A5017754944- Nutritional Studies and Diet
- Diet and metabolism studies
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Nutrition and Health in Aging
- Obesity, Physical Activity, Diet
- Liver Disease Diagnosis and Treatment
- Diet, Metabolism, and Disease
- Gut microbiota and health
- COVID-19 and healthcare impacts
- Telomeres, Telomerase, and Senescence
- Cardiovascular Health and Disease Prevention
- Consumer Attitudes and Food Labeling
- Peripheral Artery Disease Management
- Atherosclerosis and Cardiovascular Diseases
- Vitamin D Research Studies
- Atrial Fibrillation Management and Outcomes
- Adipokines, Inflammation, and Metabolic Diseases
- Lipoproteins and Cardiovascular Health
- Sepsis Diagnosis and Treatment
- Blood Pressure and Hypertension Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Sirtuins and Resveratrol in Medicine
- Vitamin C and Antioxidants Research
- Health, psychology, and well-being
University of Córdoba
2016-2025
Hospital Universitario Reina Sofía
2014-2025
Instituto Maimónides de Investigación Biomédica de Córdoba
2016-2025
Instituto de Salud Carlos III
2016-2025
Centro de Investigación Biomédica en Red
2016-2024
Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition
2018-2023
University of Minnesota
2016-2017
Abstract Background Cardiovascular diseases (CVD), including coronary heart disease (CHD), display a higher prevalence in men than women. This study aims to evaluate the variations intestinal microbiota between and women afflicted with CHD delineate these against non-CVD control group for each sex. Methods Our research was conducted framework of CORDIOPREV study, clinical trial which involved 837 165 CHD. We contrasted our findings reference 375 individuals (270 men, 105 women) without CVD....
Type 2 diabetes mellitus (T2DM) is currently a major global public health problem. Although disease remission possible, few biomarkers have been identified which can help us select the diet that best promotes remission. Our aim was to study potential of miRNAs as tool apply Mediterranean or low-fat in order achieve T2DM patients with coronary heart disease. From CORDIOPREV (n = 1002), prospective, randomized, single-blind, controlled dietary intervention trial, all newly diagnosed 190) at...
Atrial fibrillation (AF) is a common cardiac arrhythmia. There growing evidence that AF risk factor for cognitive decline and dementia. In this review, we summarise epidemiological observations linking with outcomes, describe potential mechanisms explore the impact of treatments on Community-based observational studies show consistently higher rate increased dementia in persons AF. These associations are partly due to clinical stroke AF, but other mechanisms, including incidence silent...
Abstract Aims/hypothesis There is a lack of e-health systems that integrate the complex variety aspects relevant for diabetes self-management. We developed and field-tested an system (POWER2DM) integrates medical, psychological behavioural connected wearables to support patients healthcare professionals in shared decision making Methods Participants with type 1 or 2 (aged >18 years) from hospital outpatient clinics Netherlands Spain were randomised using randomisation software POWER2DM...
Several studies have supported the role of innate immune system as a key factor in sterile inflammation underlying pathophysiology atherosclerosis mice. However, its involvement humans remains unclear. This study aimed to explore association between neutrophil count, and intima-media thickness common carotid arteries (IMT-CC), well potential impact long-term dietary interventions on these associations.
Evidence suggests that enriching a diet with plant-based proteins could reduce the risk of developing type 2 diabetes mellitus. In present work, we evaluated association between change in plant protein intake (adjusted by energy) and incidence mellitus patients coronary heart disease from CORDIOPREV (coronary intervention olive oil cardiovascular prevention) study. At baseline during follow-up, underwent medical examination blood oral glucose tolerance tests. Information on patient’s dietary...
In order to evaluate whether telomere maintenance is associated with type 2 diabetes remission, newly diagnosed patients without glucose-lowering treatment (183 out of 1002) from the CORDIOPREV study (NCT00924937) were randomized consume a Mediterranean or low-fat diet. Patients classified as Responders, those who reverted during 5 years dietary intervention (
To estimate the environmental impact of a dietary intervention based on an energy-reduced Mediterranean diet (MedDiet) after one year follow-up.
- Advanced glycation end products (AGEs) play a role in kidney disease type 2 diabetes mellitus (T2DM). However, there have been no prior controlled clinical trials examining the effects of specific diets on AGE metabolism and their impact function. Our aim was to assess whether modulating resulting reduced AGEs levels, after consumption two healthy diets, could delay function decline patients with T2DM coronary heart (CHD). (540 out 1002 from CORDIOPREV study), estimated glomerular...
This study aimed to ascertain whether there is an independent association between serum magnesium (Mg) and the Carotid Intima-Media Thickness (IMT-CC), a well-accepted atherosclerotic-biomarker surrogate of cardiovascular disease (CVD), in population with high risk. Serum Mg traditional atherosclerotic risk factors were recorded 939 patients (mean age, 59.6 ± 0.3 years, 83.2% men) coronary heart (CHD) enrolled CORDIOPREV trial. strongly associated IMT-CC. Before adjusting for potential...
Abstract Background Cardiovascular disease (CVD) is the leading cause of burden in world by non-communicable diseases. Nutritional interventions promoting high-quality dietary patterns with low caloric intake value and high nutrient density (ND) could be linked to a better control CVD risk recurrence coronary disease. This study aims assess effects intervention based on MedDiet or Low-Fat over changes ND food after 1 7 years follow-up CORDIOPREV study. Methods We prospectively analyzed...
Abstract Background Peripheral artery disease (PAD) is recognized as a significant predictor of mortality and adverse cardiovascular outcomes in patients with coronary heart (CHD). In fact, coexisting PAD CHD strongly associated greater event recurrence compared either one them alone. High-density lipoprotein (HDL)-mediated cholesterol efflux capacity (CEC) found to be inversely an increased risk incident CHD. However, this association not established the context secondary prevention. sense,...
To analyse the nutritional status of patients older than 65 years included in home care program (PAD).
This work uses Compositional Data Analysis (CoDA) to examine the typical human faecal bacterial diversity in 39 healthy volunteers from Andalusian region (Spain). Stool samples were subjected high-throughput sequencing of V3 and V4 regions 16S ribosomal RNA gene using Illumina MiSeq. The numbers sequences per sample their genus-level assignment carried out Phyloseq R package. alpha indices population not influenced by volunteer’s sex (male or female), age (19–46 years), weight (48.6–99.0...