A5074015080- Pancreatic and Hepatic Oncology Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver Disease Diagnosis and Treatment
- Neuroendocrine Tumor Research Advances
- Liver Disease and Transplantation
- Estrogen and related hormone effects
- Gallbladder and Bile Duct Disorders
- Pancreatitis Pathology and Treatment
- Organ Transplantation Techniques and Outcomes
- Nutrition and Health in Aging
- Gastric Cancer Management and Outcomes
- Augmented Reality Applications
- Inflammatory Biomarkers in Disease Prognosis
- Cancer, Lipids, and Metabolism
- Renal Transplantation Outcomes and Treatments
- Renal cell carcinoma treatment
- Cancer Treatment and Pharmacology
- Surgical Simulation and Training
- Esophageal and GI Pathology
- Hepatitis C virus research
- Cancer Genomics and Diagnostics
- Lung Cancer Treatments and Mutations
- Venous Thromboembolism Diagnosis and Management
- Lung Cancer Research Studies
The Jikei University Hospital
2016-2025
Jikei University School of Medicine
2015-2024
Japanese Foundation For Cancer Research
2017
Greater Poland Cancer Center
2017
North Medical Center
2017
Tokyo University of Technology
2016
Tokyo Women's Medical University
2016
International University of Health and Welfare
2015
Osaka City General Hospital
2000
The prognosis of biliary tract cancer is extremely poor, with a 5-year survival rate 20%. Surgery the only treatment that can be expected to cure cancer, but because many cases are unresectable or recurrent, chemotherapy has become standard treatment. effects first-line administration durvalumab have not been explored. This study examined whether an additive effect in first line. Twenty-three patients who were diagnosed recurrent non-resected requiring anticancer recruited. Three these...
Biliary intraepithelial neoplasia (BilIN) is defined as a bile duct epithelial tumor with intraductal papillary of the duct. BiIlN precancerous lesion intrabiliary neoplasia. We performed laparoscopic hepatic resection for recurrent cholangitis due to intrahepatic lithiasis and diagnosed BilIN. This case suggests that it necessary consider possibility malignancy in cases repeat lithiasis. A 34-year-old man developed cholecystitis gallstones at age 25 years underwent cholecystectomy 26 years....
We investigated the prognostic impact of osteosarcopenia, which is combination osteopenia and sarcopenia, in patients with colorectal liver metastases (CRLM) after hepatic resection.
<b><i>Aim:</i></b> The aim of this study was to evaluate the utility navigation surgery using augmented reality technology (AR-based NS) for pancreatectomy. <b><i>Methods:</i></b> 3D reconstructed images from CT were created by segmentation. initial registration performed optical location sensor. superimposed onto real organs in monitor display. Of 19 patients who had undergone hepatobiliary and pancreatic AR-based NS, accuracy, visualization...
Frailty, represented by sarcopenia and osteopenia, has been associated with worse survival after hepatectomy in patients hepatocellular carcinoma. Recently, the concept term "osteosarcopenia" have proposed, which outcome several malignancies.This study included 227 who underwent elective hepatic resection for Osteopenia was evaluated computed tomographic measurement of pixel density midvertebral core 11th thoracic vertebra. The skeletal muscle index (SMI) psoas areas at third lumbar...
We previously developed an image-guided navigation system (IG-NS) using augmented reality technology for hepatobiliary and pancreatic (HBP) surgery. This superimposed a 3D model onto stereoscope-captured surgical field (i.e., the scope method). Unfortunately, this method requires expensive stereoscope, surgeons have to shift their eyesight away from field, has poor controllability. Therefore, IG-NS tablet PC method) was developed. The aim of current study is evaluate efficiency novel...
Abstract Aim This study sought to evaluate the incidence, risk factors, and clinical outcomes of portal vein thrombosis after hepatectomy. Furthermore, we proposed a novel classification treatment strategy for Methods We retrospectively analyzed 398 patients who underwent hepatectomy enhanced computed tomography imaging within 14 days surgery in our hospital from 2009 2019. Portal was classified into three categories according location thrombus – main, hilar, peripheral with main further...
Background To achieve safety of the operation, preoperative simulation became a routine practice for hepatobiliary and pancreatic (HBP) surgery. The use intraoperative ultrasonography (IOUS) is essential in HBP There limitation IOUS laparoscopic surgery (LS), which new system expected. We have developed an image‐guided navigation (IG‐NS) open since 2006, we applied our to LS. aim this study evaluate results clinical application IG‐NS Materials methods Eight patients underwent LS using IG‐NS;...
To study exocrine function of the remnant pancreas after pancreatoduodenectomy (PD), we propose use an index (PEI) that combines volume and intraoperative amylase activity pancreatic juice. Here, aimed to determine whether PEI can predict non-alcoholic fatty liver disease (NAFLD) following PD. Fifty-seven patients for whom juice was measured during PD were enrolled. NAFLD defined as a liver-to-spleen attenuation ratio <0.9 on plain CT 1 year surgery. We retrospectively evaluated clinical...
To evaluate omega-3 fatty acid-rich enteral nutrient effects in patients with unresectable or recurrent biliary tract pancreatic cancers during chemotherapy. Enteric nutritional supplements containing acids (Racol®) was administered to aforementioned The skeletal muscle mass and blood test data were obtained pre-administration 28 56 days after. Patients cancer the digestive enzyme supplement pancrelipase (LipaCreon®) after start of Racol® administration. number chemotherapies skipped due...
The aim of this study was to investigate the risk factors surgical site infection (SSI) in patients who underwent liver resection for colorectal metastases (CRLM).A total 151 CRLM were included study. We investigated relationship between patient characteristics and perioperative incidence SSI.Nineteen (13%) these developed SSI. Multivariate analysis revealed that modified Glasgow Prognostic Score (mGPS) (1 or 2, odds ratio 3.86, p=0.03) presence an enterostomy (yes, 3.93, p=0.04) significant...
Undifferentiated carcinoma with osteoclast-like giant cells (UCOGCs) is a rare subtype of pancreatic cancer (PC), and its clinicopathological characteristics are still unclear. Herein, we report case initially unresectable UCOGC that was successfully resected after FOLFIRINOX therapy.A 63-year-old man referred to us for evaluation mass detected by computed tomography (CT) during medical checkup. Computed showed 7.5-cm tumor located in the head body, which involved common hepatic artery...
To assess the efficacy of combination chemotherapy with nafamostat mesilate, gemcitabine and S-1 for unresectable pancreatic cancer patients.The study was conducted as a single-arm, single center, institutional review board-approved phase II trial. Patients received nafamosntat mesilate (4.8 mg/kg continuous transregional arterial infusion) (1000 mg/m2 transvenous) on days 1 and15, oral [(80 mg/day (BSA<1.25 m2), 100 (1.25 ≤ BSA<1.5 or 120 (BSA ≥1.5 m2)] 1-14 or, 1-7 15-21. This regimen...
Background/Aim: After primary resection of hepatocellular carcinoma (HCC), the impact patient9s characteristics at initial hepatectomy, on long-term remnant liver function has not been reported. The aim this study was to identify factors associated with deterioration among patients who developed recurrent HCC. Patients and Methods: A total 51 intrahepatic recurrence after hepatic for HCC were included. We retrospectively investigated relation between patient degree upon recurrence. Results:...
Intrahepatic portal and hepatic venous shunts have been reported in children (Takama et al. Surg Case Rep 2020;6(1):73) but are very rare adults (Papamichail Hepatobiliary Pancreat Dis Int 2016;15(3):329-333). Treatment is indicated cases of hypertension or hyperammonemia. We evaluated the usefulness, safety, effectiveness laparoscopic liver resection for this case. After performing intraoperative ultrasonography, hilar plate was manipulated to identify target Glissonean branch segment 5...