- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Cardiac, Anesthesia and Surgical Outcomes
- Coronary Interventions and Diagnostics
- Cardiac Health and Mental Health
- Health Systems, Economic Evaluations, Quality of Life
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Pharmaceutical Practices and Patient Outcomes
- Cardiovascular Health and Risk Factors
- Aortic aneurysm repair treatments
- Healthcare Policy and Management
- Lipoproteins and Cardiovascular Health
- Medication Adherence and Compliance
- Diabetes Treatment and Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Primary Care and Health Outcomes
- Vascular Procedures and Complications
- Pulmonary Hypertension Research and Treatments
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Radiation Dose and Imaging
- Healthcare cost, quality, practices
- Cardiovascular Disease and Adiposity
- Clinical practice guidelines implementation
Washington University in St. Louis
2013-2022
University of Liverpool
2022
Institute of Cardiology
2021
The University of Texas Southwestern Medical Center
2013-2020
Beth Israel Deaconess Medical Center
2020
BJC HealthCare
2019
Barnes-Jewish Hospital
2014-2019
VA Eastern Colorado Health Care System
2011-2018
Cleveland Clinic
2015-2018
University of Colorado Anschutz Medical Campus
2006-2018
Little is known about cardiac adverse events among patients with nonobstructive coronary artery disease (CAD).To compare myocardial infarction (MI) and mortality rates between CAD, obstructive no apparent CAD in a national cohort.Retrospective cohort study of all US veterans undergoing elective angiography for October 2007 September 2012 the Veterans Affairs health care system. Patients prior were excluded.Angiographic extent, defined by degree (no CAD: stenosis >20%; ≥1 ≥20% but ≥70%; any...
Background— Pulmonary hypertension (PH) is associated with increased morbidity across the cardiopulmonary disease spectrum. Based primarily on expert consensus opinion, PH defined by a mean pulmonary artery pressure (mPAP) ≥25 mm Hg. Although mPAP levels below this threshold are common among populations at risk for PH, relevance of <25 Hg to clinical outcome unknown. Methods and Results— We analyzed retrospectively all US veterans undergoing right heart catheterization (2007–2012) in...
Guidelines recommend delaying noncardiac surgery in patients after coronary stent procedures for 1 year drug-eluting stents (DES) and 6 weeks bare metal (BMS). The evidence underlying these recommendations is limited conflicting.To determine risk factors adverse cardiac events undergoing following implantation.A national, retrospective cohort study of 41,989 Veterans Affairs (VA) non-VA operations occurring the 24 months a implantation between 2000 2010. Nonlinear generalized additive models...
Thermodilution (Td) and estimated oxygen uptake Fick (eFick) methods are widely used to measure cardiac output (CO). They often interchangeably make critical clinical decisions, yet few studies have compared these approaches as applied in medical practice.To assess agreement between Td eFick CO compare how well predict mortality.This investigation was a retrospective cohort study with up 1 year of follow-up. The data from the Veterans Affairs Clinical Assessment, Reporting, Tracking (VA...
Abstract Aims The prognosis of patients with MINOCA (myocardial infarction non-obstructive coronary arteries) is poorly understood. We examined major adverse cardiac events (MACE) defined as all-cause mortality, re-hospitalization for acute myocardial (AMI), heart failure (HF), or stroke 12-months post-AMI in versus AMI obstructive artery disease (MICAD). Methods and results Multicentre, observational cohort study (≥65 years) from the National Cardiovascular Data Registry CathPCI (July...
The 2013 American College of Cardiology/American Heart Association (ACC/AHA) Cholesterol Management Guideline recommends moderate-intensity to high-intensity statin therapy in eligible patients.To examine adoption the ACC/AHA guideline US cardiology practices.Among 161 practices, trends use and nonstatin lipid-lowering (LLT) were analyzed before (September 1, 2012, November 2013) after (February 2014, April 2015) publication among 4 mutually exclusive risk groups within ACC Practice...
Same-day discharge (SDD) after elective percutaneous coronary intervention (PCI) is associated with lower costs and preferred by patients. However, to our knowledge, contemporary patterns of SDD PCI respect the incidence, hospital variation, trends, costs, safety outcomes in United States are unknown.To examine (1) incidence trends SDD; (2) variation (3) association between readmissions for bleeding, acute kidney injury (AKI), myocardial infarction (AMI), or mortality at 30, 90, 365 days...
The prevalence of anemia in elective surgical patients may be as frequent 75% certain populations. A national audit demonstrated that 35% scheduled for joint replacement therapy have a hemoglobin <13 g/dL on preadmission testing. Standard practice currently consists testing 3 to 7 days before an operative procedure, precluding the opportunity effectively evaluate and manage patient with unexpected anemia. Therefore, standardized approach detection, evaluation, management preoperative setting...
Secondary prevention therapies are indicated for patients with coronary artery disease (CAD). However, nonobstructive CAD may be less likely to receive these compared obstructive CAD. Therefore, we rates of secondary medication prescription between and CAD.We conducted a retrospective cohort study 1 489 745 undergoing cardiac catheterization in 786 US centers 2004 2007. We measured aspirin, statin, β-blocker, angiotensin-converting enzyme inhibitor (ACEI)/angiotensin II receptor blocker...
Myocardial infarction (MI) patients without obstructive coronary artery disease (CAD) are at increased risk for recurrent ischemic events, but angina frequency post-MI has not been described.