A5030739920- Bone and Dental Protein Studies
- Connective Tissue Growth Factor Research
- Periodontal Regeneration and Treatments
- dental development and anomalies
- Endodontics and Root Canal Treatments
- Dental materials and restorations
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Oral and Maxillofacial Pathology
- Asthma and respiratory diseases
- Infectious Diseases and Tuberculosis
- Graphene and Nanomaterials Applications
- Blood Coagulation and Thrombosis Mechanisms
- Bone Tissue Engineering Materials
- Infective Endocarditis Diagnosis and Management
- Oral microbiology and periodontitis research
- Protease and Inhibitor Mechanisms
- Allergic Rhinitis and Sensitization
- 3D Printing in Biomedical Research
- Vitamin K Research Studies
- Otolaryngology and Infectious Diseases
- TGF-β signaling in diseases
- Glycosylation and Glycoproteins Research
- Pediatric health and respiratory diseases
- Additive Manufacturing and 3D Printing Technologies
Kanagawa Dental University
2015-2024
Nihon University
2011-2015
Abstract Matrix metalloproteinase‐3 (MMP‐3) expression is promoted after pulpotomy, and application of MMP‐3 to dental pulp pulpotomy accelerates angiogenesis hard tissue formation. However, the mechanism by which promotes wound healing still unclear. Connective growth factor/CCN family 2 (CTGF/CCN2), a protein belonging CCN family, considered participate in healing, angiogenesis, cell migration. In this study, we examined involvement CTGF/CCN2 MMP‐3‐induced migration human (fibroblast‐like)...
Purpose We considered the possibility of reducing industrial waste by fabricating and reusing dental models prepared using a fused deposition modeling (FDM) 3D printer polylactic acid (PLA) filaments. The purpose this study was to verify accuracy fabricated FDM PLA.
Connective tissue growth factor/CCN family 2 (CTGF/CCN2) has been considered to participate in tooth development. To date, the expression and role of CTGF/CCN2 reparative dentinogenesis have unclear. Our previous study revealed that matrix metalloproteinase-3 (MMP-3) stimulates cell migration via secretion human dental pulp cells, this is dependent on dynamin-related endocytosis independent protease activity. The objective present was determine dentin carious teeth examine effect...
Plasma kallikrein (KLKB1), a serine protease, cleaves high-molecular weight kininogen to produce bradykinin, potent vasodilator and pro-inflammatory peptide. In addition, KLKB1 activates plasminogen other leukocyte blood coagulation factors processes pro-enkephalin, prorenin, C3. has also been shown cleave protease-activated receptors in vascular smooth muscle cells regulate the expression of epidermal growth factor receptor. this study, we investigated KLKB1-dependent inflammation...
Objective CCN family member 2/connective tissue growth factor ( 2/ CTGF ) is known as an osteogenesis‐related molecule and thought to be implicated in tooth growth. Bone morphogenetic protein‐1 BMP ‐1) contributes development by the degradation of dentin‐specific substrates a metalloprotease. In this study, we demonstrated correlations between ‐1 human carious teeth subcellular dynamics dental pulp cells. Materials Methods Expression was analyzed immunohistochemistry. ‐1‐induced protein...
Plasminogen activator (PA) is the enzyme responsible for converting plasminogen to its active form, plasmin, which involved in various physiological and pathological phenomena. PA exists two forms: urokinase-type (uPA) tissue-type (tPA). Here we investigated effect of inflammatory cytokine tumor necrosis factor α (TNF-α) on production secretion human dental pulp cells. When cells were stimulated with TNF-α (10 ng/mL), activity medium clearly increased a time-dependent manner, this was...
Introduction: Vertical root fractures (VRFs) in endodontic treatment teeth are most serious complication.VRFs have a poor prognosis and usually result tooth extraction.The purpose of this study was to evaluate the clinical outcomes mineral trioxide aggregate (MTA) -filled for VRFs using by dental operate microscope (DOM).Methods: Fifty-two with were evaluated.52 examined evaluated finding radiography, DOM canal.The MTA-filled adhesion methods consist elimination infected dentin ultrasonic...
Altered mental status is a common, yet challenging, clinical presentation encountered by physicians. Here, we report case of 68-year-old Japanese female who was transferred to the emergency department due faint. The laboratory results showed hyponatremia, ketonuria, hyperglycemia and acute kidney injury without fever or inflammatory findings. Although these abnormalities were corrected, her exacerbated, apnea/tachypnea appeared. She eventually diagnosed with apical abscess recovered...