A5032863497- Pneumocystis jirovecii pneumonia detection and treatment
- HIV/AIDS drug development and treatment
- Venous Thromboembolism Diagnosis and Management
- Pneumonia and Respiratory Infections
- Acute Myocardial Infarction Research
- Atrial Fibrillation Management and Outcomes
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Heart Failure Treatment and Management
- Health Systems, Economic Evaluations, Quality of Life
- Bone health and osteoporosis research
- Central Venous Catheters and Hemodialysis
- Geological and Geochemical Analysis
- Tuberculosis Research and Epidemiology
- Chronic Disease Management Strategies
- Emergency and Acute Care Studies
- Geology and Paleoclimatology Research
- Diagnosis and Treatment of Venous Diseases
- Cardiovascular and exercise physiology
- Hip and Femur Fractures
- Planetary Science and Exploration
- Pediatric Pain Management Techniques
- Pain Management and Opioid Use
- Landslides and related hazards
- Bone and Joint Diseases
- Peptidase Inhibition and Analysis
Fondazione FADOI
2014-2025
University of Bari Aldo Moro
1997-2016
Ospedali Riuniti Umberto I
2014
University of Bologna
1997-2011
Luigi Sacco Hospital
2001-2007
University of Ferrara
1997-1998
Patients with acute exacerbations of chronic obstructive pulmonary disease (COPD) are often hospitalized in internal medicine units (IMUs), and their management is challenging due to a multiplicity factors affecting the outcome, such as correct patient classification, appropriate pharmacologic therapy, discharge, follow-up. In this context, standardized pathway (algorithm) for these patients was designed tested. Specifically, based on information collected through survey COPD IMUs, an...
Mutations in the human-derived Pneumocystis carinii dihydropteroate synthase (DHPS) gene have been reported with increasing frequency and linked to prior sulfa prophylaxis possible emergence of resistance. This study was done examine prevalence clinical significance P. DHPS mutations Italian patients. A previously described single-strand conformation polymorphism technique used identify 107 patients acquired immunodeficiency syndrome. Overall (8%) low compared that other reports. were...
Background: Two Pneumocystis jiroveci independent genomic regions, internal transcribed spacer (ITS) 1 and ITS2, dihydropteroate synthase (DHPS) gene have been used for typing a cohort of HIV-infected Italian patients with P. pneumonia (PcP). Methods: Bronchoalveolar lavage samples isolated from 207 adults were ITS DHPS genotyped by DNA sequencing restriction fragment length polymorphism analysis, respectively. Mutant cloned typed. Data on severity, treatment, outcome PcP obtained chart...
Abstract Background The burden of cardiovascular (CV) complications in patients hospitalised for community-acquired pneumonia (CAP) is still uncertain. Available studies used different designs and criteria to define CV complications. We assessed the cumulative incidence acute during hospitalisation CAP Internal Medicine Units (IMUs). Methods This was a prospective study carried out 26 IMUs, enrolling consecutively CAP. Defined were: newly diagnosed heart failure, coronary syndrome, new onset...
Hospitalised medical patients are at increased risk of venous thromboembolism (VTE), but the incidence hospitalisation-related VTE in unselected inpatients has not been extensively studied, and uncertainties remain about optimal use thromboprophylaxis this setting. Aims our prospective, observational study were to assess prevalence symptomatic, events a cohort consecutive admitted 27 Internal Medicine Departments, evaluate clinical factors associated with thromboprophylaxis. Between March...
We propose a model to describe lava tube formation, considering as Newtonian fluid moving downslope in rectangular channel. obtain flow velocity using an analytical steady‐state solution of the Navier‐Stokes equation. Shear stress is also calculated from for incompressible and isotropic fluid. A 2‐D with heat flux assigned at upper surface introduced cooling by radiation into atmosphere temperature. Lava crust considered plastic body, its rheology described through introduction yield...
Summary Few studies have addressed the topic of venous thromboembolism (VTE) in patients hospitalised rehabilitation facilities. This patient population is rapidly growing, and data aimed to better define VTE risk this setting are needed. Primary aim prospective observational study was evaluate frequency symptomatic, objectively confirmed a cohort unselected consecutive admitted facilities, after medical diseases or surgery. Further objectives were assess overall mortality, identify factors...
Wireless vital parameter continuous monitoring (WVPCM) after discharge is compared to regular provide data on the clinical-economic impact of complex patients (CPs) discharged from Internal Medicine Units Ospedale dei Castelli, Lazio.Major complications (MC) reduction.Patients who reached criteria within 7th day admission; difference in MC incidence at conclusion standard telemonitoring/clinical phase, 5 and 30 days discharge; conditions predisposing occurrence.Open label randomized...
Atrial fibrillation is the most frequent arrhythmia, but few data are available on patients' characteristics and management in context of Internal Medicine wards.Data were collected at beginning 2010 18 units regions Liguria Piemonte (Italy). Each centre reviewed hospital charts last 50 patients discharged during year 2009 whom a diagnosis atrial had been made (patient's history or hospitalization).A total 903 evaluated. Prevalence among hospitalized was 18.2%. More than 85% least two...
The chronic course and evolution of obstructive pulmonary disease (COPD) is often characterized by periods exacerbation symptoms, which have a negative impact on the quality life patients, as well COPD, represent significant cause medical intervention hospitalization. Very few data are available efficacy rescue antibiotics in patients with acute COPD (AECOPD) unresponsive to previous treatment. aim this study was evaluate two fluoroquinolones AECOPD previously treated without success....
Venous thromboembolism (VTE) in hospitalized medically ill patients is a significant cause of morbidity and mortality. Guidelines suggest that VTE bleeding risk assessment models (RAMs) should be integrated into the clinical decision-making process on thromboprophylaxis. However, poor evidence available comparing use RAM versus judgement evaluating occurrence.
The introduction of protease inhibitors (PIs) gave a dramatic drop in AIDS-related opportunistic events, mainly due to induced immune reconstitution. Discontinuation prophylaxis against Pneumocystis carinii is considered safe when CD4 > 200 cells/mm3. Ideally, we should have specific functional tests for HIV-1-related decisions. We examined viro-immunological profiles, clinical outcome and lymphocyte proliferation (LP) P. other antigens 108 subjects: 28 AIDS presenters with pneumonia (PCP)...
Bends in lava channels are often observed volcanic fields. The curvature of a channel affects flow dynamics and surface morphology may be trigger for the formation tube. We propose model to describe effects on velocity, shear stress crust at surface. Lava is described as Newtonian, homogeneous, isotropic incompressible fluid. steady-state solution Navier-Stokes equation found unidirectional flow, cylindrical coordinates. levees arcs concentric circumferences, with their centres origin...
Patients with peripheral arterial disease (PAD) at stage IIb, pain-free walking distance (PFWD) less than 100 m and unsuitable for revascularization have both impaired quality of life severe clinical outcome. Aim the study was to evaluate efficacy prostacyclin analogue iloprost, added standard therapy, in these patients.Patients were randomized receive medical therapy (Group A) or plus iloprost B), 1 year. Iloprost administered 10 days every 3 months. Treadmill test performed months, Group B...
An amendment to this paper has been published and can be accessed via the original article.
We propose a model to explain lava tube formation by the growth of crust slabs from levees channel toward its center, involving solid surface fragments. The flow dynamics are described with steady state solution Navier‐Stokes equation in rectangular channel, for Newtonian, homogeneous, isotropic and incompressible fluid. cooling is mechanism heat conduction into atmosphere. presence taken account both dynamical thermal model. As long as cools, layer forms at surface, much thicker near than...
Post-discharge prophylaxis for venous thromboembolism (VTE) is a challenging issue in patients hospitalised Internal Medicine Units (IMUs). The aim of this study was to evaluate the frequency and factors associated with post-discharge VTE IMUs. Multi-centre, retrospective including consecutive who were admitted any cause discharged from an IMU. Overall, 3,740 (mean age 74.1 ± 15.7 years) included at 38 IMUs Italy. At discharge, percentage receiving pharmacological thromboprophylaxis 16.0%...
We present here the results from dynamical and thermal models that describe a channeled lava flow as it cools by radiation. In particular, effects of power-law rheology presence bends in are considered, well formation surface crust tubes. On basis models, we analyze assumptions implicit currently used formulae for evaluation rates satellite imagery. Assuming steady down an inclined rectangular channel, solve numerically equation motion finite-volume method classical iterative solution. Our...
Purpose Few real-world data are available on the frequency and management of pain in Internal Medicine (IM). Aims our study were to assess prevalence IM, evaluate effects a standardised educational programme. Materials methods The was performed 26 IM Units Italy, with two cross-sectional surveys (PRE phase POST phase) interspersed an In PRE each Centre reviewed hospital charts last 100 consecutive patients hospitalised for any cause. An programme conducted by means ‘outreach visit’,...
Several studies show that physical activity can reduce the risk of cardiovascular disease, but vast majority these focus on short- to intermediate-term benefits or refer very specific populations. This observational study was conducted determine whether performed during third fourth decade life influences occurrence events in patients aged 65-75 years. We studied a cohort 2191 unselected admitted Internal Medicine Departments. Data were collected patients' medical history and their level...
Purpose: The study aims at assessing the organizational and economic impact related to use of a new portable syringe pump (Pompa Infonde®, Italfarmaco S.p.A., Cinisello Balsamo, Italy) hospital level. Methodology: Based on HTA approach, analysis assessed device level, using traditional methods Iloprost infusion as comparator. After pilot evaluation, was within 24 Italian hospitals. Structured interviews were conducted with clinicians nurses. According Hospital-Based questionnaire human...