Xinya Bu

ORCID: 0000-0002-7130-1105
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About
Contact & Profiles
Research Areas
  • DNA and Nucleic Acid Chemistry
  • DNA Repair Mechanisms
  • Drug Transport and Resistance Mechanisms
  • Plant Virus Research Studies
  • Fluorine in Organic Chemistry
  • Click Chemistry and Applications
  • Polyomavirus and related diseases
  • Metal complexes synthesis and properties
  • Amino Acid Enzymes and Metabolism
  • Axial and Atropisomeric Chirality Synthesis
  • Cyclopropane Reaction Mechanisms
  • Cancer Research and Treatments
  • RNA Interference and Gene Delivery
  • Radioactive element chemistry and processing

University of Chinese Academy of Sciences
2022

Weatherford College
2020

Shenyang University of Chemical Technology
2020

Robert Bosch (Germany)
2020

University of Missouri
1996

An early step in the initiation of polyomavirus DNA replication is viral large-T-antigen-mediated unwinding origin. We report that components AP1 transcription factor, Fos and Jun, interact with T antigen vitro to enhance This provides a biochemical basis for capacity activate vivo.

10.1128/jvi.70.8.4914-4918.1996 article EN Journal of Virology 1996-08-01

DNA damage can occur naturally or through environmental factors, leading to mutations in replication and genomic instability cells. Normally, natural d-nucleotides were selected by polymerases. The template l-thymidine (l-T) has been shown be bypassed several types of However, fidelity nucleotide incorporation opposite vivo remains unknown. Here, we constructed plasmids containing a restriction enzyme (PstI) recognition site which the l-T lesion was site-specifically located within PstI...

10.1021/acs.chemrestox.9b00502 article EN Chemical Research in Toxicology 2020-08-19

Ion ChannelsA voltage-responsive synthetic Cl À channel regulated by pH is demonstrated M. Barboiu et al. in their Communication on page 18920.The dual voltage/pH system represents an unexplored alternative for ion pumping along artificial channels.

10.1002/anie.202084311 article EN Angewandte Chemie International Edition 2020-10-12

Abstract Enantiomers of chiral substances typically have distinct biological activities, thus, the explorations biochemical processes at enantiomeric level has very high significance. This study investigated DNA polymerase–catalyzed reaction modulated by various types cobalt complexes. The experimental data showed that polymerase reactions were inhibited or accelerated in presence K[Co(edta)] ⋅ 2H 2 O [Co(en) 3 ]I H O. More importantly, stereocontrol bioreactivity was found to be different...

10.1002/adsc.202200418 article EN Advanced Synthesis & Catalysis 2022-06-13

ADVERTISEMENT RETURN TO ISSUEPREVAddition/CorrectionNEXTORIGINAL ARTICLEThis notice is a correctionCorrection to Replication of DNA Containing Mirror-Image Thymidine in E. coli CellsYuhe KanYuhe KanMore by Yuhe Kan, Lu ChenLu ChenMore Chen, Dao LinDao LinMore Lin, Xinya BuXinya BuMore Bu, Mengwu MoMengwu MoMore Mo, Liang YanLiang YanMore Yan, Zhenjun YangZhenjun YangMore Yanghttp://orcid.org/0000-0001-7614-595X, Longfei Yuan*Longfei YuanMore Yuan, Li Wu*Li WuMore...

10.1021/acs.chemrestox.0c00520 article EN Chemical Research in Toxicology 2021-01-04
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