Jan Tůma

ORCID: 0000-0002-7197-8482
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About
Contact & Profiles
Research Areas
  • Pediatric Urology and Nephrology Studies
  • Radiomics and Machine Learning in Medical Imaging
  • Medical Imaging and Pathology Studies
  • Ultrasound in Clinical Applications
  • Appendicitis Diagnosis and Management
  • Renal cell carcinoma treatment
  • Medical Practices and Rehabilitation
  • Education, Psychology, and Social Research
  • Structural Analysis and Optimization
  • Renal and Vascular Pathologies
  • Lung Cancer Diagnosis and Treatment
  • Otolaryngology and Infectious Diseases
  • Structural Load-Bearing Analysis
  • Omental and Epiploic Conditions
  • Genetic Neurodegenerative Diseases
  • Mitochondrial Function and Pathology
  • Intestinal and Peritoneal Adhesions
  • Gastrointestinal disorders and treatments
  • Salivary Gland Tumors Diagnosis and Treatment
  • Renal and related cancers
  • Medical Imaging Techniques and Applications
  • Radiology practices and education
  • MRI in cancer diagnosis
  • Kidney Stones and Urolithiasis Treatments
  • Structural Engineering and Vibration Analysis

Charles University
2013-2025

The University of Texas Health Science Center at San Antonio
2020-2025

Klinik Hirslanden
2013-2022

College of Physical Education and Sport Palestra
2018

Vysoká Škola Zdravotníctva a Sociálnej Práce sv. Alžbety
2018

Spital Uster
2008-2017

John Wiley & Sons (Germany)
2015

Institute of Chemical Technology
2014

University of Chemistry and Technology, Prague
2013-2014

Czech Aerospace Research Centre
2013

To improve the adhesive properties of artificial fibrillar contact structures, attachment systems beetles from family Chrysomelidae were chosen to serve as a model. Biomimetic mushroom-shaped microstructure inspired by these was characterized using variety measurement techniques and compared with control flat surface made same material. Results revealed that pull-off force peel strength structured specimens are more than twice those specimens. In contrast system, one is found be very...

10.1098/rsif.2006.0164 article EN Journal of The Royal Society Interface 2006-10-17

Neurological disorders are often debilitating conditions with no cure. The majority of current therapies palliative rather than disease-modifying; therefore, new strategies for treating neurological greatly needed. mRNA-based therapeutics have great potential such disorders; however, challenges delivery limited their clinical potential. Lipid nanoparticles (LNPs) a promising vector the brain, given safer toxicity profile and higher efficacy. Despite this, very little is known about...

10.1021/acs.biochem.3c00371 article EN Biochemistry 2023-09-20

Abstract Fragile X syndrome (FXS) is a neurodevelopmental disorder oftentimes associated with abnormal social behaviors and altered sensory responsiveness. It hypothesized that the inappropriate filtering of stimuli, including olfaction, can lead to aberrant behavior in FXS. However, previous studies investigating olfaction animal models FXS have shown inconsistent results. Here, we found Fmr1 knock-out (KO) mice, mouse model FXS, showed increased sniffing duration for non-social odors...

10.1038/s41598-024-80000-5 article EN cc-by Scientific Reports 2025-01-23

Algebra. Geometry. Trigonometry. Plane Analytic Space Elementary Functions. Differential Calculus. Sequences and Series. Integral Vector Analysis. Functions of a Complex Variable. Fourier Higher Transcendent Ordinary Equations. Partial Laplace Transforms. Numerical Methods. Probability Statistics. Table Indefinite Integrals. Tables Definite Curves Areas. Surfaces. Appendices: A: Tables. B: Glossary Symbols Mathematics Terms. C: Units Measurement Conversions Between International U. S....

10.5860/choice.36-0351 article EN Choice Reviews Online 1998-09-01

10.2307/1267189 article EN Technometrics 1971-08-01

10.1007/bf02892211 article EN Československá Mikrobiologie 1958-03-01

Acetylcholinesterase (AChE) rapidly hydrolyzes acetylcholine. At the neuromuscular junction, AChE is mainly anchored in extracellular matrix by collagen Q, whereas brain, tethered proline-rich membrane anchor (PRiMA). The AChE-deficient mice, which has been deleted from all tissues, have severe handicaps. Surprisingly, PRiMA KO mice mostly eliminated brain show very few deficits. We now report that most of changes observed and particular high levels ambient acetylcholine massive decrease...

10.1111/j.1471-4159.2012.07856.x article EN Journal of Neurochemistry 2012-07-02

10.1007/bf02874190 article EN Folia Microbiologica 1964-11-01

The cerebellum is not only essential for motor coordination but also involved in cognitive and affective processes. These functions of the mechanisms their disorders cerebellar injury are completely understood. There a wide spectrum mutant mice which used as models hereditary degenerations. Nevertheless, they differ pathogenesis manifestation particular mutation strain background. aim this work was to compare spatial navigation, learning, memory pcd Lurcher mice, two most frequently mutants....

10.3389/fnbeh.2015.00116 article EN cc-by Frontiers in Behavioral Neuroscience 2015-05-12

10.1007/bf02878845 article EN Folia Microbiologica 1966-03-01

10.1115/1.3423276 article EN Journal of Applied Mechanics 1974-03-01

Protein-based therapeutics have the potential to treat a variety of diseases, however, safe and effective methods for delivering them into cells need be developed before their clinical can realized. Peptide fusions great improving intracellular delivery proteins. However, very few peptides been identified that increase proteins, new enhance protein are greatly needed. In this report, authors demonstrate coiled-coil forming peptide (KVSALKE)

10.1002/adhm.202102118 article EN Advanced Healthcare Materials 2021-12-03
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