A5028992958- Diet and metabolism studies
- Gut microbiota and health
- Nutritional Studies and Diet
- Nutrition and Health in Aging
- Health, psychology, and well-being
- Cancer-related molecular mechanisms research
- Liver Disease Diagnosis and Treatment
- RNA modifications and cancer
- Telomeres, Telomerase, and Senescence
- Liver physiology and pathology
- RNA Research and Splicing
- Tryptophan and brain disorders
Hospital Universitario Reina Sofía
2020-2025
University of Córdoba
2020-2025
Instituto Maimónides de Investigación Biomédica de Córdoba
2020-2025
Instituto de Salud Carlos III
2024-2025
Surgical Science (Sweden)
2025
Centro de Investigación Biomédica en Red
2024
Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition
2020
Abstract Background Cardiovascular diseases (CVD), including coronary heart disease (CHD), display a higher prevalence in men than women. This study aims to evaluate the variations intestinal microbiota between and women afflicted with CHD delineate these against non-CVD control group for each sex. Methods Our research was conducted framework of CORDIOPREV study, clinical trial which involved 837 165 CHD. We contrasted our findings reference 375 individuals (270 men, 105 women) without CVD....
Type 2 diabetes mellitus (T2DM) is currently a major global public health problem. Although disease remission possible, few biomarkers have been identified which can help us select the diet that best promotes remission. Our aim was to study potential of miRNAs as tool apply Mediterranean or low-fat in order achieve T2DM patients with coronary heart disease. From CORDIOPREV (n = 1002), prospective, randomized, single-blind, controlled dietary intervention trial, all newly diagnosed 190) at...
Abstract Background Telomere Length (TL), a marker of cellular aging, holds promise as biomarker to elucidate the molecular mechanism diabetes. This study aimed investigate whether shorter telomeres are associated with higher risk type 2 diabetes mellitus (T2DM) incidence in patients coronary heart disease; and determine most suitable dietary patterns, particularly Mediterranean diet or low-fat diet, can mitigate development these after follow-up period five years. Methods The CORonary Diet...
Recent evidence links diet and physical activity with type 2 diabetes mellitus (T2DM) remission, but emerging findings suggest that immune system dysregulation may play a crucial role. This study aimed to investigate the associations between neutrophils T2DM remission. We conducted comprehensive analysis of newly-diagnosed patients (N = 183) from CORDIOPREV study, without glucose-lowering treatment, were randomized follow either Mediterranean or low-fat diet. Patients classified into two...
Abstract Background and Aims Preventing new cardiovascular events in patients with established disease (CVD) is a daunting task for clinicians. Intestinal microbiota may help identify at risk, thus improving the strategies of secondary prevention. The aim this study was to evaluate baseline differences between gut from coronary heart (CHD) suffering major adverse (MACEs) following 7 years, compared CHD who did not undergo MACE period, build score associated risk MACE. Methods Within...
<ns3:p>Recent advancements in neurodegenerative research have embraced a multisystemic approach, emphasizing the role of gut microbiota and its interactions with various systems, including central nervous system. This review explores between gut-brain axis neurological illnesses associated ageing, particular focus on potential influence sex. Despite increased life expectancy, chronological ceiling human well-being remains unchanged, implying that conditions such as dementia Parkinson's...
Background/Objectives: Gut microbiota interacts with nutrients, which may be relevant to assigning a microbial signature colorectal cancer (CRC). We aim evaluate the potential of gut combined dietary habits in early detection pathological findings related CRC course screening program. Methodology: The colonoscopy performed on 152 subjects positive for fecal occult blood test showed that 6 had adenocarcinoma, 123 polyps, and 23 no findings. was analyzed by 16S metagenomic. Caret package used...
Cardiovascular disease (CVD) is more prevalent in men than women, but the mechanisms responsible for this are not fully understood. We aimed to evaluate differences trimethylamine (TMA), a microbial metabolite and its oxidized form, N-oxide (TMAO), which thought promote atherosclerosis, between women with coronary heart (CHD), using as reference non-CVD population.
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)