A5053201715- Dermatology and Skin Diseases
- Cutaneous lymphoproliferative disorders research
- Ocular Surface and Contact Lens
- Medical and Biological Ozone Research
- Allergic Rhinitis and Sensitization
- Advancements in Transdermal Drug Delivery
- Skin Protection and Aging
- Antimicrobial Peptides and Activities
- Asthma and respiratory diseases
- Advanced Fiber Optic Sensors
- Psoriasis: Treatment and Pathogenesis
- Proteins in Food Systems
- Polydiacetylene-based materials and applications
- Immunotherapy and Immune Responses
- Light effects on plants
- Nanoplatforms for cancer theranostics
- Probiotics and Fermented Foods
- Nail Diseases and Treatments
- CAR-T cell therapy research
- Food Allergy and Anaphylaxis Research
- Photodynamic Therapy Research Studies
- Chemical Reactions and Isotopes
- Fungal Infections and Studies
Medical University of Graz
2021-2024
Freie Universität Berlin
2020-2022
Humboldt-Universität zu Berlin
2022
Charité - Universitätsmedizin Berlin
2022
Atopic dermatitis (AD) is a common chronic inflammatory skin disease that significantly affects the patient’s quality of life. A disrupted barrier, type 2 cytokine-dominated inflammation, and microbial dysbiosis with increased Staphylococcus aureus colonization are critical components AD pathogenesis. Patients exhibit decreased expression antimicrobial peptides (AMPs) which linked to by . The microbiome itself source several AMPs. These host- microbiome-derived AMPs define landscape based on...
ObjectiveTo elucidate the pathogenesis of dupilumab [Dupixent®]-associated ocular surface disease (DAOSD).DesignProspective single-centre cohort study.Subjects and ControlsTwenty patients with moderate to severe atopic dermatitis (AD) who received ten age- sex-matched healthy controls were enrolled in study.MethodsThe study underwent a thorough slit lamp whole-body dermatologic examination. Conjunctival swabs smears collected at baseline, four sixteen weeks after treatment initiation, during...
Sulfoxide-functionalized nanogels show a high potential to effectively emulate the skin penetration enhancing properties of DMSO without its negative side effects.
Polymeric nanogels are promising nonirritating nanocarriers for topical delivery applications. However, conventional hydrophilic networks limit encapsulation of hydrophobic therapeutics and hinder tailored interactions with the amphiphilic skin barrier. To address these limitations, we present containing domains. Two competing factors determine favorable nanogel–skin need to be balanced through network composition: suitable surface hydrophobicity low rigidity (through physical cross-links)....
Cutaneous T-cell lymphomas (CTCL) are a group of lymphoproliferative disorders skin-homing T cells causing chronic inflammation. These cause impairment the immune environment, which leads to severe infections and/or sepsis due dysbiosis. In this study, we elucidated host-microbial interaction in CTCL that occurs during phototherapeutic treatment regime and determined whether modulation skin microbiota could beneficially affect course CTCL. EL4 lymphoma were intradermally grafted on back...
Human skin equivalents emerged as novel tools in preclinical dermatological research. It is being claimed that they may bridge the translational gap between and clinical research, yet only a few studies have investigated their suitability for drug testing so far. Therefore, we if inflammatory equivalents, which emulate hallmarks of atopic dermatitis (AD), are suitable to assess anti-inflammatory effects dexamethasone (DXM) cream formulation or loaded onto dendritic core-multishell...