A5075223473- Intracerebral and Subarachnoid Hemorrhage Research
- Acute Ischemic Stroke Management
- Cerebrovascular and genetic disorders
- Alzheimer's disease research and treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Amyloidosis: Diagnosis, Treatment, Outcomes
- COVID-19 Clinical Research Studies
- Alcoholism and Thiamine Deficiency
- Multiple Sclerosis Research Studies
- Tracheal and airway disorders
- Long-Term Effects of COVID-19
- Thyroid and Parathyroid Surgery
- Medical Imaging and Pathology Studies
- Cerebrovascular and Carotid Artery Diseases
- Neurology and Historical Studies
- Neurological Disorders and Treatments
- Dementia and Cognitive Impairment Research
- Intracranial Aneurysms: Treatment and Complications
University College London
2024-2025
Bogomolets National Medical University
2023-2025
National Hospital for Neurology and Neurosurgery
2024-2025
MRC Prion Unit
2024
University College London Hospitals NHS Foundation Trust
2024
Medical University of Graz
2024
University of Bern
2024
University Hospital of Bern
2024
Transient focal neurological episodes (TFNE), often associated with convexity subarachnoid hemorrhage (cSAH), are common in cerebral amyloid angiopathy (CAA), but their pathophysiology remains incompletely understood. In six patients unremitting TFNE, using high‐resolution post‐contrast magnetic resonance imaging and vessel wall (VWI), we found various combinations of transient leptomeningeal, parenchymal enhancement; 5 6 the enhancement included regions corresponding anatomically to...
Abstract Background and purpose An increasing number of cases iatrogenic cerebral amyloid angiopathy (CAA) have now been reported worldwide. Proposed diagnostic criteria require a history medical intervention with potential for amyloid‐β transmission, example those using cadaveric dura mater or requiring instrumentation the brain spinal cord. Clinical presentation occurs after an appropriate latency (usually three four decades); to date, most patients CAA had ‘early‐onset’ disease (compared...
Cerebral amyloid angiopathy (CAA)-associated lobar intracerebral hemorrhage (ICH) has a high risk of recurrence, but the underlying mechanisms remain uncertain. We, therefore, aimed to characterize patterns recurrent ICH.
Background We aimed to describe neuroimaging features, clinical profiles and long-term outcomes in patients with iatrogenic cerebral amyloid angiopathy (iCAA). Methods performed a systematic literature search for case series of iCAA included individual their longitudinal data this pooled cohort study. Patients meeting modified version the Queen Square criteria were included. Baseline follow-up MRIs centrally analysed markers CAA using validated rating scales. Results 51 (68.6% male, median...
Although most spontaneous intracerebral hemorrhages (ICHs) are due to cerebral small vessel diseases (SVDs), between 1 in 7 and 10 a macrovascular cause. Rapid diagnosis has important therapeutic prognostic implications but sometimes requires digital subtraction angiography (DSA), an invasive procedure which cannot be performed all patients. MRI provides optimal sensitivity for markers of SVD was not included previous risk stratification scores. We aimed create validate score causes ICH...
Cerebral amyloid angiopathy-related inflammation (CAA-ri) is a subtype of CAA with distinct clinical and radiologic features. Existing diagnostic criteria require the presence characteristic asymmetrical white matter hyperintensity (WMH), together classical hemorrhagic neuroimaging markers CAA. There are limited data for other CAA-ri. This case series from specialist hospital intracerebral hemorrhage service. We describe 4 patients CAA-ri who had regions sulcal hyperintensity, or without...
Objective — to study the effect of leukoaraiosis (LA) severity on functional recovery patients with atherothrombotic ischemic stroke (IS) 90 days after onset disease.Methods and subjects. We performed a cohort prospective 82 acute IS. 37 men 45 women (mean age 71.1 ± 9.4 years) were examined. The inclusion criteria first IS, variant (according TOAST criteria), hospitalization outside «therapeutic window». degree impairment neurological functions was assessed by NIHSS scale, estimated using...
Calcification of basal ganglia is a radiological finding that often secondary to variety conditions or physiological aging the brain. According literature data, its frequency varies greatly due lack modern large‑scale population studies prevalence calcification, as well significant population. Clinical manifestations calcification are variable. Patterns neuroimaging findings also differ in clinical case descriptions.Idiopathic (Fahr’s disease) disease, caused by mutations certain genes, has...
Wernicke encephalopathy (WE), is an emergency acute neuropsychiatric condition, which develops secondary to thiamine deficiency. According data of multiple investigations, this disorder greatly underdiagnosed. WE classically connected chronic alcohol abuse, but also diagnosed in non‑alcoholic patients with different risk factors including severe vomiting, malnutrition, systemic infections, malignancies, chemotherapy, HIV/AIDS, gastrointestinal surgeries or disease, and renal problems. We...