Laura Guerra

ORCID: 0000-0002-7105-0035
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About
Contact & Profiles
Research Areas
  • Allergic Rhinitis and Sensitization
  • Asthma and respiratory diseases
  • Respiratory and Cough-Related Research
  • Urticaria and Related Conditions
  • Dermatology and Skin Diseases
  • Food Allergy and Anaphylaxis Research
  • Cervical Cancer and HPV Research
  • Global Cancer Incidence and Screening
  • Bariatric Surgery and Outcomes
  • Diet and metabolism studies
  • Drug-Induced Adverse Reactions
  • Pharmaceutical Practices and Patient Outcomes
  • Receptor Mechanisms and Signaling
  • Neonatal Respiratory Health Research
  • Pharmaceutical studies and practices
  • Opioid Use Disorder Treatment
  • Organ Transplantation Techniques and Outcomes
  • Pain Management and Opioid Use
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Cardiac electrophysiology and arrhythmias
  • Renal Transplantation Outcomes and Treatments
  • Transplantation: Methods and Outcomes
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Mast cells and histamine
  • Pharmacology and Obesity Treatment

Ospedale Policlinico San Martino
2024

Texas State Technical College Harlingen
2023

The University of Texas MD Anderson Cancer Center
2002-2023

Harris Health System
2023

The University of Texas Health Science Center at Houston
2023

Universidad del Norte
2023

Escola Bahiana de Medicina e Saúde Pública
2023

New York City Health and Hospitals Corporation
2022

Centers for Disease Control and Prevention
2022

Ministry of Health
2022

Background: Health‐related quality of Life in patients with chronic urticaria is evaluated by mean generic instruments or questionnaire designed for skin diseases. No disease‐specific tool now available the assessment impact from patients’ viewpoint. Objective: The aim our study to develop and validate a new specifically life (Chronic Urticaria Quality Questionnaire – CU‐Q 2 oL) Methods: In development phase oL an initial list items 37 was compiled given 80 urticaria; 23 most significant...

10.1111/j.1398-9995.2005.00833.x article EN Allergy 2005-06-21

Background: Few articles are available about chronic urticaria (CU) impact on patients’ quality of life (QoL). The aim our study was to evaluate QoL in CU patients both focusing health status and subjective satisfaction. We adopted two generic tools: SF‐36 (an questionnaire) SAT‐P (a satisfaction profile). Methods: Twenty‐one untreated (five males, 16 females; aged 46.3 ± 12.4) affected by CU, were enrolled. scores compared with a group 27 respiratory allergy. Published reference values 608...

10.1034/j.1398-9995.2003.00091.x article EN Allergy 2003-06-24

Abstract Climacostol, a compound produced by the ciliated protozoan Climacostomum virens , displayed cytotoxic properties in vitro . This study demonstrates that it has anti-tumour potential. Climacostol caused reduction of viability/proliferation B16-F10 mouse melanoma cells, rapidly occurring DNA damage, and induced intrinsic apoptotic pathway characterised dissipation mitochondrial membrane potential, translocation Bax to mitochondria, release Cytochrome c from activation Caspase...

10.1038/srep27281 article EN cc-by Scientific Reports 2016-06-07

1. We used electrophysiological and binding techniques to determine the effects of oxygen free radicals (OFRs) generated by dihydroxyfumaric acid (DHF, 5 mM) on calcium current dihydropyridine sites in guinea-pig isolated ventricular myocytes. 2. Binding [3H]-PN200-110 myocytes revealed one population with a KD 0.11 +/- 0.01 nM Bmax 139.1 6.9 fmol mg-1 protein (n = 24). After 15 min exposure DHF, density, but not affinity was significantly (P < 0.01) reduced 35% control value (Bmax 49.4 3.7...

10.1111/j.1476-5381.1996.tb15534.x article EN British Journal of Pharmacology 1996-07-01

A variety of surgical procedures have been developed to accelerate orthodontic treatment adult patients seeking enhance their smiles or masticatory function. While most these techniques are invasive, the minimally invasive piezocision technique reduces trauma by combining microincisions and localized piezoelectric bone surgery. method for with use computed tomography is presented here. By creating a three-dimensional model arch, depth location corticotomies can be precisely planned, guide...

10.11607/prd.1741 article EN The International Journal of Periodontics & Restorative Dentistry 2014-07-01

ABSTRACTBackground: Allergic rhinitis is a high-prevalence disease that affects quality of life (QOL), sleep and productivity patients. According to the ARIA initiative, it classified as intermittent persistent, latter being most troublesome.Methods: The aim this randomized, open-label, 6-month, pilot study was determine whether levocetirizine 5 mg administered continuously once daily in morning better than on-demand symptomatic subjects with persistent allergic rhinitis. Total individual...

10.1185/03007990802395927 article EN Current Medical Research and Opinion 2008-08-29

Contact tracing is a core strategy for preventing the spread of many infectious diseases public health concern. Better understanding outcomes contact COVID-19 as well operational opportunities and challenges in establishing program jurisdiction large New York City (NYC) important evaluation this strategy.To describe establishment, scaling, maintenance Trace, NYC's program, share data on during its first 17 months.This cross-sectional study included people with laboratory test-confirmed...

10.1001/jamanetworkopen.2022.39661 article EN cc-by-nc-nd JAMA Network Open 2022-11-02

&lt;i&gt;Background:&lt;/i&gt; Desloratadine (DL) and levocetirizine (LCZ) are the newest commercialized antihistamines. Pharmacokinetics, pharmacodynamics clinical data available for both drugs, but there is to date no direct comparison involving nose skin at same time. We compared effects of a single dose two drugs in over 24 h. &lt;i&gt;Methods:&lt;/i&gt; Twenty-three patients with symptomatic allergic rhinitis were enrolled randomized double-blind crossover administration DL LCZ. The...

10.1159/000080657 article EN International Archives of Allergy and Immunology 2004-01-01

Background: Tacrolimus is the primary calcineurin inhibitor used in immunosuppressive regimens to prevent allograft rejection (AR) after organ transplantation. Recent studies have linked intrapatient variability (IPV) of tacrolimus with AR occurrence and reduced survival, especially kidney transplant recipients. However, limited data are available on impact IPV adverse outcomes liver transplantation (LT). Aims: The aim this study was assess association between using various methodologies...

10.1097/ftd.0000000000001192 article EN Therapeutic Drug Monitoring 2024-03-29

&lt;i&gt;Background:&lt;/i&gt; Adverse reactions to drugs are common in the clinical practice. Many outpatients frequently referred allergists order determine which they can safely take future. &lt;i&gt;Objective:&lt;/i&gt; We set up an oral single-dose tolerance test procedure find out for each patient one or more alternative that be taken when needed. &lt;i&gt;Methods:&lt;/i&gt; 452 (130 male, 322 female) with well-documented (urticaria/angioedema, respiratory symptoms, laryngeal edema,...

10.1159/000066777 article EN International Archives of Allergy and Immunology 2002-01-01
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