Domagoj Ivastinović

ORCID: 0000-0002-7352-4820
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About
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Research Areas
  • Retinal and Macular Surgery
  • Intraocular Surgery and Lenses
  • Retinal Diseases and Treatments
  • Glaucoma and retinal disorders
  • Neuroscience and Neural Engineering
  • Retinal and Optic Conditions
  • EEG and Brain-Computer Interfaces
  • Retinal Imaging and Analysis
  • Retinal Development and Disorders
  • Ophthalmology and Visual Impairment Studies
  • Vascular Malformations Diagnosis and Treatment
  • Photoreceptor and optogenetics research
  • Corneal surgery and disorders
  • Tactile and Sensory Interactions
  • Clinical practice guidelines implementation
  • Gaze Tracking and Assistive Technology
  • Advanced Memory and Neural Computing
  • Facial Trauma and Fracture Management
  • Ophthalmology and Visual Health Research
  • Traumatic Ocular and Foreign Body Injuries
  • Ocular Surface and Contact Lens
  • Ocular Infections and Treatments
  • Prion Diseases and Protein Misfolding
  • Health Literacy and Information Accessibility
  • Proteoglycans and glycosaminoglycans research

Medical University of Graz
2015-2024

University of Rijeka
2024

University of Graz
2009-2019

Purpose Retinal detachment (RD) is one of the most frequently diagnosed ophthalmologic conditions requiring prompt surgical intervention. Combination proper technique and new diagnostic markers, both clinical molecular, can help improve diagnosis prognosis RD treatment. Methods 12 patients with rhegmatogenous (rRD) were included into study after obtaining patient consent Regional Ethical Approval (average age: 58.1 ± 17.4 years). OCT was performed before 23G vitrectomy for RD. Pure...

10.1371/journal.pone.0217548 article EN cc-by PLoS ONE 2019-06-11

Purpose To assess the association between vitreous hyper-reflective dots (VHD) and macular thickness changes following uneventful phacoemulsification. Methods In this prospective cohort study optical coherence tomography (OCT) examinations were performed preoperatively 1 week, month 3 months postoperatively in patients undergoing cataract surgery. OCT images analyzed for retinal central subfield (CST) preretinal VHDs. Surgeries recorded assessment of lens fragments space Berger. Results 111...

10.1371/journal.pone.0300148 article EN cc-by PLoS ONE 2024-04-09

Background/Aims Neurofilament light chain (NfL) levels in cerebrospinal fluid and serum are reliable indicators for neuroaxonal damage a broad spectrum of neurodegenerative diseases. Herein, we investigate NfL anterior chamber patients with glaucoma. Methods Patients scheduled routine glaucoma or cataract surgery were recruited this study. Retinal nerve fibre layer thickness was measured by optical coherence tomography (OCT, Heidelberg Spectralis). analysed Simoa SR-X Analyzer (Quanterix;...

10.1136/bjo-2021-320828 article EN British Journal of Ophthalmology 2022-06-24

To evaluate the impact of oxidative stress - present in glaucoma on vitreous. We therefore compare presence early and late stages posterior vitreous detachment (PVD) between patients with controls.The state was evaluated by combination optical coherence tomography ultrasound. The main outcome classified into 'no PVD', 'initial PVD' 'advanced PVD'.We 48 (age: mean 66.5 ± 11.9 years; visual field deviation: 10.4 6.8 dB) compared results 101 previously investigated controls 73.6 9.3 years)....

10.1111/aos.13339 article EN Acta Ophthalmologica 2016-12-14

Periodontitis and diabetes are known to have a bidirectional relationship. Diabetic macular edema is complication of that strongly influenced by inflammatory pathways. However, it remains be established whether inflammation at other locations, such as periodontitis, affects diabetic edema. Here, we investigated the prevalence periodontitis in patients treated for edema.Patients with were recruited this cross-sectional study Medical University Graz. Macular was documented optical coherence...

10.1007/s00784-021-04028-x article EN cc-by Clinical Oral Investigations 2021-06-22

The study investigates the utility of a newly designed mobility test for repeated testing visual function in patients with severe impairment and future application evaluating functional progress artificial vision. Ten subjects divided into three groups based on acuity (VA) ranging from light perception to 20/200 reduced field (VF) were included study. consisted using set four different but structurally similar relatively short mazes having constant number obstacles various sizes. subjects,...

10.1088/1741-2560/4/1/s12 article EN Journal of Neural Engineering 2007-02-26

To investigate the early and late stages of posterior vitreous detachment (PVD) in foveal area correlation with age gender.Three hundred thirty-five emmetropic eyes 271 Caucasian patients (216 women/119 men) were examined by optical coherence tomography (OCT) ultrasound (US). Eyes classified into groups according to (up 69.9; 70-74.9; 75-79.9; over 80 years) clinical findings [Vitreous state: Detached US; OCT; Foveal adhesion (FA); Attached vitreous].The mean was 76 ± 8 ranging from 44 89...

10.1111/j.1755-3768.2011.02310.x article EN Acta Ophthalmologica 2011-11-22

To report on radiation-related side effects and complications after ruthenium-106 plaque brachytherapy of uveal melanomas.Medical records 143 eyes with melanoma, treated by between 1997 2012 at a single center, were analyzed. We evaluated the occurrence anterior posterior segment eye. The influence patient, tumor treatment parameters outcome was analyzed multivariate time to event analysis considering competing risks.The median overall follow-up 37.9 months. After treatment, estimated risk...

10.1371/journal.pone.0183833 article EN cc-by PLoS ONE 2017-08-31

To evaluate the relevance of external limiting membrane (ELM) on visual and morphological results in eyes with diabetic macular edema (DME) that underwent pars plana vitrectomy (PPV) epiretinal (ERM) internal (ILM) peeling.Medical records patients DME who PPV at our unit between January 2017 December 2019 were reviewed. We assessed preoperative postoperative best-corrected acuity (BCVA), central thickness (CMT) using spectral domain OCT (optical coherence tomography). Exclusion criteria...

10.1186/s12886-021-02095-y article EN cc-by BMC Ophthalmology 2021-09-15

Glaucoma has a significant impact on quality of life. Here, we aimed to evaluate the influence reduction in glaucoma medications life and patient satisfaction after phacoemulsification combined with Xen gel stent. We carried out cross-sectional survey patients who underwent stent at Medical University Graz, Austria. Quality was assessed using German version Symptoms Scale (GSS)—questionnaire. Patients were also asked whether operation reduced indicate their overall from 1 (totally...

10.3390/jcm11123450 article EN Journal of Clinical Medicine 2022-06-15

Abstract Purpose Numerous studies suggest that reactive oxygen species play a crucial role in the development of glaucoma. Since glaucoma patients exhibit posterior vitreous detachment earlier than controls, it has been suggested species—increased glaucoma—also affect vitreous. In present study we evaluated influence open-angle oxidative stress on redox state albumin. Methods Albumin states and plasma were 22 subjects—11 11 controls—matched for age, gender, state. According to cysteine-34,...

10.1007/s10792-019-01268-5 article EN cc-by International Ophthalmology 2020-01-11

Abstract Purpose To derive a Delphi method‐based consensus for the surgical management of Full Thickness Macular Hole (FTMH) and Lamellar (LMH). Methods 37 expert VR surgeons from 21 mainly European countries participated in questionnaire diagnosis treatment FTMHs LMHs. Results A total 36 items were rated round 1 by participants, which 10 achieved consensus: intraoperative verification PVD; clinical superiority OCT‐based FTMH classification; practical ineffectiveness ocriplasmin; circular...

10.1111/aos.15682 article EN Acta Ophthalmologica 2023-05-10

Abstract Purpose To report on the first 4 months experience of a patient with active IRIS‐ Implant. Methods weeks after implantation training implant started. Thresholds were measured at each day. Light perception, light localisation, point to discrimination and motion detection special test procedures. Visual function was performed. Results perception achieved, when stimuli generated by computer camera mode. All tests successful. Conclusion Successful stimulation major improvements during...

10.1111/j.1755-3768.2009.3115.x article EN Acta Ophthalmologica 2009-09-01

As part of a clinical trial, an investigational epiretinal implant (IMI Intelligent Medical Implant) was implanted in retinitis pigmentosa patient. The prosthesis wirelessly controlled by visual interface containing microcamera, providing wireless data and energy transmission. Forty-nine (49) electrodes were used for pattern recognition. This study examined the changes perceptual thresholds over time its relation to long-term stimulation. goal introduce stimulus-related depression threshold...

10.1111/aos.12179 article EN Acta Ophthalmologica 2013-09-25

This study uses a list of 17 predefined questions to examine the information on rhegmatogenous retinal detachment available patients via 6 public websites.

10.1001/jamaophthalmol.2018.4682 article EN JAMA Ophthalmology 2018-10-05

Do gender, age, body mass and height influence eye biometrical properties in young adults?A total of 155 eyes (92 female, 63 male) healthy subjects between the ages 18 39 years were included study. The subjects' gender age recorded, their mass, measured.The male had significantly thicker flatter corneas lower minimal rim-to-disk ratios than female did. In both genders, showed strong, negative correlations with anterior chamber depth pupil diameter a positive correlation lens thickness. We...

10.3390/ijerph182111719 article EN International Journal of Environmental Research and Public Health 2021-11-08

To evaluate vitrectomy in conjunction with the use of perfluorocarbon, cerclage, laser retinopexy, lens removal and silicone oil as surgical treatment proliferative vitreoretinopathy associated retinal detachment.Sixty-two eyes 62 patients were treated for complicated detachment following failed prior scleral buckling. Outcome measures were; reattachment rate 6 months after removal, status retina, visual acuity (VA), duration tamponade frequency reoperations.The final was 95%. Reoperations...

10.1111/j.1755-3768.2009.01763.x article EN Acta Ophthalmologica 2010-02-12

Ascorbic acid is present at high concentrations in the vitreous and plays a central role redox chemistry. Albumin main protein with antioxidant properties occurs different oxidation states, which can be used as indicators, but have not been studied vitreous. This study, therefore, addressed state of cysteine-34 albumin relation to ascorbic content, has suggested exert function detoxifying reactive oxygen A total 58 samples obtained from patients undergoing vitrectomy were analyzed for (i)...

10.1016/j.freeradbiomed.2019.11.008 article EN cc-by-nc-nd Free Radical Biology and Medicine 2019-11-06

To assess the rate of pseudophakic cystoid macular edema (pCME) in uneventful cataract surgery surgeons training vs experienced and to analyze pCME according surgeon's sex.Medical reports post phacoemulsification between 2010 2018 at Department Ophthalmology, Medical University Graz, Austria, were reviewed for pCME. A running lifetime number preceding surgeries was used express hands-on experience. cut-off 300 defined distinguish surgeons. Outcome parameters incidence pCME, patient's sex...

10.1371/journal.pone.0279518 article EN cc-by PLoS ONE 2022-12-27
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