- Research in Cotton Cultivation
- Plant Molecular Biology Research
- Fungal Plant Pathogen Control
- Metabolism, Diabetes, and Cancer
- Plant Pathogens and Fungal Diseases
- Neurobiology and Insect Physiology Research
- Plant and Fungal Species Descriptions
- Pancreatitis Pathology and Treatment
- Seed Germination and Physiology
- Natural Compound Pharmacology Studies
- Plant Gene Expression Analysis
- Ecology and Conservation Studies
- Developmental Biology and Gene Regulation
- Plant-Microbe Interactions and Immunity
- Epigenetics and DNA Methylation
- Mycotoxins in Agriculture and Food
- Lipid metabolism and disorders
- Traditional Chinese Medicine Analysis
- Flavonoids in Medical Research
- Silk-based biomaterials and applications
- Cardiac and Coronary Surgery Techniques
- Autophagy in Disease and Therapy
- Lipid metabolism and biosynthesis
- Cancer, Lipids, and Metabolism
- Cardiac Fibrosis and Remodeling
Anhui Agricultural University
2024-2025
Nanjing Agricultural University
2022-2024
Naval Medical Center San Diego
2024
Shanghai Sixth People's Hospital
2021-2024
Shanghai Jiao Tong University
2021-2024
Jiyang College of Zhejiang A&F University
2023
West China Second University Hospital of Sichuan University
2022
Sichuan University
2022
Qinghai University
2021
Leiden University
2020
Stimulation of adipose tissue thermogenesis is regarded as a promising avenue in the treatment obesity. However, pharmacologic engagement this process has proven difficult. Using Connectivity Map (CMap) approach, we identified phytochemical hyperforin (HPF) an anti-obesity agent. We found that HPF efficiently promoted by stimulating AMPK and PGC-1α via Ucp1-dependent pathway. LiP-SMap (limited proteolysis-mass spectrometry) combined with microscale thermophoresis assay molecular docking...
Fusarium head blight (FHB), caused by the graminearum species complex, is a devastating disease of wheat and other cereal crops. This study investigates antifungal mechanism novel fungicide benziothiazolinone (BIT) against asiaticum (Fa) its synergistic effect with tebuconazole (TB). BIT could inhibit NADH ATP production lead to mitochondrial fragmentation, thereby inhibiting mycelial growth Fa. Besides, mixing TB at 1:1 showed an obvious Fa based on significantly reactive oxygen DON...
SUMMARY Drought has a severe impact on the quality and yield of cotton. Deciphering key genes related to drought tolerance is important for understanding regulation mechanism stress breeding drought‐tolerant cotton cultivars. Several studies have demonstrated that NAC transcription factors are crucial in stress, however, functional mechanisms still largely unexplored. Here, we identified factor GhNAC4 positively regulated The expression was significantly induced by abiotic plant hormones....
Abstract Objective Betaine–homocysteine methyltransferase (Bhmt) belongs to the family of methyltransferases and is involved in one‐carbon metabolic cycle, which associated with risk diabetes adiposity. This study aimed explore whether Bhmt participated development obesity or its diabetes, as well mechanism involved. Methods The expression levels were examined stromal vascular fraction cells mature adipocytes nonobesity. Knockdown overexpression C3H10T1/2 used investigate Bhmt's function...
Obstructive sleep apnea syndrome (OSAS), characterized by chronic intermittent hypoxia (CIH), is an independent risk factor for aggravating non-alcoholic steatohepatitis (NASH). The prevailing mouse model employed in CIH research inadequate the comprehensive exploration of impact on NASH development due to reduced food intake observed CIH-exposed mice, which deviates from human responses. To address this issue, a pair-feeding investigation with and normoxia-exposed mice conducted. It...
Many etiologies of acute liver injury (ALI) include drug-induced (DILI), viral illness, and autoimmune disease. Acute pancreatitis is an uncommon though significant etiology ALI caused by inflammation, fluid shifts, ischemia secondary to microthrombi formation that can progress failure if left untreated. We present a case hypertriglyceridemia-induced resulting in injury-associated (LIAAP) concurrent consumptive coagulopathy consistent with ischemic hepatopathy. Through treatment her...
In eudicots, germination begins with water uptake by the quiescent dry seed and is greatly related to permeability of micropyle enriched callose layers. Once imbibition starts, seeds undergo a cascade physiological, biochemical, molecular events initiate cellular activities. However, effects on following metabolic during are largely unknown. Cotton (Gossypium hirsutum) eudicot plant natural fiber edible oil production for humans. Here, we addressed this question examining role GhGLU19, gene...
Previous studies have shown that various preoperative inflammatory indicators can predict the prognosis of hepatocellular carcinoma (HCC), but role postoperative remains unclear. This study aimed to explore prognostic value and whether combining improve predictive performance model.Eighty-eight patients with primary HCC were included in this study. A model, combined model integrated established. The models was evaluated by area under curve time-dependent receiver operating characteristic...
The longstanding use of Drosophila as a model for cell and developmental biology has yielded an array tools. Together, these techniques have enabled analysis from variety methodological angles. Live imaging is emerging method observing dynamic processes, such division or motility. Having isolated mutations in uncharacterized putative cycle proteins it became essential to observe mitosis situ using live imaging. Most studies focused on the embryonic stages that are accessible manipulation...
This study explores the response and benefits of medicinal plant Scutellaria baicalensis to ecological environment under different planting modes, aiming gain a deeper understanding its characteristics impact modes.This analyzes baicalensis, with focus on growth requirements.Further investigation into modes environment, including traditional cultivation, organic farming, comparison between hydroponics soil is conducted.In arid regions, hydroponic cultivation demonstrates advantages, albeit...
SUMMARY Seeds are initiated from the carpel margin meristem (CMM) and high seed yield is top one of breeding objectives for many crops. β‐1,3‐glucanases play various roles in plant growth developmental processes; however, whether it participates CMM development formation remains largely unknown. Here, we identified a β‐1,3‐glucanase gene ( GLU19 ) as determinant callose deposition cotton. was differentially expressed tissues between Gossypium barbadense Gb hirsutum Gh ). Based on...
CRISPR/Cas9 technology, as a revolutionary gene editing tool, has garnered widespread attention in the field of plant biology.This review focuses on ginseng (Panax ginseng) and explores application technology targeted ginsenoside biosynthesis pathway, well its potential impact medicinal value.Panax ginseng, significant traditional herb, contains bioactive compounds known ginsenoside, which possess various properties such immunomodulation, anti-fatigue, anti-cancer effects.To enhance...
The longstanding use of Drosophila as a model for cell and developmental biology has yielded an array tools. Together, these techniques have enabled analysis from variety methodological angles. Live imaging is emerging method observing dynamic processes, such division or motility. Having isolated mutations in uncharacterized putative cycle proteins it became essential to observe mitosis situ using live imaging. Most studies focused on the embryonic stages that are accessible manipulation...
Leguminosae sp. is a family under the order of Rosales in class Dicotyledoneae, belonging to trees, shrubs, subshrubs or herbs, erect climbing, and often has nodules that can fix nitrogen. Discovered fossil evidence been found began diversify about 60 million years ago. Since its evolution, become third largest land plant terms number species, only next Orchidaceae Asteraceae family, economically, second Gramineae family. Research on legume classification system subject debate research by...
Objectives This study aimed at developing a dynamic prediction model for patients with Ewing sarcoma (ES) to provide predictions different follow-up times. During follow-up, disease-related information becomes available, which has an impact on patient’s prognosis. Many models include predictors available baseline and do not consider the evolution of disease over time. Setting In analysis, 979 ES from Gesellschaft für Pädiatrische Onkologie und Hämatologie registry, who underwent surgery...