A5102754716- Ocular Surface and Contact Lens
- Allergic Rhinitis and Sensitization
- Glaucoma and retinal disorders
- Salivary Gland Disorders and Functions
- Corneal surgery and disorders
- Nasolacrimal Duct Obstruction Treatments
- Dermatology and Skin Diseases
- Corneal Surgery and Treatments
- Urticaria and Related Conditions
- Retinal and Optic Conditions
- Ophthalmology and Eye Disorders
- Acne and Rosacea Treatments and Effects
- Psoriasis: Treatment and Pathogenesis
- Dermatologic Treatments and Research
- Sympathectomy and Hyperhidrosis Treatments
- Multiple Myeloma Research and Treatments
- Salivary Gland Tumors Diagnosis and Treatment
- Ubiquitin and proteasome pathways
- Ergonomics and Musculoskeletal Disorders
- Intraoperative Neuromonitoring and Anesthetic Effects
- Cerebral Venous Sinus Thrombosis
- Ocular Infections and Treatments
- Advanced Drug Delivery Systems
- Protein Degradation and Inhibitors
- Exercise and Physiological Responses
Medical University of Graz
2014-2025
University of Graz
2009-2021
Graz University Hospital
2000-2003
To assess subjective symptoms, tear function factors, and ocular surface morphology in the clinical course of patients with dry eye syndrome under treatment within an observation period up to 8 years.In 97 (78 women 19 men) discomfort, a diagnosis was made based on typical symptoms reduced film breakup time less than 10 seconds. Subsequent evaluations revealed aqueous deficiency 9 patients, meibomian gland dysfunction 32 combined 30 associated Sjögren 12 14 patients. Follow-up assessments...
Abstract Purpose The purpose of this study was to assess the prevalence meibomian gland dysfunction ( MGD ) and its association with tear film ocular surface parameters in an Austrian clinical population dry eye patients. Methods records 1372 consecutive patients from a unit were analysed retrospectively. Symptoms objective evaluated. Patients classified into pure , aqueous deficiency ATD ), combined anterior blepharitis AB Sjogren's syndrome SS without together . Results Nine‐hundred...
To retrospectively describe the performance of topical insulin in persistent corneal epithelial defects (CED) and ulcers. We reviewed cases patients treated for CED ulcers using a concentration 25 IU per milliliter three times day. The closure rate was main outcome measure. Thirty-seven episodes 29 with were reviewed. There wide range additionally used medication, underlying pathologies as well ocular systemic comorbidities our cohort. On average, drops started after 36 days conventional...
Our study aimed to investigate the prevalence and timing of ocular surface manifestations in hospitalized COVID-19 patients, providing insights into occurrence eye involvement before, during, or after illness. This contributes understanding extent COVID-19, which has been suggested occur due potential viral entry through eyes. 451 confirmed patients had a history hospitalization Styria, Austria. The included 176 aged 18-95 years who tested positive for SARS-CoV-2 nasopharyngeal swabs by...
ObjectiveTo elucidate the pathogenesis of dupilumab [Dupixent®]-associated ocular surface disease (DAOSD).DesignProspective single-centre cohort study.Subjects and ControlsTwenty patients with moderate to severe atopic dermatitis (AD) who received ten age- sex-matched healthy controls were enrolled in study.MethodsThe study underwent a thorough slit lamp whole-body dermatologic examination. Conjunctival swabs smears collected at baseline, four sixteen weeks after treatment initiation, during...
This report illustrates the case of a female patient suffering from severe ocular discomfort, tinnitus and ageusia, 7 months after SARS-CoV-2 infection. The medical history implicated diagnosis LONG-COVID with pain as most debilitating symptom. In-vivo confocal microscopy revealed corneal microneuromas hyperreflectivity irregular enlargement nerve endings in both eyes, which led to neuropathic pain. aim this is increase awareness that COVID-19 induced can also occur cornea representing human...
Background/Aims Neurofilament light chain (NfL) levels in cerebrospinal fluid and serum are reliable indicators for neuroaxonal damage a broad spectrum of neurodegenerative diseases. Herein, we investigate NfL anterior chamber patients with glaucoma. Methods Patients scheduled routine glaucoma or cataract surgery were recruited this study. Retinal nerve fibre layer thickness was measured by optical coherence tomography (OCT, Heidelberg Spectralis). analysed Simoa SR-X Analyzer (Quanterix;...
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To evaluate the long-term prevalence of canaliculitis associated with use SmartPlugs.This retrospective study included 42 eyes 25 dry eye patients at our institution who received a SmartPlug insertion between 2004 and 2008. Irrigation lacrimal system was performed in all prior to ensure patency system. The median follow-up time 7.9 (5.6-10.5) years after plug insertion.Six (seven eyes) (42 developed canaliculitis. per patient 24%, 16.6%. from onset 4.7 (1.4-6.0) years. age affected 61.5...
Abstract Purpose Lubricant eye drops are the main therapeutic resource for dry disease (DED), with each drop representing equivalent of ocular surface treatment. Thus, any reduction in frequency application reflects a degree success. Considering also socioeconomic burden DED, we investigated (DF) as parameter to potentially track success therapy severe DED. Hyaluronan (HA)‐containing have become first choice tear substitution many countries, and recent data indicate that average molecular...
Aim: To compare collared silicone punctal plugs to intracanalicular SmartPlugs for the treatment of moderate severe dry eye.Materials and methods: In this prospective, randomized, single blind, clinical study, 30 patients (60 eyes) who had been diagnosed with eye syndrome were enrolled. Study group I (n = received II SmartPlugs. Data Schirmer test, tear break-up time, vital staining, subjective symptoms frequency artificial application recorded at baseline 3 months after occlusion.Results:...
The purpose of this study was to investigate the effect high molecular weight hyaluronan (HMWHA) eye drops on subbasal corneal nerves in patients suffering from severe dry disease (DED) and evaluate damage associated with DED. Designed as an international, multicenter study, 16 symptoms at least Ocular Surface Disease Index (OSDI) score 33, fluorescein staining (CFS) Oxford grade 3, were included randomized into two arms. control group continued use their individual optimum artificial tears...
Introduction/Objectives: The patient perspective is an essential outcome parameter in the quest for effective therapy primary Sjögren's Syndrome (PSS). EULAR Patient Reported Index (ESSPRI) recommended by to quantify patient's symptom burden and has been used several clinical trials. Surprisingly, perception of dryness quantified with ESSPRI does not correlate objective measures salivary or lacrimal flow. Thus, we evaluated a newly developed assessment tool-the Primary Quality Life...
Purpose: Hazelnut and birch pollen are known to destroy tear film components attack ocular surface cells. We investigated further species from different plant families, whether they show similar effects on human fluid an epithelial cell line in vitro, provide a broad basis for research reactions affecting the surface.Materials methods: Regional families (Adoxaceae, Betulaceae, Fagaceae, Juglandaceae, Malvaceae, Oleaceae, Pinaceae, Plantaginaceae, Poaceae, Salicaceae, Sapindaceae) were...
We investigated the effects of a visual picking system on ocular comfort, surface and tear function compared to those voice guided solution.Prospective, observational, cohort study.Institutional.A total 25 young asymptomatic volunteers performed commissioning over 10 hours two consecutive days.The operators were in process by different solutions, either visually or while their subjective symptoms parameters recorded.The analogue scale (VAS) values, according dry eye symptoms, condition...