A5038853266- Spine and Intervertebral Disc Pathology
- Nutrition and Health in Aging
- MicroRNA in disease regulation
- Gastric Cancer Management and Outcomes
- Orthopedic Infections and Treatments
- Pelvic and Acetabular Injuries
- Spinal Fractures and Fixation Techniques
- Bone Metabolism and Diseases
- Muscle Physiology and Disorders
- Bone Tissue Engineering Materials
- Colorectal Cancer Treatments and Studies
- Extracellular vesicles in disease
- Infectious Diseases and Tuberculosis
- Hemodynamic Monitoring and Therapy
- Frailty in Older Adults
- Pressure Ulcer Prevention and Management
- Blood Pressure and Hypertension Studies
- Diabetic Foot Ulcer Assessment and Management
- Reconstructive Surgery and Microvascular Techniques
- Orthopedic Surgery and Rehabilitation
- Antimicrobial Resistance in Staphylococcus
- Reconstructive Facial Surgery Techniques
- Liver physiology and pathology
- Kruppel-like factors research
- Embedded Systems and FPGA Design
Guangdong Medical College
2025
First People's Hospital of Yunnan Province
2022-2025
Kunming University of Science and Technology
2022-2025
Peking University
2015-2025
Peking University Cancer Hospital
2015-2025
Kunming Medical University
2020-2022
Peng Huanwu Center for Fundamental Theory
2022
Institute of Crop Sciences
2020
Chinese Academy of Agricultural Sciences
2020
Ningbo Medical Center Lihuili Hospital
2019
We have used an animal model to test the reliability of a new portable continuous-wave Doppler ultrasonic cardiac output monitor, USCOM. In six anesthetized dogs, was measured with high-precision transit time flowprobe placed on ascending aorta. The dogs' increased dopamine infusion (0-15 microg x kg(-1) min(-1)). Simultaneous and USCOM measurements were made. Up 64 pairs readings collected from each dog. Data compared by using Bland Altman plot method Lin's concordance correlation...
Muscle mass reduction (MMR) is one of the three etiologic criteria in Global Leadership Initiative on Malnutrition (GLIM) framework. This study aimed to evaluate value MMR GLIM among ambulatory cancer patients.A single-center prospective cross-sectional was conducted. All participants underwent calf circumference (CC) measurement and body composition by bioelectrical impedance analysis (BIA). identified CC, fat-free index (FFMI), appendicular skeletal muscle (ASMI), or combinations above...
335 Background: Blocking TGF-β signaling has the potential to facilitate recovery from chemo-induced myelosuppression. SHR-1701 is a bifunctional agent targeting PD-L1 and TGF-β. Methods: In multicenter, randomized, double-blind phase 3 study (NCT04950322), plus CAPOX demonstrated statistically significant clinically meaningful benefit in OS compared with placebo patients (pts) previously untreated, unresectable locally advanced or metastatic HER2-negative G/GEJA (ESMO 2024, LBA60). Here, we...
To explore the clinical characteristics of percutaneous vertebroplasty (PVP) via unilateral transverse process-pedicular (UTPP) approach in treatment osteoporotic vertebral compression fracture (OVCF) elderly. A total 120 elderly patients with lumbar OVCF who underwent PVP pedicular (UTP) and UTPP approaches our hospital from January 2022 to 2024 were retrospectively analyzed. The postoperative VAS score (visual analog scale), ODI (Oswestry disability index), surgical indicators, imaging...
A number of studies have examined human epidermal growth factor receptor 2 (HER2) status in primary gastric cancer (GC) and associated metastasis, some showed their great concordance HER2 expression, but others demonstrated notable discordance. There is still little consensus on discordance, therefore, a systematic review meta-analysis was conducted to assess the discordance between GC its paired metastasis.PubMed, EMBASE, ASCO The Cochrane Library were searched for that explored tumor...
Abstract Developing salt-tolerant crop varieties is one of the important approaches to cope with increasing soil salinization worldwide. In this study, a diversity panel 323 wheat accessions and 150 doubled haploid lines were phenotyped for salt-responsive morphological physiological traits across two growth stages. The comprehensive salt tolerance each accession was evaluated based on principal component analysis. A total 269 associated loci and/or indices identified by genome-wide...
Statement of RetractionWe, the Publisher journal Bioengineered, have retracted following article:Zhi Peng et al - Exosomes from bone marrow mesenchymal stem cells promoted osteogenic differentiation by delivering miR-196a that targeted Dickkopf-1 to activate Wnt/β-catenin pathway, Bioengineered (2021) (DOI: https://www.10.1080/21655979.2021.1996015)Since publication, significant concerns been raised about integrity data and reported results in article. When approached for an explanation,...
Sarcopenia is defined as an age-related progressive loss of muscle mass and/or strength. Although different factors can contribute to this disease, the underlying mechanisms remain unclear. We assessed transcriptional heterogeneity in skeletal muscles from sarcopenic and control mice at single-cell resolution.
Here, we present 3 different perspectives on how the microbiome has impacted cancer patients, treatment, and clinical studies. We hear about challenges of implementing analyses into clinics, impact these might have patients' care, treatment in future, specifically for gastric treatment. These are a few many voices that highlighting role development, outcomes.
Abstract Background Ambulatory cancer patients are at high risk of malnutrition. Multiple nutrition screening and assessment tools used in the outpatient setting. This study aimed to evaluate efficacy different as first step Global Leadership Initiative on Malnutrition (GLIM) framework Chinese ambulatory patients. Methods A cross‐sectional was conducted a tertiary hospital China. diagnoses made by GLIM using Screening Tool, Universal Nutritional Risk 2002, or short‐form Patient‐Gernerated...
In Brief the vasodilated and septic patient, impedance method of measuring cardiac output (CO) may underestimate true value. this study, we sought to determine whether CO (COIC) measurements are influenced by total peripheral resistance (TPR). eight anesthetized ventilated dogs, a high-precision flowprobe was placed on ascending aorta, direct measured (CO (COFP)). Mean arterial blood pressure from femoral artery. Simultaneous COIC were made. TPR (mean × 80/COFP) varied over 1–2 h using...
Abstract Infigratinib, an FGFR1‐3 selective oral tyrosine kinase inhibitor, has shown clinical activity in cancers with FGFR alterations. The pharmacokinetics (PK) of infigratinib and its major metabolites have been characterized global populations. This study examined the PK profile Chinese patients. In this phase II, open‐label, single‐arm China, patients advanced gastric cancer (GC) or gastroesophageal junction adenocarcinoma (GEJ) harboring FGFR2 gene amplification received 125 mg orally...
Sepsis-induced thrombotic microangiopathy is successfully treated by plasma exchange therapy. However, certain putative mediators of may not be removed filtration.We conducted an in vitro study to determine whether filtration can remove ultralarge von Willebrand factor (ULvWF) multimers and other mediators. In separate experiments, human umbilical venous endothelial cell (HUVEC) supernatant enriched with ULvWF or whole blood was passed through a therapeutic (TPE 2000, PRISMA) filter samples...
Study Design A single-institution retrospective study of a cohort patients who underwent internal fixation spine surgery for thoracolumbar burst fracture (TLBF). Objective To observe the imaging manifestations intervertebral disc changes in TLBF, to analyze relationship between degree injury and Cobb angle increase. Methods We retrospectively analyzed data short-segment pedicle screw instrumentation spinal department single hospital January 2014 December 2017 ( n = 90). According magnetic...
Background: Cellular metabolic dysfunction is associated with occurrence of multiple‐organ failure after critical illness. Glutamine (GLN) attenuates cellular in illness models. The mechanism this protection unclear. We previously demonstrated that GLN′s benefit might be due to enhanced heat shock protein (HSP) expression. hypothesize attenuation dependent on presence factor‐1 (HSF‐1). Methods: HSF‐1 wild‐type and knockout mouse embryonic fibroblasts (HSF‐1+/+ HSF‐1–/–) were used all...