- Acute Myocardial Infarction Research
- Blood Pressure and Hypertension Studies
- Medication Adherence and Compliance
- Antiplatelet Therapy and Cardiovascular Diseases
- Atrial Fibrillation Management and Outcomes
- Heart Failure Treatment and Management
- Coronary Interventions and Diagnostics
- Cardiac Health and Mental Health
- Hormonal and reproductive studies
- Emergency and Acute Care Studies
- Primary Care and Health Outcomes
- Ultrasound in Clinical Applications
- Healthcare cost, quality, practices
- Electronic Health Records Systems
- Cardiovascular Function and Risk Factors
- Health Systems, Economic Evaluations, Quality of Life
- Lipoproteins and Cardiovascular Health
- Pharmacology and Obesity Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Imaging and Diagnostics
- Cardiac Fibrosis and Remodeling
- Potassium and Related Disorders
- Lung Cancer Diagnosis and Treatment
- Healthcare Policy and Management
- Cardiac Structural Anomalies and Repair
The University of Texas Southwestern Medical Center
2013-2024
Southwestern Medical Center
2013-2023
Washington University in St. Louis
2016
University of Colorado Anschutz Medical Campus
2014
VA Eastern Colorado Health Care System
2014
Outcomes Research Consortium
2013-2014
University of Colorado Denver
2012-2013
Cooper Institute
2012
Kaiser Permanente
2012
Denver VA Medical Center
2012
Rates of testosterone therapy are increasing and the effects on cardiovascular outcomes mortality unknown. A recent randomized clinical trial in men with a high prevalence diseases was stopped prematurely due to adverse events raising concerns about safety.To assess association between all-cause mortality, myocardial infarction (MI), or stroke among male veterans determine whether this is modified by underlying coronary artery disease.A retrospective national cohort study low levels (<300...
Higher coronary artery calcium (CAC) identifies individuals at increased atherosclerotic cardiovascular disease (ASCVD) risk. Whether it can also identify likely to derive net benefit from aspirin therapy is unclear.To examine the association between CAC, bleeding, and ASCVD explore estimated effect of different CAC thresholds.Prospective population-based cohort study Dallas Heart Study participants, free not taking baseline. Data were analyzed February 1, 2020, July 15, 2020.Coronary score...
Background— The inverse, dose-dependent association between cardiorespiratory fitness and mortality is well-established; however, the pattern of low across short- (0 to 10 years), intermediate- (10 20 long-term (>20 years) follow-up has not been studied. Methods Results— We included 46 575 men 16 151 women (mean age 44 from Cooper Center Longitudinal Study. Participants were categorized as either “low fit” or “not fit,” based on age- sex- adjusted treadmill times, followed for mortality,...
<h3>Importance</h3> High-sensitivity cardiac troponin T (hs-cTnT) protocols for the evaluation of chest pain in emergency department (ED) may reduce unnecessary resource use and overcrowding. <h3>Objective</h3> To determine whether implementation a novel hs-cTnT protocol, which incorporated values drawn at 0, 1, 3 hours after ED presentation modified HEART score (history, electrocardiogram, age, risk factors), was associated with improvements while maintaining safety. <h3>Design, Setting,...
Background High‐sensitivity troponin I (hs‐cTnI) and T (hs‐cTnT) provide complementary information regarding cardiovascular disease risk. The explanation for their distinct risk profiles is incompletely understood. Methods Results hs‐cTnI hs‐cTnT were measured in Dallas Heart Study participants. Associations of with demographics phenotypes assessed using linear regression. incident heart failure, atherosclerotic disease, global all‐cause mortality Cox models. Among 3276 participants (56%...
Background— Medication adherence and treatment intensification have been advocated as performance measures to assess the quality of care provided. Whereas previous studies shown that (TI) antihypertensive medications is associated with blood pressure (BP) control at patient level, less known about whether TI BP clinic level. Methods Results— We included 162 879 patients among 89 clinics in Cardiovascular Research Network Hypertension Registry incident hypertension who were started on...
Background— Despite calls to expand measurement of acute myocardial infarction (AMI) outcomes include symptom burden, little has been done describe hospital-level variation in this patient-centered outcome, or its association with mortality. Understanding the relationship between symptoms and longer-term mortality could inform importance these for monitoring quality care. Methods Results— Among 4316 patients AMI treated at 24 hospitals participating Translational Research Investigating...
Acute coronary syndrome (ACS) is a common diagnosis in the emergency department (ED). Missing this may lead to increased morbidity or mortality. With improved cardiac biomarkers tests, it unknown if that has decreased prevalence of ACS diagnoses ED patients who were recently evaluated ED.This retrospective review diagnosed with and seen 7 30 days before visit North Texas between 2009 2015. The demographics temporal trends missed rates are described. Logistic regression was used evaluate any...
Although hospitalization for acute decompensated heart failure (HF) is common and associated with poor outcomes high costs, few evidence-based recommendations are available to guide patient management. Thus, management of inpatient HF remains heterogeneous. We evaluated if physician-specific self-reported practice patterns were 2 important contributors resource utilization: length stay (LOS) 30-day readmission.A 5-point Likert scale survey was created assess discharge strategies administered...
Background Premature clopidogrel discontinuation after drug‐eluting stent placement is associated with adverse outcomes. Little known about patient and hospital factors premature or whether less variation in exists integrated health care systems such as the Veterans Affairs (VA). Methods Results We evaluated frequency of discontinuation, defined a gap between refills ≥90 days during first 6 months treatment, among 12 707 patients who received stents VA hospitals 2008 2010. association...
Background: Focused cardiac ultrasound (FCU) has been used to answer clinical questions. Chemotherapy-related cardiotoxicity (CRR) is an entity that requires serial echocardiography. It unknown whether FCU can be screen for CRR using advanced practice providers (APPs). The goal of this study determine if reliably evaluate left ventricular ejection fraction (EF) by APP assess CRR. Methods: was conducted at the Echo lab and Oncology clinic. An trained on use EF analysis. obtained standard 2D...
Dual antiplatelet therapy (DAPT) is a class I guideline indication after percutaneous coronary intervention (PCI). Our population high-risk for low medication adherence. With multidisciplinary team we developed telephone-based to improve DAPT adherence post-PCI. Patients undergoing PCI at our center were contacted by nursing staff via telephone 1 week, 30 days, and 60 days post-procedure. Calls included reminder of the importance elicited any patient concerns. Concerns relayed who could take...
Vessel Plus is an open acccess journal, which publishes articles related to vascular diseases, including acute respiratory distress syndrome, aneurysm, atherosclerosis, hypertension, stroke, peripheral or pulmonary etc.
OBJECTIVES/GOALS: Tropsensor, a noninvasive portable device using infrared spectroscopy, delivers troponin res ult within five minutes, significantly quicker than standard of care (SOC) assays. This pilot study assesses the correlation Tropsensor and high sensitivity cardiac (hs-cTnI) assay results. METHODS/STUDY POPULATION: Patients undergoing cTnI testing with Abbott Architect STAT (Abbott Laboratories) hs-cTnI were recruited at quaternary-care emergency department (ED). The was applied to...