A5101851643- Gut microbiota and health
- Protein Structure and Dynamics
- Epigenetics and DNA Methylation
- RNA modifications and cancer
- Appendicitis Diagnosis and Management
- RNA and protein synthesis mechanisms
- Diverticular Disease and Complications
- Efficiency Analysis Using DEA
- Thyroid and Parathyroid Surgery
- Craniofacial Disorders and Treatments
- Healthcare cost, quality, practices
- Mass Spectrometry Techniques and Applications
- Transgenic Plants and Applications
- Connective tissue disorders research
- Metabolomics and Mass Spectrometry Studies
- Genomics and Phylogenetic Studies
- Mesenchymal stem cell research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Migration, Health and Trauma
- Cardiac, Anesthesia and Surgical Outcomes
- Machine Learning in Bioinformatics
- Cancer Research and Treatments
- Energy, Environment, Economic Growth
- Healthcare Policy and Management
- Plant Virus Research Studies
Indian Institute of Integrative Medicine
2024
The University of Texas Southwestern Medical Center
2019-2023
VA North Texas Health Care System
2022-2023
Training Programs in Epidemiology and Public Health Interventions Network
2022-2023
Cedars-Sinai Smidt Heart Institute
2023
Cedars-Sinai Medical Center
2023
Drexel University
2017-2020
Arni University
2019
University of Toledo
2013
Mallinckrodt (United States)
2011
Abstract Background Lung cancer is the leading diagnosis worldwide and number one cause of deaths. Exposure to cigarette smoke, primary risk factor in lung cancer, reduces epithelial barrier integrity increases susceptibility infections. Herein, we hypothesize that somatic mutations together with smoke generate a dysbiotic microbiota associated carcinogenesis. Using tissue from 33 controls 143 cases, conduct 16S ribosomal RNA (rRNA) bacterial gene sequencing, RNA-sequencing data cases The...
Importance Although the incidence of acute appendicitis among adults 65 years and older is high, these patients are underrepresented in randomized clinical trials comparing nonoperative vs operative management appendicitis; it unclear whether current trial data can be used to guide treatment adults. Objective To compare outcomes following assess they differ from results younger patients. Design, Setting, Participants This retrospective cohort study US hospital admissions Agency for...
Recent surges in large-scale mass spectrometry (MS)-based proteomics studies demand a concurrent rise methods to facilitate reliable and reproducible data analysis. Quantification of proteins MS analysis can be affected by variations technical factors such as sample preparation acquisition conditions leading batch effects, which adds noise the set. This may turn affect effectiveness any biological conclusions derived from data. Here we present Batch-effect Identification, Representation,...
Craniosynostosis (CS), the premature ossification of cranial sutures, is attributed to increased osteogenic potential resident osteoblasts, yet contribution surrounding extracellular matrix (ECM) on differentiation unclear. The osteoblast-secreted ECM provides binding sites for cellular adhesion and regulates transport signaling osteoinductive factors secreted by underlying dura mater. affinity each factor may amplify or mute its relative effect, thus contributing rate suture fusion. purpose...
The aim of this study is to investigate the influence macrophages on osteoblast (OB) performance and differentiation. In regard, we studied secretion growth factors including bone morphogenetic proteins (BMPs) from before after activation macrophages. We also evaluated osteogenic markers in co-culture OBs. were seeded microparticles (MPs) based chitosan (CS). Two types MPs fabricated CS 10% calcium phosphate (CaHPO4 )-incorporated MPs. Macrophage was activated using lipopolysaccharide (LPS)....
Following publication of the original paper [1], authors submitted a new Additional file 5 to replace one containing formatting issues. The updated is published in this correction.
Abstract Background Lung cancer is the leading diagnosis worldwide and number one cause of deaths. Exposure to cigarette smoke, primary risk factor in lung cancer, reduces epithelial barrier integrity increases susceptibility infections. Herein, we hypothesized that somatic mutations together with smoke generate a dysbiotic microbiota associated carcinogenesis. Using tissue from controls (n=33) cases (n=143), conducted 16S rRNA bacterial gene sequencing, RNA-seq data The Cancer Genome Atlas...
The present study estimates technical efficiency (TE) by developing Translog stochastic frontier approach. also verifies causal relationship between and advances using panel Granger causality test. experienced an increasing trend in terms of level efficiency. public sector banks emerged relatively more efficient than other ownership groups. found that priority to total advances, marker share non-performing assets are positively associated while loanable funds liabilities is negatively...
Protein domains exist by themselves or in combination with other to form complex multidomain proteins. Defining domain boundaries proteins is essential for understanding their evolution and function but not trivial. More specifically, partitioning that interact forming a single β-sheet known be particularly troublesome automatic structure-based decomposition pipelines. Here, we study edge-to-edge β-strand interactions between protein chain, help define the some more difficult cases where...
Abstract Lung cancer is the leading diagnosis worldwide and number one cause of deaths. Exposure to cigarette smoke, primary risk factor in lung cancer, reduces epithelial barrier function increases susceptibility infections. Herein, we hypothesized that somatic mutations together with smoke create a dysbiotic microbiota associated carcinogenesis. Using tissue from controls (n=33) or cases (n=143), conducted 16S rRNA gene sequencing (MiSeq), RNA-seq data The Cancer Genome Atlas (n=1112)...
MEta-Server for protein Sequence Analysis (MESSA) is a tool that facilitates widespread sequence analysis by gathering structural (local properties and three-dimensional structure) functional (annotations from SWISS-PROT, Gene Ontology terms, enzyme classification) predictions query of interest. MESSA uses multiple well-established tools to offer consensus-based on important aspects analysis. Being freely available noncommercial users with user-friendly interface, serves as an umbrella...