A5100774466- Food composition and properties
- Biofuel production and bioconversion
- Microbial Metabolites in Food Biotechnology
- Phytase and its Applications
- Plant tissue culture and regeneration
- Advanced biosensing and bioanalysis techniques
- Rice Cultivation and Yield Improvement
- Biosensors and Analytical Detection
- Plant Virus Research Studies
- RNA Interference and Gene Delivery
- Plant Micronutrient Interactions and Effects
- Plant Genetic and Mutation Studies
- Wheat and Barley Genetics and Pathology
- Plant Disease Resistance and Genetics
- Bacteriophages and microbial interactions
- Crop Yield and Soil Fertility
- Plant nutrient uptake and metabolism
- Enzyme Production and Characterization
- CRISPR and Genetic Engineering
- Lipid metabolism and biosynthesis
- Insect-Plant Interactions and Control
- Cancer Research and Treatments
- MicroRNA in disease regulation
- Molecular Biology Techniques and Applications
- Genetic Mapping and Diversity in Plants and Animals
Guangxi Medical University
2025
Commonwealth Scientific and Industrial Research Organisation
2013-2024
Agriculture and Food
2016-2024
Nanjing University
2024
Chinese Academy of Agricultural Sciences
2021-2024
Anhui University of Traditional Chinese Medicine
2023-2024
Qinghai University Affiliated Hospital
2024
Southern Medical University
2024
Guangdong Academy of Medical Sciences
2024
Guangdong Provincial People's Hospital
2024
Foods high in resistant starch have the potential to improve human health and lower risk of serious noninfectious diseases. RNA interference was used down-regulate two different isoforms starch-branching enzyme (SBE) II (SBEIIa SBEIIb) wheat endosperm raise its amylose content. Suppression SBEIIb expression alone had no effect on content; however, suppression both SBEIIa resulted containing >70% amylose. When grain fed rats a diet as wholemeal, several indices large-bowel function, including...
Plant Gene Register titles for PGR 99–174 to 99–187 appear below. The sequences have beendeposited in GenBank and the articles listed online through World Wide Web.To cite an electronic article as a bibliographic reference, follow stylegiven below:Park S, Thornburg RW (1998) Characterization of UMP kinase cDNAs from rice (accession nos.AF187062 AF187063) (PGR 99–174). Physiol
Analysis of barley shrunken grain mutants has identified lines with a novel high amylose starch phenotype. The causal mutation is located at the sex6 locus on chromosome 7H, suggesting synthase IIa (ssIIa) gene as candidate altered by mutation. Consistent this hypothesis, no evidence SSIIa protein expression in either granule or soluble fractions endosperm was found. Sequences gene, ssIIa, from three independent showed presence stop codon preventing translation ssIIa transcript each line....
Huntington's disease (HD) is a dominant disorder characterized by premature and progressive neurodegeneration. In order to generate an accurate model of the disease, we introduced HD-like mutation (an extended stretch 72-80 CAG repeats) into endogenous mouse Hdh gene. Analysis in vivo reveals significant levels germline instability, with expansions, contractions sex-of-origin effects evidence. Mice expressing full-length mutant protein display abnormal social behaviour absence acute Given...
IR65598-112 and the two sister lines IR65600-42 IR65600-96 are promising new plant type (NPT) rice with high yield potential. However, these susceptible to bacterial blight caused by Xanthomonas oryzae pv. (Xoo). To improve resistance of three NPT Xoo, (BB) genes, xa5, xa13, Xa21, were successfully transferred via a marker-aided backcrossing procedure. Sequence tagged site (STS) markers for genes developed based on DNA sequences their linked restriction fragment length polymorphism (RFLP)...
Raw material quality, which is influenced not only by the protein content, insoluble polymers, and glutenin-to-gliadin ratio but also starch granule size, very important for quality of bakery products. This study investigated effect high temperature drought (during grain-filling) on components yield five winter wheat varieties. Drought + heat were found to have a much greater influence than stress alone. Averaged over varieties, losses 57% after drought, 76% heat, 31% stresses. The...
The roles of starch branching enzyme (SBE, EC 2.4.1.18) IIa and SBE IIb in defining the structure amylose amylopectin barley (Hordeum vulgare) endosperm were examined. Barley lines with low expression or IIb, both isoforms generated through RNA-mediated silencing technology. These enabled study role each these determining content, distribution chain lengths, frequency amylopectin. In where reduced by >80%, a high phenotype (>70%) was observed, while reduction either alone had minor impact on...
Drinking alcohol has a long tradition in Chinese culture. However, data on the prevalence and patterns of consumption China, its main correlates, are limited.During 2004-08 China Kadoorie Biobank recruited 512,891 men women aged 30-79 years from 10 urban rural areas China. Detailed information was collected using standardized questionnaire, related to socio-demographic, physical behavioural characteristics separately.Overall, 76% 36% reported drinking some during past 12 months, with 33% 2%...
Abstract Background The transitions from juvenile to adult and reproductive phases of growth are important stages in the life cycle plants. regulators these include miRNAs, particular miR156 miR172 which part a regulatory module conserved across angiosperms. In Arabidopsis miR171 represses differentiation axillary meristems by repressing expression SCARECROW-LIKE(SCL) transcription factors, however role has not been examined other Results To investigate roles mir171 its target genes monocot,...
Summary Resistant starch ( RS ), a type of dietary fibre, plays an important role in human health; however, the content most modern processed starchy foods is low. Cereal starch, when structurally manipulated through modified biosynthetic pathway to greatly increase amylose content, could be food source . Transgenic studies have previously revealed requirement simultaneous down‐regulation two branching enzyme SBE ) II isoforms both located on long arm chromosome 2, namely SBEII and b ,...
•HER2DX assay is highly reproducible and robust intra- inter-laboratories.•HER2DX proved performance for different protocol variations including platforms.•HER2DX has proven technical reliability in predicting outcomes early-stage HER2-positive breast cancer. BackgroundHER2DX, a multianalyte genomic test, been clinically validated to predict cancer recurrence risk (relapse score), the probability of achieving pathological complete response post-neoadjuvant therapy (pCR likelihood individual...
A genetic response of Escherichia coli to nitric oxide or superoxide-generating agents such as paraquat is controlled by the soxRS locus. The intracellular redox signals generated these are sensed SoxR protein which, when activated, functions a potent activator soxS transcription. resulting increased level SoxS then activates approximately 10 genes that constitute regulon. Although homologous COOH-terminal region AraC family regulatory proteins, mechanism which regulon promoters unknown. We...
Abstract Chlamydomonas reinhardtii displays a diurnal rhythm of starch content that peaks in the middle night phase if algae are provided with acetate and CO2 as carbon source. We show this is controlled by circadian clock tightly correlated to ADP-glucose pyrophosphorylase activity. Persistence depends on presence either soluble synthase III or granule-bound I (GBSSI). both enzymes play similar function synthesizing long glucan fraction interconnects amylopectin clusters. demonstrate log...
Abstract Background During the early stages of seed development many genes are under dynamic regulation to ensure proper differentiation and establishment tissue that will constitute mature grain. To investigate how miRNA contributes this process in barley, a combination small RNA mRNA degradome analyses were used identify miRNAs their targets. Results Our analysis identified 84 known 7 new together with 96 putative target regulated through slicing mechanism grain tissues during first 15...
Potato tuber is a high yielding food crop known for its levels of starch accumulation but only negligible triacylglycerol (TAG). In this study, we evaluated the potential lipid production in potato tubers by simultaneously introducing three transgenes, including WRINKLED 1 (WRI1), DIACYLGLYCEROL ACYLTRANSFERASE (DGAT1) and OLEOSIN under transcriptional control tuber-specific (patatin) constitutive (CaMV-35S) promoters. This coordinated metabolic engineering approach resulted over 100-fold...
Congenital anomalies of the kidney and urinary tract (CAKUTs) are some most common birth defects affecting newborns. CAKUTs often have poor outcomes owing to limited experience physicians in developing countries regarding antenatal postnatal diagnosis. We aimed estimate epidemiology using data from a hospital-based registry Zhejiang Province, China. included total 2790 newborns with CAKUTs, identified among 1,748,038 births during 2010–2016. The prevalence type maternal neonatal...