Li Gui

ORCID: 0000-0002-6131-2134
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About
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Research Areas
  • Nanoplatforms for cancer theranostics
  • Photodynamic Therapy Research Studies
  • Porphyrin and Phthalocyanine Chemistry
  • Bone Tissue Engineering Materials
  • Mesenchymal stem cell research
  • Civil and Geotechnical Engineering Research
  • Traditional Chinese Medicine Analysis
  • Traditional Chinese Medicine Studies
  • Slime Mold and Myxomycetes Research
  • biodegradable polymer synthesis and properties
  • Diatoms and Algae Research
  • Graphene and Nanomaterials Applications
  • Healthcare and Venom Research
  • Plant tissue culture and regeneration
  • Biofuel production and bioconversion
  • Soil, Finite Element Methods
  • Allelopathy and phytotoxic interactions
  • Orthopaedic implants and arthroplasty
  • Seaweed-derived Bioactive Compounds
  • Drug Solubulity and Delivery Systems
  • Fungal Plant Pathogen Control
  • Evaluation and Optimization Models
  • Seed Germination and Physiology
  • Biological and pharmacological studies of plants
  • Conducting polymers and applications

Third People's Hospital of Yunnan Province
2013-2024

Nanjing Normal University
2015-2021

Nanjing Xiaozhuang University
2021

Analysis and Testing Centre
2016

South China Botanical Garden
2006

Chinese Academy of Sciences
2006

Daqing Oilfield General Hospital
2005

Yong In University
2003

Shaanxi Research Association for Women and Family
2002

Ling Tung University
2000

Wound healing is a highly orchestrated process involving variety of cells, including immune cells. Developing immunomodulatory biomaterials for regenerative engineering applications, such as bone regeneration, an appealing strategy. Herein, inspired by the effects gastrodin (a bioactive component in traditional Chinese herbal medicine), series new gastrodin-comprising biodegradable polyurethane (gastrodin-PU) and nano-hydroxyapatite (n-HA) (gastrodin-PU/n-HA) composites were developed. RAW...

10.1016/j.bioactmat.2022.03.037 article EN cc-by-nc-nd Bioactive Materials 2022-04-01

The development of functional materials for osteoporosis is ultimately required bone remodeling. However, grafts were accompanied by increasing pro-inflammatory cytokines that impaired formation. In this work, nano-hydroxyapatite (n-HA)/resveratrol (Res)/chitosan (CS) composite microspheres designed to create a beneficial microenvironment and help improve the osteogenesis local sustained release Res. Study in vitro confirmed feasibility n-HA/Res/CS controlled Res release. Notably, had...

10.1016/j.bioactmat.2020.10.018 article EN cc-by-nc-nd Bioactive Materials 2020-11-08

Hypoxic tumor treatment by synergistic of photodynamic therapy and ATP deprivation.

10.1039/c8tb00334c article EN Journal of Materials Chemistry B 2018-01-01

Abstract Increasing occurrences of degenerative diseases, defective tissues, and severe cancers heighten the importance advanced biomedical treatments, which in turn enhance need for improved biomaterials with versatile theranostic functionalities yet using minimal design complexity. Leveraging advantages citrate chemistry, a multifunctional citrate‐based biomaterial platform is developed both imaging therapeutic capabilities utilizing facile efficient one‐pot synthesis. The resulting...

10.1002/adfm.201801787 article EN Advanced Functional Materials 2018-06-26

Resveratrol (RSV) could promote osteogenic activity, but its clinical application has been hampered in view of poor bioavailability. Therefore, it is desirable to identify with certainty the molecular target bone mass boosting function, which crucial design an effective therapeutic strategy for optimal treatment osteoporosis. Emerging evidence indicated that GATA-1, important transcription factor megakaryocyte and erythrocyte differentiation, can directly activate autophagy erythrocytes,...

10.1093/abbs/gmab135 article EN Acta Biochimica et Biophysica Sinica 2021-09-15

The regeneration of osteoporotic bone defects remains challenging as the critical stem cell function is impaired by inflammatory microenvironment. Synthetic materials that intrinsically direct osteo-differentiation versus self-renewal recruited represent a promising alternative strategy for endogenous formation. Therefore, microenvironmentally optimized polyurethane (PU) /n-HA scaffold to enable sustained delivery gastrodin engineered study its effect on osteogenic fate cells. It exhibited...

10.1186/s12951-024-02886-7 article EN cc-by-nc-nd Journal of Nanobiotechnology 2024-11-20
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