- Bone Metabolism and Diseases
- GDF15 and Related Biomarkers
- Pelvic floor disorders treatments
- Nutrition and Health in Aging
- Urinary Bladder and Prostate Research
- Folate and B Vitamins Research
- Urinary Tract Infections Management
- Bone and Dental Protein Studies
- Osteoarthritis Treatment and Mechanisms
- Pancreatitis Pathology and Treatment
- Wnt/β-catenin signaling in development and cancer
- Infectious Diseases and Tuberculosis
- Nuclear Receptors and Signaling
- Electrospun Nanofibers in Biomedical Applications
- Mycobacterium research and diagnosis
- Neuroendocrine Tumor Research Advances
- Proteoglycans and glycosaminoglycans research
- Hernia repair and management
- Anorectal Disease Treatments and Outcomes
- Vitamin D Research Studies
- Free Radicals and Antioxidants
- Veterinary Equine Medical Research
- Oral and Maxillofacial Pathology
- Essential Oils and Antimicrobial Activity
- Mesenchymal stem cell research
Xiangya Hospital Central South University
2023
Central South University
2023
Shanghai Xuhui Central Hospital
2023
Xi'an Honghui Hospital
2022
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
2022
Children's Hospital of Chongqing Medical University
2021
Molecular Oncology (United States)
2021
Chongqing Medical University
2021
University of Chicago Medical Center
2021
University College Dublin
2021
Cartilage tissue has a relatively low regenerative capacity which leads to need for disease‐modifying active pharmaceutical ingredients (APIs) can stimulate its regeneration and more urgently, effective ways of introducing APIs into the cartilage defects. Herein, an integrated system is proposed in hyaluronic acid (HA)‐based injectable hydrogel scaffold embedded with API‐loaded poly( d , l ‐lactide‐co‐glycolide) microspheres (PLGA MPs). This new drug delivery successfully deliver locally,...
Abstract Background: Homocysteine (Hcy) is one of the main factors leading to arteriosclerosis, which closely related cardiovascular disease. Recent studies have found that serum Hcy levels are increased in patients with chronic heart failure (CHF), and it speculated may be a risk factor for CHF, but evidence-based medicine evidence lacking. The aim this study was investigate correlation between CHF by means systematic review. Methods: databases PubMed, Embase, Cochrance Library, Web...
Osteoarthritis (OA) is one of the most popular degenerative joint diseases. The nucleolar GTP binding protein 3 (GNL3) gene encodes guanine nucleotide protein-like 3, which related in cell proliferation, differentiation, and cycle regulation. Our study aimed to examine contribution GNL3 polymorphisms risk hand OA its clinical features. A total 3387 participants including 1160 patients with 2227 controls were recruited this study. Eleven SNPs selected for genotyping. Genetic association...
Background: Stress urinary incontinence (SUI) is defined as involuntary leakage of urine from the external urethra due to increased abdominal pressure, for example, upon sneezing, coughing, or exercise. Acupuncture an effective therapy patients with SUI, although objective evidence its benefits mechanism action limited. Patients SUI often harbor structural changes pelvic floor, parameters which are measurable various perspectives and in multiple dimensions, dynamically comprehensively,...
XXX.This study aimed to determine the impact of a rural vs urban hospital location on risk undergoing second surgery for stress urinary incontinence.Using Cerner Health Facts nationwide electronic medical record database, we identified patients who underwent surgeries incontinence between January 1, 2010 and November 30, 2018. Stress included synthetic midurethral slings, fascial retropubic urethral suspension, other incontinence, such as laparoscopic sling or Pereyra procedure. Patients...
Abstract Background : Stress urinary incontinence (SUI) is defined as involuntary leakage of urine due to increased abdominal pressure. Previous studies have confirmed that electroacupuncture an effective alternative approach for treating SUI; yet, objective evidence its mechanism action still lacking. Patients with SUI often harbor structural changes in the pelvic floor, which can be easily detected on transperineal ultrasound (TPUS). The aim this study was assess effect involving lower...
Folate is important for purine synthesis and DNA methylation. deficiency associated with uracil misincorporation, abnormal methylation in DNA, p53 gene mutation the loss of estrogen receptor (ER) expression, chromosome aberration micronuclei formation. alcohol act opposite directions breast carcinogenesis. may provide a new way cancer protection. Key words: Folic acid deficiency; Breast neoplasms; Genes; Alcohol drinking
Objective To observe the effect of individualized exercise programs on activity tolerance and life quality heart failure patients with a preserved ejection fraction. Methods Heart left ventricular fraction (LVEF) were randomized to an training group (n=55) or control (n=53). Both groups given optimized drug therapy, while was additionally provided training. The LVEFs, 6-minute walking distances (6MWDs), Minnesota living questionnaire (MLHFQ) scores adverse events noted before...
Abstract Background: Bone destruction is the key and difficult point in treatment of RA. Studies have found that use traditional Chinese medicine Qingre Huoxue Decoction (QRHXD) can effectively reduce disease activity delay bone destruction. Magnetic resonance imaging (MRI) one effective ways to evaluate RA real time, which helpful early evaluation discovery synovitis Therefore, we designed a multicenter, randomized, double-blinded, controlled clinical trial assess improvement QRHXD treating...