A5069207595- Synthetic Organic Chemistry Methods
- Oxidative Organic Chemistry Reactions
- Asymmetric Synthesis and Catalysis
- Catalytic C–H Functionalization Methods
- Cancer Treatment and Pharmacology
- Catalytic Cross-Coupling Reactions
- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Supramolecular Chemistry and Complexes
- Molecular Sensors and Ion Detection
- Photoreceptor and optogenetics research
- Organometallic Complex Synthesis and Catalysis
- Thermal and Kinetic Analysis
- Bioactive Natural Diterpenoids Research
- Chemical Synthesis and Reactions
- Mass Spectrometry Techniques and Applications
- Chemical Synthesis and Characterization
- Luminescence and Fluorescent Materials
- Marine Sponges and Natural Products
- Organic Chemistry Cycloaddition Reactions
- Steroid Chemistry and Biochemistry
- Advanced Synthetic Organic Chemistry
- Photochromic and Fluorescence Chemistry
- Synthesis and Properties of Aromatic Compounds
- Organoboron and organosilicon chemistry
Universidad de Huelva
2015-2022
Agence Nationale pour la Gestion des Déchets Radioactifs
1997-2020
Universidad Autónoma del Carmen
2016-2020
Centre for Sustainable Energy
2016-2020
University of British Columbia
1993-2012
Universidad Politecnica del Estado de Morelos
1996
Ottawa University
1994-1995
University of Ottawa
1994-1995
Universidad Nacional Autónoma de México
1994
Institut Charles Sadron
1991-1994
Calix[4]pyrrole phosphonate-cavitands were used as receptors for the design of supramolecular sensors creatinine and its lipophilic derivative hexylcreatinine. The sensing principle is based on indicator displacement assays an inherently fluorescent guest dye or a black-hole quencher from receptor's cavity by means competition with analytes. systems thermodynamically kinetically characterized regarding their 1:1 binding properties nuclear magnetic resonance spectroscopy (1H 31P NMR),...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTCathylation (Carbethoxylation) of Steroid AlcoholsLouis F. Fieser, Josef E. Herz, Murle W. Klohs, Miguel A. Romero, and Torlief UtneCite this: J. Am. Chem. Soc. 1952, 74, 13, 3309–3313Publication Date (Print):July 1, 1952Publication History Published online1 May 2002Published inissue 1 July 1952https://pubs.acs.org/doi/10.1021/ja01133a027https://doi.org/10.1021/ja01133a027research-articleACS PublicationsRequest reuse permissionsArticle...
The formation of host–guest complexes between seven flavylium cations and water-soluble p-sulfonatocalix[4]arene (SC4) was investigated by UV/vis absorption, fluorescence, NMR spectroscopies. results show the cationic guests form with affinities in submillimolar range. A representative chalcone/flavylium photoswitch more detail regarding its pH- light-triggered interconversion two forms. dramatic affinity differentiation SC4 binding switchable species (40 M–1 for trans-chalcone versus 3.5 ×...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTRearrangement of 6β-Bromo-Δ4-cholestene-3-one to 2α-Acetoxy-Δ4-cholestene-3-one1Louis F. Fieser and Miguel A. RomeroCite this: J. Am. Chem. Soc. 1953, 75, 19, 4716–4719Publication Date (Print):October 1, 1953Publication History Published online1 May 2002Published inissue 1 October 1953https://pubs.acs.org/doi/10.1021/ja01115a029https://doi.org/10.1021/ja01115a029research-articleACS PublicationsRequest reuse permissionsArticle...
ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTIntramolecular CuCl-Mediated Oxidative Coupling of Alkenyltrimethylstannane Functions: An Effective Method for the Construction Carbocyclic 1,3-Diene SystemsEdward Piers and Miguel A. RomeroView Author Information Department Chemistry, University British Columbia, 2036 Main Mall, Campus Vancouver, Canada V6T 1Z1 Cite this: J. Am. Chem. Soc. 1996, 118, 5, 1215–1216Publication Date (Web):February 7, 1996Publication History Received31 October...
The logically controlled and light-induced release of a tripeptide model cargo from cucurbit[8]uril host macrocycle by means photoswitch was shown in water. This provides new approach to photoresponsive selective meaningful pH window.
A general approach toward the light-induced guest release from cucurbit[7]uril by means of a photoactivatable competitor was devised. An o-nitrobenzyl-caged is photolyzed to generate competitive that can displace cargo host macrocycle solely based on considerations chemical equilibrium. With this method terpene guests inclusion complexes with demonstrated. The binding herein investigated terpenes, all being lead fragrant components in essential oils, has been characterized for first time....
A method for the phototriggered release of a biogenic amine from host-guest complex with cucurbit[7]uril macrocycle in aqueous solution was devised. The approach exploits photoinduced pH jump 8 to 5, combined pH-dependent switching competitive capacity guest dye. fluorescence fingerprint competitor can be used monitor micromolar concentration regime.
A chemically-triggered signalling cascade between cucurbituril host-guest complexes by means of multi-step competitive displacement is demonstrated. The inter-complex communication chemical information yields the release bio-relevant cargo, reminiscent cellular pathways.
Treatment of the β-trialkylstannyl α,β-unsaturated esters 1–9 with 2.5 equivalents copper(I) chloride in N,N-dimethylformamide at room temperature results efficient, stereocontrolled production highly functionalized conjugated dienes 10–18, respectively. In each these oxidative couplings, 1 equivalent product is accompanied by formation 2 both trialkylstannyl and copper metal. Keywords: alkenyltrialkylstannanes, chloride, transmetalation, dienes, coupling, esters, substituted dialkyl...
Treatment of alkyl (Z)-2,3-bis(trimethylstannyl)-2-alkenoates (7) with a catalytic amount copper(I) chloride in N,N-dimethylformamide (DMF) containing small quantity water provides very good-to-excellent yields (E)-3-trimethylstannyl-2-alkenoates (1). On the other hand, stirring solutions (Z)- or (E)-2,3-bis(trimethylstannyl)-2-alkenoates (8) DMF dilute hydrochloric acid produces, efficiently, (Z)-3-trimethylstannyl-2-alkenoates (2).
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of 6-Methyl SteroidsLuis Miramontes, Pascual Aguinaco, and Miguel A. RomeroCite this: J. Am. Chem. Soc. 1960, 82, 23, 6153–6155Publication Date (Print):December 1, 1960Publication History Published online1 May 2002Published inissue 1 December 1960https://pubs.acs.org/doi/10.1021/ja01508a045https://doi.org/10.1021/ja01508a045research-articleACS PublicationsRequest reuse permissionsArticle Views118Altmetric-Citations7LEARN ABOUT THESE...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBromination of 5α,6β-Dibromocholestane-3-oneMary Fieser, Miguel A. Romero, and Louis F. FieserCite this: J. Am. Chem. Soc. 1955, 77, 12, 3305–3307Publication Date (Print):June 1, 1955Publication History Published online1 May 2002Published inissue 1 June 1955https://pubs.acs.org/doi/10.1021/ja01617a045https://doi.org/10.1021/ja01617a045research-articleACS PublicationsRequest reuse permissionsArticle Views111Altmetric-Citations6LEARN ABOUT THESE...
ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTSynthesis of (E)- and(Z)-1-(Trimethylsilyl)-2-(siloxymethyl)-1,3-butadienes: Versatile Building Blocks for Diels-Alder Cycloadditions Including an Approach toward TaxoidsTimothy Wong, Miguel A. Romero, and Alex G. FallisCite this: J. Org. Chem. 1994, 59, 19, 5527–5529Publication Date (Print):September 1, 1994Publication History Published online1 May 2002Published inissue 1 September...
Abstract Eucalyptol, fenchyl alcohol, and geranylamine were tested for the binding to cucurbit[8]uril. Nanomolar affinities found, giving rise a highly selective of terpenes by cucurbit[8]uril when compared smaller cucurbit[7]uril. This was rationalized with better size fit larger macrocycle. These notions supported calculation packing coefficient NMR measurements free complexed terpenes. The process is mainly enthalpically driven, which associated release high‐energy water.
Simple and efficient synthetic procedures were established for the preparation of new energetic covalent compounds, salts, protonated ionic liquids based on readily available antimicrobial agent metronidazole. Some these materials exhibit desirable properties liquids, such as low vapor pressure, melting point, good chemical thermal stability, high content. For each relevant compounds prepared, stability was determined by differential scanning calorimetry. may be considered promising...