A5048904027- Thyroid Cancer Diagnosis and Treatment
- Parathyroid Disorders and Treatments
- Thyroid and Parathyroid Surgery
- Bariatric Surgery and Outcomes
- Thyroid Disorders and Treatments
- Head and Neck Anomalies
- Genetic factors in colorectal cancer
- Gastrointestinal disorders and treatments
- Voice and Speech Disorders
- Colorectal Cancer Screening and Detection
- Medical Imaging and Pathology Studies
- Diverticular Disease and Complications
- Genetic Syndromes and Imprinting
- Esophageal and GI Pathology
- Cardiovascular Disease and Adiposity
- Colorectal Cancer Surgical Treatments
- Pancreatic and Hepatic Oncology Research
- Neuroendocrine Tumor Research Advances
- Metastasis and carcinoma case studies
- Airway Management and Intubation Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Gastric Cancer Management and Outcomes
- Growth Hormone and Insulin-like Growth Factors
- Gastrointestinal Tumor Research and Treatment
- Helicobacter pylori-related gastroenterology studies
University of Brescia
2016-2025
Aziende Socio Sanitarie Territoriali di Lecco
2023
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
2003-2019
Ospedale Policlinico San Martino
2013
Brescia University
2005
Peptic ulcer disease is common with a lifetime prevalence in the general population of 5-10% and an incidence 0.1-0.3% per year. Despite sharp reduction rates hospital admission mortality over past 30 years, complications are still encountered 10-20% these patients. remains significant healthcare problem, which can consume considerable financial resources. Management may involve various subspecialties including surgeons, gastroenterologists, radiologists. Successful management patients...
Abstract Background Primary hyperparathyroidism is an endocrine pathology that affects calcium metabolism. Patients with primary have high concentrations of serum or parathyroid hormone, incorrect hormone levels for values. due to the presence adenoma/single-gland disease in 80–85%. Multiple gland hyperplasia accounts 10–15% cases hyperparathyroidism. Atypical adenoma and carcinoma are both responsible about 1.2–1.3% 1% less hyperparathyroidism, respectively. Methods We performed a...
Structural alterations of subcutaneous small resistance arteries, as indicated by an increased media:lumen ratio, are frequently present in hypertensive and/or diabetic patients and may represent the earliest alteration observed. In addition, ratios arteries have a strong prognostic significance. However, no data available about structure obese patients, particularly after weight loss. We investigated 27 with severe obesity. Twelve them were normotensive, 15 hypertensive. All underwent...
Drug malabsorption is a potential concern after bariatric surgery. We present four case reports of hypothyroid patients who were well replaced with thyroxine tablets to euthyroid thyrotropin (TSH) levels prior Roux-en-Y gastric bypass These developed elevated TSH the surgery, responded reversibly switching from treatment oral liquid formulation.
The aim of this study was to evaluate the predictive value sonography and sonographic elastography in thyroid nodules with nondiagnostic cytologic findings.The included 101 patients (74 female, mean age ± SD, 55 11 years [range, 27-70 years]; 27 male, age, 62 9 42-72 years]) who had at least 1 nodule findings two different fine-needle aspiration evaluations an indication for hemi or total thyroidectomy clinical suspicion malignancy, size, occurrence a coexisting suspicious malignancy. All...
Angiogenesis plays a crucial role in tumor growth and progression. Low expression of mineralocorticoid receptor (MR) several malignant tumors correlates with disease recurrence overall survival. Previous studies have shown that MR is decreased colorectal cancer (CRC). Here we hypothesize can contribute to angiogenesis poor patient survival malignancies. In cohort CRC patients, analyzed expression, its correlation microvascular density impact on Subsequently, interrogated the an vitro model,...
Background: The recurrent laryngeal nerve (RLN) can be injured during thyroid surgery, which negatively affect a patient's quality of life. impact intraoperative anatomic variations the RLN on injury remains unclear. Objectives this study were to (1) better understand detailed surgical variability with worldwide perspective; (2) establish potential correlates between anatomy and electrophysiologic responses; (3) use information minimize complications assure accurate safe neuromonitoring...
Graves' disease can occur as an isolated condition or part of autoimmune polyglandular syndrome; there are no data regarding the differences in phenotype between these two forms. To assess clinical presentation, complications, and outcomes patients with compared to those whom is syndrome. GRAPHE study a retrospective observational study. The medical records all diagnosed regularly followed at outpatient clinics for Endocrinology, Nuclear Medicine Clinical Surgery, from January 1, 2010, June...
Liquid ethanol-containing levothyroxine (e-LT4) is known to circumvent malabsorption induced by food, drugs, or pathological conditions. Recently a new ethanol-free formulation of liquid (ef-LT4) has been commercialized. No studies have compared e-LT4 with ef-LT4. The aim the present study compare thyroid hormone profile in patients treated and We retrospectively retrieved hormonal clinical data 48 diagnosed hypothyroidism who had on stable treatment an e- LT4 at same dosage for least one...
Although 99m Technetium-sestamibi scintigraphy with single-photon emission computed tomography (SPECT) and, recently, hybrid SPECT/computed (CT) have been claimed to be the preoperative methods of choice for parathyroid localization in patients primary hyperparathyroidism (PHPT) and concomitant nodular goiter (NG), they never compared this setting. We aimed at testing hypothesis that SPECT/CT may superior SPECT PHPT NG.Thirty-three NG (one or more lesions based on cervical ultrasound) who...
It is not known whether, in obesity, the capillary density or number of circulating endothelial progenitor cells (EPCs) are reduced, whether fibrosis small vessels also present. In addition, possible effects weight reduction on these parameters have never been evaluated. Therefore, we investigated EPCs and 25 patients with severe all submitted to bariatric surgery, 18 normotensive lean subjects 12 hypertensive as controls. All underwent a biopsy subcutaneous fat during surgery. five...
Abstract Background. The objective of this study was to identify the preoperative risk factors for patients in need a sternotomy management mediastinal goiters order provide better planning and patient consent. Methods. We analyzed 98 who underwent surgery (goiters extending below thoracic inlet ≥3 cm with neck hyperextension) between 1995 2008. Twelve (12.2%) required sternotomy. patients' features were by surgical approach performed. Logistic regression analysis used which variables...
We aimed to evaluate the impact of loupe magnification (LM) on incidental parathyroid gland removal (from pathology reports), hypocalcemia, and recurrent laryngeal nerve (RLN) injury after total thyroidectomy answer question whether this tool should be always recommended for patient's safety. Between January 2005 December 2008, 126 patients underwent with routine use 2.5 x galilean loupes; their charts were compared data 118 operated between 1997 2000 without LM (two different equally...
Background . Toshiba Medical System has developed a new Doppler technique [Superb Microvascular Imaging (SMI)] that improved microvascular flow imaging. SMI depicts perinodular and intranodular thyroid in higher detail compared to standard colour (CD) power (PD) Objective Assess the nodular architecture by CD PD features series of nodules submitted fine needle aspiration cytology, order evaluate potential detecting cancer. Materials Methods From April 2016 July 2017, 254 patients with...
In October 2016 the American Joint Committee on Cancer (AJCC) published 8th edition of AJCC/TNM cancer staging system and it has been introduced in clinical practice since 1st January 2018. The effect most changes new was downstaging a significant number patients into lower stages, reflecting their low risk thyroid cancer-related death. One relevant modification refers to role microscopic extra-thyroidal tumor invasion, which is no longer considered as criterion for classification T3 tumors....
Background . Recently, it has been shown that liquid L-T4 formulation can be ingested with breakfast. This study looked to extend these findings by investigating whether a soft gel capsule of could also at breakfast time. Methods 60 patients (18–65 yrs), previously submitted thyroidectomy for proven benign goitre in stable euthyroidism receiving therapy breakfast, were enrolled. TSH, fT4, and fT3 levels assessed all the who switched from same dosage L-T4. After 6 months, determined again....
Background Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal neoplasms of gastrointestinal tract. More rarely with histology and immunohistochemistry similar to GISTs may occur outside tract (omentum, mesentery retroperitoneum) so-called Extra-gastrointestinal Stromal Tumors (EGISTs). EGISTs arising in retroperitoneum extremely rare: date, only 58 cases have been reported literature. Case Report We herein report a case primary EGIST surgically treated. The pre-operative...