A5009217752- Cerebral Venous Sinus Thrombosis
- Venous Thromboembolism Diagnosis and Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Acute Ischemic Stroke Management
- Biomedical Research and Pathophysiology
- Blood Coagulation and Thrombosis Mechanisms
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Atrial Fibrillation Management and Outcomes
- Liver Diseases and Immunity
- Aortic Disease and Treatment Approaches
- Hepatitis C virus research
- Liver Disease Diagnosis and Treatment
- Neurosurgical Procedures and Complications
- Moyamoya disease diagnosis and treatment
- Biomedical and Engineering Education
- Artificial Intelligence in Healthcare and Education
- Polyomavirus and related diseases
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Multiple Sclerosis Research Studies
- Pediatric Urology and Nephrology Studies
- Radiomics and Machine Learning in Medical Imaging
- Cardiac tumors and thrombi
- Diabetes and associated disorders
- Transplantation: Methods and Outcomes
- Cerebrospinal fluid and hydrocephalus
Assuta Medical Center
2023-2025
National Hospital for Neurology and Neurosurgery
2024
University College London
2024
Medical University of Graz
2024
MRC Prion Unit
2024
University of Bern
2024
University Hospital of Bern
2024
Rabin Medical Center
2018-2023
University at Buffalo, State University of New York
2023
Tel Aviv University
2019-2022
Cerebral amyloid angiopathy (CAA)-associated lobar intracerebral hemorrhage (ICH) has a high risk of recurrence, but the underlying mechanisms remain uncertain. We, therefore, aimed to characterize patterns recurrent ICH.
Importance One of 10 patients develop epilepsy in the late phase after cerebral venous thrombosis (CVT) diagnosis but predicting individual risk is difficult. Objective To and externally validate a prognostic score to estimate post-CVT epilepsy. Design, Setting, Participants This observational cohort study included both retrospective prospective enrolled from 1994 through 2022. For development DIAS 3 score, data International CVT Consortium (n = 1128), large international hospital-based...
Abstract Background Artificial Intelligence (AI) is increasingly used to assess Ulcerative Colitis (UC) disease activity in clinical trials, with the goal of matching or exceeding expert performance a reproducible manner. Certai has been created from previous AI work as model that conforms new definitions within Modified Mayo Endoscopic Score criteria. Methods Using self-supervised DINOv2 method, was pre-trained on 845 colonoscopic procedures and then refined annotations proprietary Software...
Background: Acute symptomatic seizures (ASYS) is a common presentation in cerebral sinus venous thrombosis (CSVT) patients. Objectives: We aimed to characterize CSVT patients experiencing ASYS within 7 days from presentation. Additionaly, we find predictors for Methods: Prospective databases six academic centers (January 2010–December 2023) were retrospectively analyzed. Clinical outcomes at the 90-day follow-up included seizure occurrence and modified-Rankin-Scale (mRS). Results: From 529...
Introduction: Embolic stroke of undetermined source (ESUS) is a common medical challenge regarding secondary prevention strategy. Cardiac imaging the cornerstone embolic workup, in an effort to diagnose high risk cardio-embolic sources. computed tomography angiography (CCTA) emerging modality with diagnostic performance for intra-cardiac thrombus detection. The yield CCTA implementation addition standard care ESUS workup unknown. Thus, aim this study was assess utility detecting thrombi...
Although most spontaneous intracerebral hemorrhages (ICHs) are due to cerebral small vessel diseases (SVDs), between 1 in 7 and 10 a macrovascular cause. Rapid diagnosis has important therapeutic prognostic implications but sometimes requires digital subtraction angiography (DSA), an invasive procedure which cannot be performed all patients. MRI provides optimal sensitivity for markers of SVD was not included previous risk stratification scores. We aimed create validate score causes ICH...
Background Information regarding the safety and efficacy of specific direct oral anticoagulants (DOAC) in treatment cerebral sinus venous thrombosis (CSVT) is scarce. Apixaban one most frequently prescribed DOACs. Therefore, we aimed to compare with those vitamin k antagonists (VKA) patients CSVT. Methods Prospective CSVT databases from seven academic medical centers were retrospectively analyzed. Patients treated compared VKA. Data on demographics, clinical presentations, risk factors,...
Objectives. Cerebral sinus venous thrombosis (CSVT) is a rare stroke subtype and data regarding prognostic factors to predict outcomes are lacking. Thus, we aimed identify predictors for outcome among CSVT patients. Materials Methods. Prospective databases from four academic medical centers were retrospectively studied. Demographics, clinical presentations, risk factors, radiological, parameters compared. Results. Out of 508 patients diagnosed with CSVT, 21 (4%) died, 91 (18.6%) had...
<h3>Objective</h3> MS is a demyelinating CNS disorder with spectrum of clinical patterns regarding course and prognosis. Although several prognostic factors are considered in the initial evaluation patients, biological markers defining disease guiding treatments currently lacking. It unknown whether patients CSF pleocytosis differ regard to symptoms, course, prognosis from those without. The aim this study was evaluate during presentation has an impact on progression MS. <h3>Methods</h3> We...
Cerebral sinus venous thrombosis (CSVT) is a rare neurovascular entity, usually associated with acquired or genetic hypercoagulable states. In up to 30% of the cases it remains idiopathic. Bone marrow proliferation disorders that are Janus Kinase 2 V617F mutation (JAK-2) known causes systemic and cerebral thrombosis-at times despite normal blood counts-for which hematologic treatment exists. However, JAK-2 prevalence in CSVT not clear.In this retrospective analysis, data 236 patients...
Background: Detection of subclinical rejections has been a real challenge for pediatric nephrology. We hypothesized that donor-derived cell-free DNA (dd-cfDNA) in combination with serum creatinine levels and kidney biopsy provide “gold-standard” clinicians so treatment rejection can be initiated appropriately. Design/Methods: performed two-year cohort study on total (n=5) patients aged 5-19 years who received transplant within 2015-2019. Blood was collected dd-cfDNA, i.e., AlloSure, at the...
Cerebral sinus vein thrombosis (CVT) is a relatively rare neurovascular entity, usually associated with acquired or genetic hypercoagulable states, and in many cases it remains idiopathic. Trauma also CVT among patients major head neck trauma, including penetrating injuries. However, acceleration trauma has only been described few so far. We present an unusual case of 19-year-old woman no past medical history, admitted extensive following sneezing. A thorough investigation did not reveal any...
Spinal cord infarction (SCI) is a rare neurovascular disorder often presented with acute spinal syndrome. The diagnosis generally made clinically, appropriate neuroimaging to confirm the and exclude other causes. We present an unusual case of 48-year-old woman no relevant past medical history, admitted paraparesis infarct on magnetic resonance imaging. A thorough investigation revealed asymptomatic unknown heart failure secondary hypertrophic cardiomyopathy, suggestive cardioembolic...
Aims: Late treatment failure in chronic hepatitis C (CHC), defined as relapse during follow-up after an end-of-treatment response, occurs up to 30% of patients treated with a standard combination therapy pegylated IFN-alfa and ribavirin (Caliceti P, Dig Liver Dis 2004; 36, Suppl. 3: 334–339). Thus far, only hcv-genotype, age, dose duration infection have been proposed predictors relapse. We sought identify other potential genotype-1 who received weight-based PegIFN-alfa-2b within large...
Aims: A virological response to pegylated IFN and ribavirin is typically associated with a prompt decline in serum transaminases. The course of ALT normalization treated patients cHC has been observed within German nationwide surveillance study compared achievement HCV-RNA-negativity the same cohort.
Background: Ischemic stroke (IS) admissions in patients with atrial fibrillation (AF) using either direct oral anticoagulants (DOAC) or Vitamin K antagonists (VKA) are commonly seen units but data on their prevalence and causes scarce. Understanding the frequency/causes of failures current FDA-approved preventive methods AF is important to reduce risk related death/disability. Methods: The Neuro-AFib study a multicenter effort geared toward elucidating consequences IS hemorrhagic...