A5069647602- SARS-CoV-2 and COVID-19 Research
- Bioactive Compounds and Antitumor Agents
- Nigella sativa pharmacological applications
- Computational Drug Discovery Methods
- Effects of Environmental Stressors on Livestock
- Bone health and treatments
- Tissue Engineering and Regenerative Medicine
- Essential Oils and Antimicrobial Activity
- Thyroid and Parathyroid Surgery
- Insect and Pesticide Research
- Phytochemistry and Bioactivity Studies
- Reproductive Physiology in Livestock
- Chemotherapy-induced organ toxicity mitigation
- Phytochemistry and Biological Activities
- Medicinal Plant Extracts Effects
- Anatomy and Medical Technology
- Thyroid Disorders and Treatments
- Genetic and phenotypic traits in livestock
- Drug-Induced Hepatotoxicity and Protection
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Bee Products Chemical Analysis
- Olfactory and Sensory Function Studies
Bezmiâlem Vakıf Üniversitesi
2019-2024
Istanbul University
2023
Coronavirus disease 2019 (COVID-19) is an infectious caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in a vast number of infections and deaths that deeply affect the world. When virus encounters host cell, it binds to angiotensin-converting enzyme 2, then S protein broken down transmembrane protease serine with help furin, allowing enter cell. The elevated inflammatory cytokines suggest cytokine storm, also known as release syndrome, may play major role...
Background: Melissa officinalis L. (MO), commonly known as lemon balm, a member of the mint family, is considered calming herb. In various traditional medicines, it has been utilized to reduce stress and anxiety promote sleep. A growing body clinical evidence suggests that MO leaf extract supplementation possesses considerable neuropharmacological properties. However, its possible mechanism action largely remains unknown. Objective: present in vitro studies, we comparatively investigated...
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) poses ongoing global health challenges due to its propensity for mutations, which can undermine vaccine efficacy. With no definitive treatment available, urgent research into affordable and biocompatible therapeutic agents is extremely urgent. Angiotensin converting enzyme-2 (ACE-2), transmembrane protease serine subtype (TMPRSS2), Furin enzymes, allow the virus enter cells, are particularly important as potential drug targets...
In this study, we investigated the combined treatment of 5-fluorouracil (5-FU) and Anatolian propolis extract (PE) on colorectal cancer (CRC)using in vitro vivo studies. We exposed luciferase-transfected (Lovo-Luc CRC) cells healthy colon (CCD-18Co) to varying concentrations 5-FU PE assess their genotoxic, apoptotic, cytotoxic effects, as well intracellular reactive oxygen species (iROS) levels. also developed a xenograft model nude mice evaluated anti-tumor effects using various methods....
Background: Cancer is a life-threatening condition with an economic burden on societies. Phytotherapy rapidly taking place in cancer research to increase the success of treatment and quality life. Thymoquinone (TQ) main active phenolic compound obtained from essential oil Nigella sativa (black cumin) plant seed. For long time, black cumin has been used traditionally for remedy different diseases because its various biological effects. It shown that most these effects seeds are due TQ. TQ...
Aim: Glioblastoma, known for its aggressiveness, accounts most malignant gliomas and the efficiency of treatment is still not enough showing remarkably poor prognosis even though a complex approach. Hedera helix an evergreen plant mostly effects on respiratory function, especially in chronic bronchial asthma, as well antimicrobial, anti-inflammatory, antioxidant, potential antitumor properties, while effect glioblastoma cancer underlying mechanism has been elucidated yet. The aim this study...
Amaç: Çalışmamızın amacı, insan paratiroid dokularından izole edilen hiperplazik hücrelerin, sıçanlara immünsupresan verilmeden transplante edilerek transplantasyon verimliliğinin incelenmesidir. Gereç ve Yöntem: Çalışmada, hiperplazi tanısıyla opere 62 yaşında erkek hastadan hücreleri kullanıldı. Alıcı olarak üç adet Sprague Dawley sıçan İnsandan elde hücreler uygulanmadan edildi. Transplantasyon işlemi sırasında doğrudan sırasıyla, vena portaya, cavaya periferik vene enjekte başarısının...