A5101633057- Tuberculosis Research and Epidemiology
- Systemic Lupus Erythematosus Research
- Climate Change and Health Impacts
- Diagnosis and treatment of tuberculosis
- Psoriasis: Treatment and Pathogenesis
- Data-Driven Disease Surveillance
- Cardiac electrophysiology and arrhythmias
- Infectious Diseases and Tuberculosis
- Atherosclerosis and Cardiovascular Diseases
- Extracellular vesicles in disease
- Mycobacterium research and diagnosis
- Dermatology and Skin Diseases
- Acute Ischemic Stroke Management
- Neuroinflammation and Neurodegeneration Mechanisms
- Cancer-related molecular mechanisms research
- Circadian rhythm and melatonin
- Pneumocystis jirovecii pneumonia detection and treatment
- Air Quality and Health Impacts
- Inflammatory mediators and NSAID effects
- Pneumonia and Respiratory Infections
- Galectins and Cancer Biology
- Retinoids in leukemia and cellular processes
- Complement system in diseases
- Viral gastroenteritis research and epidemiology
- Asthma and respiratory diseases
Zhejiang Center for Disease Control and Prevention
2022-2025
Second Xiangya Hospital of Central South University
2025
Central South University
2025
Huashan Hospital
2025
Fudan University
2025
Chengdu Fifth People's Hospital
2024
Chengdu University of Traditional Chinese Medicine
2024
Zunyi Medical University
2024
Beijing Tongren Hospital
2014-2023
Shanghai University of Traditional Chinese Medicine
2021-2023
To investigate the temporal trends in mortality and disease burden of injuries Anhui province from 2008 to 2017, so as provide reference for injury control prevention.Data were collected 9 national surveillance points during 2008-2017 Information System Death Cause Register Management. The data analyzed by using crude mortality, standardized rate (SMR), potential year life lost (PYLL), PYLL (PYLLR), average (AYLL).There a total 44855 people died injury, accounted 9.44% all-cause ranked fifth...
Abstract Hypertrophy of the ligamentum flavum (LF) contributes to lumbar spinal stenosis (LSS), and results mainly from fibrosis. Connective tissue growth factor (CTGF) is a profibrotic involved in fibrotic process. This study aimed evaluate CTGF expression hypertrophied LF involvement hypertrophy. Ten patients with LSS were enrolled this study. The control group included 10 disc herniation. thickness was measured on preoperative axial T1‐weighted MRI. samples collected during surgery....
Abstract Objectives Several studies have reported increased serum/plasma adiponectin levels in SLE patients. This study was performed to estimate the causal effects of circulating on SLE. Methods We selected nine independent single-nucleotide polymorphisms that were associated with (P < 5 × 10−8) as instrumental variables from a published genome-wide association (GWAS) meta-analysis. The corresponding between and outcome (SLE) obtained an GWAS analysis, including 7219 cases 15 991...
Spinal cord injury (SCI) is a serious central nervous system disease, and secondary injury, including oxidative stress, the inflammatory response accompanying neuronal apoptosis, will aggravate condition. Due to existence of blood-spinal barrier (BSCB), existing drugs for SCI treatment are difficulty reach site thus their efficacy limited. In this study, we designed chitosan-modified hollow manganese dioxide nanoparticles (CM) delivery resveratrol help it pass through BSCB. Resveratrol...
Stroke is a central nervous system disease with high incidence at present. It can cause pathological changes such as oxidative stress, inflammation, neuronal apoptosis, and lead to disturbance of consciousness, disability, even death. Due the existence blood-brain barrier (BBB), most drugs cannot reach lesions exert their efficacy fully. Therefore, purpose this research was design lactoferrin functionalized hollow mesoporous manganese doped silica nanoparticles (LHMMSN) for delivery...
Tuberculosis remains a major public health challenge worldwide. This study aimed to determine the long-term trends in notification rate of tuberculosis Zhejiang Province, and assess potential independent risks associated with age, time period, birth cohort. Data on all pulmonary (PTB) cases Province from 2008 2022 were collected Information Management System. Long-term quantitatively decomposed variables determined using joinpoint regression model age-period-cohort model. Between 2022, total...
Many patients with coronavirus disease 2019 (COVID-19) may experience emotional issues and cognitive impairment. However, it remains unclear whether the brain mediates impact of COVID-19 on emergence psychopathological symptoms. It anxiety depression are caused by stressors or viral infection. To use functional near-infrared spectroscopy (fNIRS) to detect cortical hemodynamic changes in their relationship mental symptoms (mainly anxiety), investigate causes these affecting function. A total...
ABSTRACT Tuberculosis is a global public health threat as an infectious disease, and effective blocking of transmission relies on timely diagnosis. Although number laboratory tests are available in diagnosing Mycobacterium tuberculosis (MTB) nontuberculous mycobacteria (NTM), it still great need to evaluate their diagnostic value clinical samples. In this study, we evaluated five MTB methods (including conventional sputum smear microscopy, sandwich cup culture, Xpert‐MTB/RIF, CapitalBio...
Abstract Objective Although patients with psoriasis frequently report seasonal changes in their symptoms, the seasonality of has rarely been explored. This study aims to investigate pattern and global public interest using Google search data. Methods Internet data were collected from Trends. Data on relative volume (RSV) January 2004 December 2018 retrieved term psoriasis. Cosinor analyses conducted examine two southern hemisphere countries (Australia New Zealand) four northern (USA, Canada,...
Psoriasis is a common chronic immune-inflammatory disease. Challenges exist in the present treatment of psoriasis, such as difficulties transdermal drug administration and severe side effects. We hope to achieve better therapeutic outcome for psoriasis treatment. By using modified soluble microneedles (MNs) loaded with daphnetin, symptoms mice, abnormal proliferation keratinocytes, secretion inflammatory factors were significantly reduced. In vitro, daphnetin proven inhibit NF-κB signaling...
Recently, exposure to air pollutants has been associated with the development and progression of systemic lupus erythematosus (SLE). The current study aims evaluate effects on SLE hospital admissions in Bengbu, China. We performed distributed lag non-linear model combined quasi-Poisson generalized linear regression assess impacts from 2015 2017. Subgroup analyses by admission status (first or readmission) were also evaluated. A total 546 during 2015–2017 included. For single-day structures,...