background The potential modifiable factors influencing irritable bowel syndrome (IBS) have not been thoroughly documented. We aimed to systematically investigate the associated with IBS, while accounting for impact of unobserved confounders and coexisting disorders. Methods Genetic correlation Mendelian randomisation (MR) analyses were integrated identify disorders linked IBS. Subsequently, multiresponse MR (MR 2 ) was employed further examine these associations. Summary-level genome-wide...
Previous studies predominantly focused on single types of congenital birth defects (CBDs) or specific national prevalence. This study adopts a holistic perspective to assess current trends and health inequalities in incidence rate various CBDs, providing novel insights inform public policy formulation. Global, socio-demographic index (SDI) regional, country-specific estimates cases at CBDs from 1990 2021 were derived the Global Burden Disease (GBD) 2021. Joinpoint analysis autoregressive...
Neuroinflammation and neurogenic disorders lead to depression in stroke patients. As, exercise intervention, a non-drug therapy, has been proven effective post-stroke (PSD) However, the underlying molecular mechanism by which improves PSD still needs be explored. Therefore, utilizing mice model, this study aimed observe pathological changes investigate symptoms. A middle cerebral artery occlusion (MCAO)+chronic unpredictable mild stress (CUMS) method was used establish model were subjected...
Trial eligibility criteria, which define an appropriate evaluable population through inclusion and exclusion are fundamental for reliable evidence should be tailored to the question that trial sets out answer [1]. However, criteria cancer trials have become increasingly restrictive over years, with median number increased from 21 in 1986 46 2016 [2, 3]. These created substantial barriers patient access novel therapies, hindered recruitment limited generalizability of results, presenting not...